J-147 wopanga ufa Nambala ya CAS: 1146963-51-0 99.0% kuyera pang'ono kwa zosakaniza zowonjezera
Magawo a Zamalonda
| Dzina la chinthu | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Dzina lina | J-147, J147 |
| Nambala ya CAS | 1146963-51-0 |
| Fomula ya maselo | C18H17F3N2O2 |
| Kulemera kwa maselo | 350.33 |
| Chiyero | 99% |
| Maonekedwe | Ufa woyera |
| Kulongedza | 1kg pa thumba lililonse |
| Kugwiritsa ntchito | mankhwala a nootropic |
Chiyambi cha Zamalonda
J-147 ndi mankhwala amphamvu kwambiri oteteza mitsempha m'kamwa omwe amachokera makamaka ku curcumin, chinthu chogwira ntchito mu turmeric. Mosiyana ndi curcumin, imadutsa bwino kwambiri chotchinga magazi ndi ubongo. Pakati pawo, J-147 imagwira ntchito polumikizana ndi ATP synthase. Kupanga kwambiri kwa ATP kumalumikizidwa ndi ukalamba. Kuphatikiza pa kuchulukitsa kuchuluka kwa ma neurotransmitters NGF ndi BDNF, J-147 imatha kuwongolera izi. Kuphatikiza apo, J-147 imaletsa monoamine oxidase B ndi dopamine transporter. Imathandizira kukula kwa ubongo mwa kuwonjezera kuchuluka kwa nerve growth factor (NGF) ndi brain-derived neurotrophic factor (BDNF). Chofunika kwambiri, J-147 imatha kulimbikitsa kukula kwa maselo atsopano a mitsempha, kukulitsa luso la ubongo lophunzira komanso kukumbukira, komanso kukonza magwiridwe antchito azidziwitso.
Mbali
(1) Kuyera kwambiri: J-147 imatha kupeza zinthu zoyera kwambiri kudzera mu njira zopangira zinthu zoyeretsera. Kuyera kwambiri kumatanthauza kupezeka bwino kwa bioavailability komanso kuchepetsa zotsatirapo zoyipa.
(2) Chitetezo: J-147 yatsimikiziridwa kuti ndi yotetezeka ku thupi la munthu.
(3) Kukhazikika: J-147 ili ndi kukhazikika kwabwino ndipo imatha kusunga ntchito yake ndi mphamvu zake pansi pa malo osiyanasiyana komanso malo osungiramo zinthu zosiyanasiyana.
(4) Yosavuta kuyamwa: J-147 imatha kuyamwa mwachangu ndi thupi la munthu, kulowa m'magazi kudzera m'matumbo, ndipo imafalikira ku minofu ndi ziwalo zosiyanasiyana.
Mapulogalamu
J-147 ndi mankhwala opangidwa omwe njira yake yaikulu yogwirira ntchito imaphatikizapo kuwonjezera mphamvu ya mitochondrial, motero kukulitsa kupanga mphamvu pamlingo wa maselo. J-147 idapangidwa kuti iwonjezere mphamvu ya ubongo yodzikonza ndikudziteteza ku kuwonongeka kokhudzana ndi ukalamba mwa kukonza ntchito ya mitochondrial. Kuphatikiza apo, J-147 ili ndi mphamvu zotsutsana ndi kutupa komanso antioxidant, zomwe zimawonjezera mphamvu zake zoteteza mitsempha. J-147 imatha kulimbikitsa kukula kwa maselo atsopano amitsempha, kukulitsa luso la ubongo lophunzira komanso kukumbukira, komanso kukonza magwiridwe antchito a ubongo.
