5-Amino-1-methylquinolinium chloride CAS No.:42464-96-0 98.0% chiyero cha mphindi | wopanga zowonjezera zowonjezera
Magawo a Zamalonda
| Dzina la chinthu | 5-Amino-1-methylquinolinium chloride (5-amino-1MQ) |
| Dzina lina | 5-amino-1MQ5-Amino-1-mq chloride 5-Amino-1-methylquinolinium chloride 5-Amino-1-methylquinolin-1-ium chloride 5-AMINO-1-METHYLQUINOLIN-1-IUM CHLOEIDE 5-Amino-1-methyl-1-quinolinium chloride |
| Nambala ya CAS | 42464-96-0 |
| Fomula ya maselo | C₁₀H₁₁ClN₂ |
| Kulemera kwa maselo | 194.6 |
| Chiyero | 98% |
| Maonekedwe | Cholimba cha bulauni mpaka chofiira |
| Kulongedza | 1kg/thumba, 25kg/mbiya |
| Kugwiritsa ntchito | Zakudya Zowonjezera Zakudya |
Chiyambi cha malonda
5-Amino-1-methylquinolinium chloride ndi enzyme yomwe imapangidwa mopitirira muyeso panthawi ya ukalamba wa minofu ya mafupa ndipo imagwirizanitsidwa ndi kukonzanso kuwonongeka kwa njira ya NAD+, ntchito ya sirtuin1 yosakhazikika bwino, komanso kuchuluka kwa ukalamba wa maselo a minofu. 5-Amino-1-methylquinolinium chloride imalimbikitsa kusiyana kwa myoblast mu vitro ndikuwonjezera kusakanikirana ndi kubwezeretsedwa kwa maselo a minofu m'makoswe okalamba. 5-Amino-1-methylquinolinium chloride ndi choletsa champhamvu cha nicotinamide N-methyltransferase (NNMT), chomwe chimamangirira mosankha ku zotsalira za malo omangira a NNMT. 5-Amino-1-methylquinolinium chloride imalimbikitsa kusiyana kwa myoblast mu vitro ndikuwonjezera kusakanikirana ndi kubwezeretsedwa kwa maselo a minofu m'makoswe okalamba. Pakati pawo, cytosolic enzyme nicotinamide N-methyltransferase (NNMT) yapezeka posachedwapa kuti ilamulire kuchuluka kwa nicotinamide precursors ofunikira pakupanga kwa NAD+, motero imagwira ntchito yofunika kwambiri pakulamulira njira yopulumutsira ya NAD+ ndi kagayidwe ka maselo.
5-Amino-1-Methylquinolinium Chloride imagwira ntchito mkati mwa microbiome yanu kuti ichepetse mafuta (mafuta) ndikukuthandizani kuchepetsa thupi. Pamene maselo owonjezera amafuta akusonkhana, thupi lanu limapanga enzyme yodziwika kuti NNMT (nicotinamide N-methyltransferase). NNMT ikachuluka, thupi lanu limawonjezera kutupa ndikusunga mafuta. 5-Amino-1-Methylquinolinium Chloride imaletsa NNMT, zomwe zimathandiza thupi lanu kuchepetsa kulemera kwambiri.
Mbali
(1) Kuyera kwambiri: 5-Amino-1-methylquinolinium chloride imatha kupeza zinthu zoyera kwambiri kudzera mu njira zopangira zoyengedwa bwino. Kuyera kwambiri kumatanthauza kupezeka bwino kwa bioavailability.
(2) Kuyang'anira: 5-Amino-1-methylquinolinium chloride imayang'ana makamaka enzyme ya NNMT ndipo imatha kuletsa bwino ntchito yake, motero imakhudza njira ya kagayidwe ka nicotinamide.
(3) Kukhazikika: 5-Amino-1-methylquinolinium chloride ili ndi kukhazikika kwabwino ndipo imatha kusunga ntchito ndi mphamvu zake pansi pa malo osiyanasiyana komanso malo osungiramo zinthu zosiyanasiyana.
(4) Ziyembekezo za chitukuko: Chifukwa cha makhalidwe osiyanasiyana a 5-Amino-1-methylquinolinium chloride, chitukuko chake chalandiridwa kwambiri ndipo chili ndi kafukufuku wochuluka komanso mwayi wogwiritsidwa ntchito.
Mapulogalamu
5-Amino-1-methylquinolinium chloride ndi mankhwala oletsa nicotinamide N-methyltransferase (NNMT) omwe amalimbikitsa kusiyana kwa myoblast. 5-Amino-1-methylquinolinium chloride ingagwiritsidwenso ntchito ngati chowonjezera chothandizira kuchepetsa kulemera ndi mafuta ndikuwonjezera mafuta m'chiwindi.
