Wopanga ufa wa Palmitoylethanolamide (PEA Granule) Nambala ya CAS: 544-31-0 97% kuyera kwa mphindi zochepa kwa zowonjezera zowonjezera

Palmitoylethanolamide ndi molekyulu ya lipid messenger yomwe idapezeka koyamba kumapeto kwa zaka za m'ma 1950. Ili m'gulu la mankhwala otchedwa endocannabinoids, omwe ndi zinthu zachilengedwe zomwe zimagwirizana ndi dongosolo la endocannabinoid la thupi. Mosiyana ndi ma cannabinoids ena monga THC omwe amapezeka mu chomera cha chamba, PEA siimayambitsa psychoactive ndipo siimabweretsa zotsatira zilizonse zosintha maganizo. Dongosolo la endocannabinoid (ECS) ndi netiweki yovuta ya ma receptor ndi ma endocannabinoids omwe amapezeka m'thupi lonse. Imagwira ntchito yofunika kwambiri pakulamulira njira zosiyanasiyana za thupi, kuphatikizapo kumva ululu, kutupa, ndi malingaliro. PEA imagwira ntchito ngati ligand ya endogenous ya receptor inayake mkati mwa ECS yotchedwa peroxisome proliferator-activated receptor-α (PPAR-α). Mwa kuyambitsa receptor iyi, PEA imagwiritsa ntchito mphamvu zake zotsutsana ndi kutupa komanso zopweteka. Kafukufuku akuwonetsa kuti Palmitoylethanolamide ingathandize kuthana ndi ululu wosatha, kuphatikizapo ululu wa neuropathic ndi kutupa. Imagwira ntchito pochepetsa kutulutsidwa kwa zinthu zoyambitsa kutupa ndikuwongolera kuyambika kwa maselo a chitetezo chamthupi omwe amakhudzidwa ndi kuyankhidwa kwa kutupa. Mayesero ambiri azachipatala awonetsa kuti PEA imagwira ntchito bwino pochepetsa ululu komanso kukonza moyo wa odwala omwe ali ndi matenda osiyanasiyana opweteka nthawi yayitali.