Palmitoylethanolamide (PEA) wopanga ufa CAS No.: 544-31-0 99% chiyero min. kwa zowonjezera zowonjezera

Palmitoylethanolamide ndi molekyulu ya lipid messenger yomwe idapezeka koyamba kumapeto kwa 1950s. Ndi m'gulu la mankhwala otchedwa endocannabinoids, omwe ndi zinthu zachilengedwe zomwe zimagwirizana ndi dongosolo la endocannabinoid la thupi. Mosiyana ndi ma cannabinoids ena monga THC omwe amapezeka mu chomera cha cannabis, PEA sichitha kusokoneza maganizo ndipo sipanga zotsatira zosintha maganizo. Dongosolo la endocannabinoid (ECS) ndi netiweki yovuta ya zolandilira ndi endocannabinoids zomwe zimapezeka mthupi lonse. Zimagwira ntchito yofunika kwambiri pakuwongolera machitidwe osiyanasiyana amthupi, kuphatikiza malingaliro opweteka, kutupa, ndi malingaliro. PEA imagwira ntchito ngati ligand yokhazikika kwa cholandilira chapadera mkati mwa ECS yotchedwa peroxisome proliferator-activated receptor-α (PPAR-α). Poyambitsa cholandilira ichi, PEA imakhala ndi anti-inflammatory and analgesic effect. Kafukufuku akuwonetsa kuti Palmitoylethanolamide imatha kuthandizira kuthana ndi ululu wosatha, kuphatikizapo ululu wa neuropathic ndi kutupa. Zimagwira ntchito pochepetsa kutulutsidwa kwa zinthu zoyambitsa kutupa ndikuwongolera kuyambitsa kwa maselo a chitetezo chamthupi omwe amakhudzidwa ndi kuyankha kotupa. Mayesero angapo a zachipatala awonetsa mphamvu ya PEA pochepetsa kupweteka kwambiri komanso kupititsa patsogolo umoyo wa odwala omwe ali ndi ululu wopweteka wosiyanasiyana.