Palmitoylethanolamide (PEA) ndi mafuta acid amide omwe amapezeka mwachilengedwe omwe akopa chidwi cha ubwino wake pa thanzi. Mankhwalawa amapezeka m'maselo osiyanasiyana m'thupi lonse, ndipo kafukufuku akusonyeza kuti palmitamideethanol (PEA) imatha kuchepetsa kutupa, kuchepetsa ululu, komanso ingathandize thanzi la m'mimba ndikuchedwetsa ukalamba. Ikhoza kukhala ndi maubwino osiyanasiyana pa thanzi. Zotsatirazi zifufuza maubwino a palmitoylethanolamide (PEA) pa thanzi, momwe imagwirira ntchito pa thupi la munthu, komanso momwe mungapezere palmitoylethanolamide (PEA) yapamwamba kwambiri.
Kodi palmitoylethanolamide (PEA) ndi chiyani?
Palmitoylethanolamide (PEA) ndi mankhwala achilengedwe ofanana ndi endocannabinoid omwe amadziwika ndi mphamvu zake zosatha zochepetsera ululu komanso zoletsa kutupa. Kuwonjezera pa kupangidwa ndi thupi, PEA imapezeka muzakudya zosiyanasiyana kuphatikizapo: tchizi, mazira, nyama, mkaka, mtedza, ndi soya lecithin.
Kodi mukudziwa? Thupi likakumana ndi zinthu zovutitsa maganizo, monga kuvulala kapena kutupa, milingo ya PEA imasintha kuti isunge homeostasis ya maselo.
Kodi palmitoylethanolamide imakhudza bwanji thupi la munthu?
Asayansi sakumvetsa bwino momwe palmitoylethanolamide imagwirira ntchito. Komabe, tapita patsogolo kwambiri, chifukwa cha Pulofesa Rita Levi-Montalcini, yemwe mu 1992-1996 adafotokoza bwino momwe palmitoylethanolamide imagwirira ntchito. Kuyambira nthawi imeneyo, wapitiliza kuphunzira za zotsatira za palmitoylethanolamide pa ululu wa mitsempha ndi ziwengo.
Palmitoylethanolamide ikhoza kubweretsa zabwino zinayi zazikulu pa thanzi la anthu:
●Kuchepetsa kutupa.
●Chepetsani kuyambika kwa mast cell (allergy).
●Limbitsani ntchito ya dongosolo la hemp lachilengedwe.
●Yambitsani ma receptor enaake m'thupi.
Kodi PEA imagwira ntchito bwanji poletsa kutupa komanso kuletsa ululu?
Ubwino wa PEA pa thanzi umaphatikizapo zotsatira pa maselo oteteza thupi omwe amalamulira kutupa, makamaka muubongo. PEA ingathandize kuchepetsa kupanga zinthu zotupa. Komabe, PEA imagwira ntchito makamaka pa ma receptor pamaselo, omwe amalamulira mbali zosiyanasiyana za ntchito ya maselo. Ma receptor awa amatchedwa PPAR. PEA ndi mankhwala ena omwe amathandiza kuyambitsa PPAR amatha kuchepetsa ululu ndipo amathanso kuwonjezera kagayidwe kachakudya mwa kutentha mafuta, kuchepetsa triglycerides m'magazi, kuwonjezera cholesterol ya HDL m'magazi, kusintha kuwongolera shuga m'magazi, ndikuthandizira kuchepetsa thupi.
Ubwino wa Palmitoylethanolamide
Chifukwa cha mphamvu zake zochepetsa ululu komanso zotsutsana ndi kutupa, kafukufuku akusonyeza kuti PEA ingathandize ndi matenda osiyanasiyana okhudzana ndi ululu, monga fibromyalgia, sciatica, ndi osteoarthritis.
1. Kuchepetsa ululu ndi kutupa
Ululu wosatha ndi vuto lalikulu lomwe limavutitsa odwala padziko lonse lapansi, ndipo pamene anthu akukalamba, vutoli lidzakhala lofunika kwambiri. Chimodzi mwa ntchito za palmitoylethanolamide ndikuti zingathandize kuchepetsa ululu ndi kutupa. palmitoylethanolamide imagwirizana ndi ma CB1 ndi ma CB2 receptors, omwe ndi zigawo zofunika kwambiri za dongosolo la hemp la endogenous. Dongosololi limayang'anira kusunga homeostasis kapena kulinganiza bwino thupi.
