Oleoylethanolamide (OEA) wopanga ufa CAS No.: 111-58-0 98%,85% chiyero min. kwa zowonjezera zowonjezera
Product Parameters
| Dzina la malonda | Oleoyl ethanolamide |
| Dzina lina | N-oleoyl ethanolamine; N-(2-hydroxyethyl)-,(Z)-9-Octadecenamide |
| CAS No. | 111-58-0 |
| Molecular formula | C20H39NO2 |
| Kulemera kwa maselo | 325.53 |
| Chiyero | 98.0%, 85.0% |
| Maonekedwe | ufa wabwino wa kristalo woyera |
| Kulongedza | 1kg / thumba, 25kg / ng'oma |
| Kugwiritsa ntchito | Kuchepetsa ululu, anti-yotupa |
Chiyambi cha malonda
Oleoylethanolamide ndi gulu lachiwiri la amide lopangidwa ndi lipophilic oleic acid ndi hydrophilic ethanolamine. Oleoylethanolamide ndinso mamolekyu a lipid omwe amapezeka mwachilengedwe muzinthu zina zanyama ndi zomera. Zimapezeka kwambiri mu nyama ndi zomera monga ufa wa cocoa, soya, ndi mtedza, koma zomwe zilimo ndizochepa kwambiri. Pokhapokha pamene chilengedwe chakunja chikusintha kapena chakudya chikakondoweza, minyewa ya maselo a thupi Pokhapokha pamene zambiri za mankhwalawa zidzapangidwa.
Kutentha kwachipinda, Oleoylethanolamide ndi yoyera yolimba ndipo imasungunuka pafupifupi 50 ° C. Ndiwosavuta kusungunuka mu zosungunulira mowa monga methanol ndi Mowa, mosavuta sungunuka mu zosungunulira sanali polar monga n-hexane ndi efa, ndi insoluble m'madzi. OEA ndi molekyulu ya amphiphilic yomwe nthawi zambiri imagwiritsidwa ntchito ngati surfactant ndi detergent mumakampani opanga mankhwala. Komabe, kafukufuku wowonjezera adapeza kuti OEA imatha kukhala ngati molekyu yowonetsa lipid mum'matumbo-muubongo ndikuwonetsa zinthu zingapo zamoyo m'thupi, kuphatikiza: kuwongolera chilakolako, kukonza kagayidwe ka lipid, kukulitsa kukumbukira ndi kuzindikira ndi ntchito zina. Pakati pawo, ntchito za Oleoylethanolamide zowongolera kulakalaka komanso kukonza kagayidwe ka lipid zalandira chidwi kwambiri.
Oleoylethanolamide imatha kuwongolera kudya komanso mphamvu ya homeostasis poyambitsa peroxisome proliferator-activated receptor-α. Kuonjezera apo, Oleoylethanolamide imasonyeza ntchito zina zokhudzana ndi thanzi, kuphatikizapo kusintha ntchito yosinthira mu njira yowonetsera lysosomal-to-nyukiliya yokhudzana ndi malamulo a moyo wautali komanso kuteteza mitsempha yomwe imayendetsa makhalidwe okhumudwitsa. Kafukufuku akuwonetsanso kuti Oleoylethanolamide ikhoza kukhala ndi zotsatira za neuroprotective. M'zitsanzo za nyama, zapezeka kuti zimachepetsa kuwonongeka kwa sitiroko ndi kuvulala koopsa kwa ubongo. Kuwongolera kwa Oleoylethanolamide kumadziwika kuti kumangiriridwa ndi PPARα, yomwe imachepa ndi retinoid X receptor (RXR) ndikuyiyambitsa ngati chinthu champhamvu cholembera chomwe chimaphatikizidwa ndi kuphatikiza mphamvu ya homeostasis, lipid metabolism, autophagy, ndi kutupa. Zolinga zakumunsi.
Mbali
(1) Chiyero chachikulu: OEA imatha kupeza zinthu zoyeretsedwa kwambiri poyeretsa njira zopangira. Kuyeretsedwa kwakukulu kumatanthauza kukhalapo kwa bioavailability ndi zotsatira zochepa.
(2) Chitetezo: OEA yatsimikiziridwa kukhala yotetezeka kwa thupi la munthu.
(3) Kukhazikika: OEA ili ndi bata labwino ndipo imatha kusunga ntchito yake ndi zotsatira zake pansi pazigawo zosiyanasiyana ndi malo osungira.
(4) Yosavuta kuyamwa: OEA imatha kutengeka mwachangu ndi thupi la munthu ndikugawidwa kumagulu ndi ziwalo zosiyanasiyana.
Mapulogalamu
Oleoylethanolamide ndi chilengedwe cha ethanolamide lipid chomwe chimagwiritsidwa ntchito ngati chakudya chokonzekera komanso chowongolera kulemera kwa thupi mumitundu yosiyanasiyana ya vertebrate. Ndi metabolite ya oleic acid yomwe imapangidwa m'matumbo aang'ono amunthu. Oleylethanolamide (OEA) ndi molekyulu yomwe imayang'anira lipid metabolism ndi mphamvu homeostasis. Imamamatira ku PPAR Alpha receptors ndipo imathandizira kuwongolera zinthu zinayi: njala, mafuta amthupi, cholesterol ndi kulemera. PPAR Alpha imayimira peroxide proliferator-activated receptor alpha, ndipo bioactive lipid amide oleoylethanolamide (OEA) ili ndi zinthu zosiyanasiyana zapadera za homeostatic, kuphatikizapo ntchito zotsutsana ndi kutupa, kusintha kwa chitetezo cha mthupi, ndi antioxidant zotsatira.
