Wopanga ufa wa Nefiracetam Nambala ya CAS: 77191-36-7 99% kuyera pang'ono kwa zosakaniza zowonjezera

Kufotokozera Kwachidule:

Nefiracetam ndi m'gulu la mankhwala owonjezera nzeru omwe si a malire, omwe ali ndi kapangidwe ka mankhwala osiyanasiyana ndipo amawonjezera luso la kuzindikira komanso amaletsa kuwonongeka kwa kuphunzira ndi kukumbukira kudzera mu zotsatira zake pa ubongo.

Tumizani imelo kwa ife

Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Kanema wa Zamalonda

Magawo a Zamalonda

Dzina la chinthu	Nefiracetam
Dzina lina	n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMPA
Nambala ya CAS	77191-36-7
Fomula ya maselo	C14H18N2O2
Kulemera kwa maselo	246.3
Chiyero	99.0%
Maonekedwe	Ufa woyera
Kulongedza	25 kg/mgolo
Kugwiritsa ntchito	mankhwala a nootropic

Chiyambi cha malonda

Nefiracetam ndi ya m'banja la piracetam, gulu la mankhwala odziwika chifukwa cha mphamvu zawo zokulitsa chidziwitso. Nefiracetam idapangidwa koyamba kumayambiriro kwa zaka za m'ma 1980 ndipo idakopa chidwi mwachangu chifukwa cha njira yake yapadera yogwirira ntchito komanso njira zomwe zingagwiritsidwe ntchito pochiza. Chomera ichi cha racemic chimaganiziridwa kuti chimakhudza ma neurotransmitters ndi ma receptors muubongo, zomwe pamapeto pake zimathandizira luso lowongolera chidziwitso. Nefiracetam imakhudza kwambiri kuchuluka kwa acetylcholine muubongo, neurotransmitter yofunika kwambiri yomwe imayang'anira kukumbukira, kuphunzira, ndi ntchito ya chidziwitso. Mwa kusintha ma acetylcholine receptors, nefiracetam imalimbikitsa kulumikizana kwakukulu pakati pa ma neuron, motero kumawonjezera pulasitiki ya synaptic ndikuwonjezera kusunga kukumbukira. Kuphatikiza apo, nefiracetam imagwirizana ndi ma receptors a gamma-aminobutyric acid (GABA) kuti athandize kulinganiza malo a neurotransmitter. Mwa kukhudza bwino ma neurotransmitters olimbikitsa komanso oletsa, nefiracetam imathandiza kusunga ntchito yabwino ya ubongo, motero kumawongolera kuyang'ana, chidwi, komanso magwiridwe antchito onse a chidziwitso.

Mbali

(1) Kuyera kwambiri: Nefiracetam imatha kupeza zinthu zoyera kwambiri kudzera mu njira zopangira zinthu zoyeretsera. Kuyera kwambiri kumatanthauza kupezeka bwino kwa bioavailability komanso kuchepetsa zotsatirapo zoyipa.

(2) Chitetezo: Chitetezo chachikulu, zotsatirapo zochepa zoyipa.

(3) Kukhazikika: Nefiracetam ili ndi kukhazikika kwabwino ndipo imatha kusunga ntchito yake ndi mphamvu zake m'malo osiyanasiyana komanso m'malo osiyanasiyana osungira.

Mapulogalamu

Nefiracetam ndi chinthu chochokera ku piracetam chomwe chimachokera ku hydrophobic, chomwe nthawi zambiri chimaonedwa kuti ndi chinthu chomwe chimayambitsa kupezeka kwa njira za calcium m'thupi komanso kusamutsa mwachindunji zinthu zoyambitsa zizindikiro monga gawo la agonist ya njira za calcium ion. Malo omangira Glycine a NDMA receptor. Kudzera mu zotsatira zake pa cerebral cortex, nefiracetam imatha kukulitsa luso la kuzindikira ndikuletsa kulephera kuphunzira ndi kukumbukira. Sili ndi muscarinic receptor agonist kapena antagonist, komanso sililetsa ntchito ya acetylcholinease. Chifukwa chake, zotsatira zake zotsutsana ndi amnestic komanso zokulitsa kukumbukira zimapezeka powonjezera kutulutsidwa kwa acetylcholine mu cerebral cortex.