Pakachitika kuvulala kapena kutupa, thupi limatulutsa mankhwala a hemp kuti lithandize kuwongolera chitetezo cha mthupi. Palmitoylethanolamide ingathandize kuwonjezera kuchuluka kwa hemp m'thupi, potero kuchepetsa ululu ndi kutupa.
Kuphatikiza apo, palmitoylethanolamide ingachepetse kutulutsidwa kwa mankhwala otupa ndikuchepetsa mayankho onse otupa amitsempha. Zotsatirazi zimapangitsa palmitoylethanolamide kukhala chida chothandiza kuwongolera ululu ndi mayankho otupa. Kafukufuku akuwonetsa kuti palmitoylethanolamide ingathandizenso pa ululu wa sciatica ndi matenda a carpal tunnel.
2. Matenda a Fibromyalgia
Kafukufuku wosiyanasiyana akusonyeza kuti PEA ingathandize kuchepetsa zizindikiro za fibromyalgia, matenda osatha amitsempha omwe amayambitsa ululu wofala. Ikagwiritsidwa ntchito ngati chowonjezera pa mankhwala achikhalidwe, kumwa PEA kumachepetsa ululu kwambiri ndipo kumawongolera moyo wabwino pakapita nthawi. Malinga ndi kafukufuku wina, kumwa PEA kwa miyezi itatu kumachepetsa kwambiri ululu mwa anthu omwe ali ndi fibromyalgia.
3. Kupweteka kwa msana
Kafukufuku woyamba akusonyeza kuti PEA ingathandize kwambiri pa ululu wa msana. Kafukufuku wofufuza wa mu 2017 adawonetsa kuti PEA idachepetsanso ululu kwa odwala omwe ali ndi vuto la opaleshoni ya msana yolephera.
Anthu omwe ali ndi vuto la sciatica, lomwe limayamba kuchokera pansi pa msana kupita pansi pa mwendo umodzi kapena yonse, angapezenso mpumulo atamwa PEA. Kafukufuku wochitidwa mwachisawawa, wosawoneka bwino, wolamulidwa ndi placebo adaphunzira zotsatira za PEA yochuluka komanso yotsika poyerekeza ndi placebo. Ululu unachepetsedwa ndi oposa 50% m'gulu la odwala omwe ali ndi mlingo waukulu. Ngakhale kuti PEA yocheperako sinapeze mpumulo wofanana ndi wa odwala omwe ali ndi mlingo waukulu, mlingo wonsewo unali wogwira mtima kwambiri kuposa placebo.
4. Matenda a nyamakazi
PEA ingakhale yothandiza kwa anthu omwe ali ndi osteoarthritis, matenda omwe amadziwika ndi kuwonongeka kwa cartilage ndi mafupa a mafupa. Ophunzira omwe adalandira PEA adawona kusintha kwakukulu mu Western Ontario ndi McMaster Universities Osteoarthritis Index (WOMAC) scores poyerekeza ndi gulu la placebo. WOMAC ndi mafunso opangidwa kuti awone momwe zinthu zilili ndi zizindikiro (monga kupweteka, kuuma, kugwira ntchito kwa thupi) mwa odwala omwe ali ndi osteoarthritis ya bondo ndi chiuno.
Kafukufuku wina wokhudza odwala omwe ali ndi ululu wa temporomandibular arthritic (TMJ) wokhudzana ndi osteoarthritis adawonetsa kuti kuwonjezera kwa PEA kunathandiza kwambiri kupweteka patatha masiku 14 poyerekeza ndi ibuprofen. Gulu lomwe linapatsidwa PEA kwa masiku 14 linawonetsa kusintha kwakukulu pakutsegula pakamwa kwambiri (muyeso wochepetsa ululu) kuposa gulu la ibuprofen.
