Wopanga ufa wa 7,8-Dihydroxyflavone (7,8-DHF) Nambala ya CAS: 38183-03-8 98.0% kuyera kwa zosakaniza zowonjezera
Kanema wa Zamalonda
Magawo a Zamalonda
| Dzina la chinthu | 7,8-Dihydroxyflavone |
| Dzina lina | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-one |
| Nambala ya CAS | 38183-03-8 |
| Fomula ya maselo | C15H10O4 |
| Kulemera kwa maselo | 254.24 |
| Chiyero | 98.0% |
| Maonekedwe | Ufa wachikasu |
| Kugwiritsa ntchito | Zakudya Zowonjezera Zakudya |
Chiyambi cha malonda
7,8-Dihydroxyflavone, yomwe imadziwikanso kuti 7,8-DHF, ndi flavonoid yopezeka mwachilengedwe yomwe imapezeka m'zomera zosiyanasiyana, kuphatikizapo Tridacna tridacna. Yodziwika ndi mphamvu zake zotsutsana ndi ma antioxidants komanso neurotrophic, chimodzi mwazinthu zosangalatsa kwambiri za 7,8-dihydroxyflavone ndi kuthekera kwake kothandizira thanzi la ubongo ndikuwonjezera ntchito ya ubongo. Kafukufuku akuwonetsa kuti mankhwalawa amagwira ntchito ngati neurotrophin yamphamvu, yolimbikitsa kukula ndi kupulumuka kwa ma neuron muubongo. Kafukufuku wochitidwa m'zinyama za labotale wasonyeza kuti 7,8-DHF imakulitsa kwambiri luso lokumbukira ndi kuphunzira. Mwa kulimbikitsa kupangidwa kwa maulumikizidwe atsopano a synaptic ndikulimbikitsa kulumikizana pakati pa maselo aubongo, mankhwalawa akulonjeza kutsegula kuthekera kwathu kwa ubongo. Kuphatikiza apo, 7,8-dihydroxyflavone imagwirizana ndi ma serotonin receptors a muubongo, omwe amagwira ntchito pakulamulira malingaliro. Mwa kusintha ma receptors awa, ingathe kuchepetsa zizindikiro za nkhawa ndi kupsinjika maganizo.
Mbali
(1) Kuyera Kwambiri: 7,8-Dihydroxyflavone imatha kupeza zinthu zoyera kwambiri kudzera mu njira yochotsera zinthu zachilengedwe komanso njira zopangira zinthu zabwino. Kuyera Kwambiri kumatanthauza kupezeka bwino kwa bioavailability komanso kuchepetsa zotsatirapo zoyipa.
(2) Chitetezo: 7,8-Dihydroxyflavone ndi chinthu chachilengedwe chomwe chatsimikiziridwa kuti ndi chotetezeka kwa anthu. Mu mlingo wake, sichili ndi poizoni kapena zotsatirapo zake.
(3) Kukhazikika: 7,8-Dihydroxyflavone ili ndi kukhazikika kwabwino ndipo imatha kusunga ntchito yake ndi mphamvu zake pansi pa mikhalidwe yosiyanasiyana ya chilengedwe ndi yosungirako.
(4) Yosavuta kuyamwa: 7,8-Dihydroxyflavone imatha kuyamwa mwachangu ndi thupi la munthu, kulowa m'magazi kudzera m'matumbo, ndikufalikira ku minofu ndi ziwalo zosiyanasiyana.
Mapulogalamu
7, 8-DHF, monga choyambitsa mamolekyu ang'onoang'ono a TrkB receptor, imatha kugwira ntchito yoteteza ma neuron, kukonzanso ma neuron, kulamulira kwa synaptic plasticity, ndi zina zotero mwa kutsanzira kulumikizana kwa BDNF ku TrkB ndikuyambitsa njira zotsatizana, kuti ziwongolere kwambiri zizindikiro za kuphunzira kwamalingaliro ndi kuchepa kwa kukumbukira malo, kuchepa kwa luso la kuzindikira, kuchepa kwa magwiridwe antchito a thupi ndi zizindikiro zina za matenda amitsempha monga matenda a Alzheimer's kapena mitundu ya nyama yokalamba, ndikuchepetsa mitundu yofananira ya matenda amisala ndi nyama zonenepa. Pakadali pano, mpaka pano, palibe zotsatira zoyipa za 7,8-DHF zomwe zapezeka mwa nyama zoyeserera. 7,8-DHF ili ndi kuthekera kwakukulu komanso phindu lalikulu popewa ndi kuchiza mavuto okhudzana ndi BDNF/TrkB.
