Sunifiram ufa wopanga CAS No.: 314728-85-3 99% chiyero min.kwa zowonjezera zowonjezera

Sunifiram ndi AMPA receptor agonist yomwe imathandizira ma signature kuchokera ku AMPA receptors muubongo, omwe nthawi zambiri amaganiziridwa kuti ndi osewera ofunikira okhudzana ndi kuphunzira ndi kukumbukira.Mwa kupititsa patsogolo ntchito ya AMPA zolandilira, Sunifiram imaganiziridwa kuti imakulitsa luso la ubongo kuti liphunzire ndi kukumbukira, komanso kukulitsa chidwi ndi mphamvu zamaganizidwe.Kuphatikiza apo, imagwira ntchito polimbikitsa ntchito ya ma glutamate receptors ndikuwonjezera kupanga ndi kutulutsidwa kwa "learning neurotransmitter" acetylcholine.Sunifiram imagwira ntchito makamaka ngati ampa factor, zomwe zikutanthauza kuti zimamangiriza ku AMPA-mtundu wa glutamate receptors mu ubongo pambuyo podutsa chotchinga cha magazi-ubongo.Izi zimathandizira kupanga glutamate, neurotransmitter yofunika kwambiri ku synaptic plasticity, kapena kuthekera kwa ma synapses a mitsempha kuyankha pakuwonjezeka kapena kuchepa kwa ntchito.Miyezo ya glutamate ndi yofunika kwambiri mu hippocampus, gawo la ubongo lomwe limagwira ntchito yaikulu pakuyenda kwa malo ndi kupanga kukumbukira ndi kusungirako, ndipo milingo yokwanira ya glutamate ndiyofunikira kuti pakhale kutha kwa nthawi yayitali, kapena kusintha kosatha, kwa mphamvu yazizindikiro pakati pa ma neuron. zofunika kwambiri.Maluso ambiri opititsa patsogolo chidziwitso a sunifiram pamapeto pake amakwaniritsidwa powonjezera mphamvu zama siginecha a neural mu gawo ili la ubongo.