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mankhwala

Compound 7P wopanga ufa CAS No.: 1890208-58-8 99% chiyero min. kwa zowonjezera zowonjezera

Kufotokozera Kwachidule:

Compound 7p inasonyezedwa kuti ipangitse kukula kwa ma axon a GAP-43-positive mu chitsanzo cha nyama cha kuvulala kwa mitsempha ya optic, kutanthauza kuti ntchito ya neurite outgrowth ya 7p mu vitro imatanthawuza kulimbikitsanso kusinthika kwa axon mu vivo.


Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Kanema wa Zamalonda

Product Parameters

Dzina la malonda

Mtengo wa 7P

Dzina lina

Chigawo7P;2 - [(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide;

2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide

CAS No.

1890208-58-8

Mapangidwe a maselo

Chithunzi cha C22H23N3O5S

Kulemera kwa maselo

441.51

Chiyero

99.0%

Maonekedwe

White ufa

Kugwiritsa ntchito

Mankhwala a Nootropic

Chiyambi cha malonda

Compound 7P imatanthawuza chinthu china chamoyo chomwe chili ndi maatomu asanu ndi awiri a carbon. Mu organic chemistry, mpweya ndi chinthu chofunikira kwambiri chifukwa ukhoza kupanga mgwirizano wolimba ndi maatomu ena, kuphatikizapo maatomu a carbon, kupanga mamolekyu ovuta. Mamolekyuwa amatha kukhala ndi zinthu zosiyanasiyana komanso ntchito zosiyanasiyana, zomwe zimapangitsa kuti zinthu za carbon zikhale zomangira moyo. Mu zitsanzo za zinyama za kuvulala kwa mitsempha ya optic, 7p inasonyezedwa kuti ipangitse kukula kwa ma axon a GAP-43-positive, kutanthauza kuti ntchito ya kukula kwa neurite ya 7p mu vitro imatanthawuza kulimbikitsa kusinthika kwa axonal mu vivo. Compound 7P ufa ndi ufa woyera mpaka woyera wopangidwa ngati tandem pawiri kuti adziwe awiri-acting thromboxane receptor antagonist inhibitors. M'malo mwake, pawiri 7p idawonetsa kusankha kwa prostaglandin I2 synthase (PTGIS, CYP8A1) yokhudzana ndi thromboxane synthase (CYP5A1). Mankhwala a nootropic 7P ufa amalimbikitsa kukula kwa ma axon a Gap-43-positive, motero amalimbikitsa kusinthika kwa axonal m'thupi. Complex 7p yapamwamba kwambiri idapangidwa kuti izithandizira kulumikizana, kusintha malingaliro ndikuthandizira kuthana ndi kutopa. Imalepheretsanso kutulutsa okosijeni muubongo ndipo imathandizira kuthana ndi kuwonongeka kwa ubongo chifukwa chakumwa mowa.

Mbali

结构图

(1) Chiyero chachikulu: Compound 7P imatha kupeza zinthu zoyera kwambiri kudzera munjira zoyenga. Kuyeretsedwa kwakukulu kumatanthauza kukhalapo kwa bioavailability ndi zotsatira zochepa.

(2) Chitetezo: Compound 7P yatsimikiziridwa kuti ndi yotetezeka kwa thupi la munthu.

(3) Kukhazikika: Compound 7P ili ndi kukhazikika bwino ndipo imatha kusunga ntchito ndi zotsatira zake pansi pazigawo zosiyanasiyana ndi malo osungira.

Mapulogalamu

Compound 7p imakulitsa kukula kwa neurite kwa ma neuron otukuka omwe amachokera ku hippocampus, cerebral cortex, ndi retina ndipo imapangitsa kusinthika kwa mitsempha yamaso mumitundu yanyama yovulala kwa mitsempha ya optic. Zimathandiziranso kugwirizanitsa, zimathandizira kuwonongeka kwa ubongo chifukwa cha mowa, ndikuletsa okosijeni kuzungulira ubongo. Zimathandizanso kusintha maganizo komanso kuthana ndi kutopa.


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