5. Kupweteka kwa mitsempha
Kafukufuku woyambirira ndi mayeso a nyama akusonyeza kuti PEA ingathandize ndi ululu wa neuropathic (womwe umayamba chifukwa cha kuwonongeka kwa mitsempha yomwe imanyamula mauthenga pakati pa ubongo ndi msana), makamaka kwa anthu omwe ali ndi matenda a carpal tunnel syndrome, matenda a shuga, chemotherapy Anthu omwe ali ndi matenda a peripheral neuropathy, ululu wosatha wa m'chiuno, komanso ululu wokhudzana ndi sitiroko ndi multiple sclerosis. Mayeso ena azachipatala amafunika kuti adziwe momwe PEA imagwirira ntchito pothetsa ululu wa neuropathic.
6. Kukalamba Bwino
Kuchedwetsa ukalamba ndi cholinga chofunikira chomwe asayansi ambiri padziko lonse lapansi amatsatira. Palmitoylethanolamide imaonedwa ngati chowonjezera choletsa ukalamba chomwe chingathandize kuteteza maselo ku kuwonongeka kwa okosijeni, chomwe ndi chifukwa chachikulu cha ukalamba.
Maselo akakumana ndi zochita zambiri za free radicals, ma oxidative reaction amatha kuchitika, zomwe zimapangitsa kuti maselo afe msanga. Kudya zakudya zosapatsa thanzi, kusuta fodya, ndi zina zomwe zimayambitsa chilengedwe monga kuipitsidwa kwa mpweya kumawonjezeranso kuwonongeka kwa oxidative. Palmitoylethanolamide ikhoza kuletsa kuwonongeka kumeneku pochotsa ma free radicals ndikuchepetsa kutupa konse m'thupi.
Kuphatikiza apo, palmitoylethanolamide ethanol yawonetsedwa kuti imalimbikitsa kupanga collagen ndi mapuloteni ena ofunikira pakhungu. Chifukwa chake, imatha kuchepetsa mawonekedwe a makwinya ndi mizere yaying'ono, ikugwira ntchito ngati choteteza mkati mwa maselo.
Suzhou Myland Pharm & Nutrition Inc. ndi kampani yolembetsedwa ndi FDA yomwe imapereka ufa wa Palmitoylethanolamide (PEA) wapamwamba komanso woyera kwambiri.
Ku Suzhou Myland Pharm, tadzipereka kupereka zinthu zabwino kwambiri pamitengo yabwino kwambiri. Ufa wathu wa Palmitoylethanolamide (PEA) umayesedwa bwino kuti ukhale woyera komanso wamphamvu, zomwe zimakutsimikizirani kuti mumapeza chowonjezera chapamwamba chomwe mungachidalire. Kaya mukufuna kuthandiza thanzi la maselo, kulimbitsa chitetezo cha mthupi lanu, kapena kulimbitsa thanzi lonse, ufa wathu wa Palmitoylethanolamide (PEA) ndiye chisankho chabwino kwambiri.
Ndi zaka 30 zakuchitikira komanso kutsogoleredwa ndi ukadaulo wapamwamba komanso njira zabwino kwambiri zofufuzira ndi chitukuko, Suzhou Myland Pharm yapanga zinthu zosiyanasiyana zopikisana ndipo yakhala kampani yatsopano yowonjezera sayansi ya moyo, kupanga zinthu mwamakonda komanso kupanga zinthu.
Kuphatikiza apo, Suzhou Myland Pharm ndi kampani yodziwika bwino yopanga mankhwala yomwe ili ndi dzina la FDA. Zipangizo za kafukufuku ndi chitukuko cha kampaniyi, malo opangira mankhwala, ndi zida zowunikira ndi zamakono komanso zogwira ntchito zosiyanasiyana, ndipo zimatha kupanga mankhwala kuyambira mamiligalamu mpaka matani ambiri, komanso zimagwirizana ndi miyezo ya ISO 9001 ndi zomwe zimapangidwa ndi GMP.
Chodzikanira: Nkhaniyi ndi yongofuna kudziwa zambiri ndipo siyenera kuonedwa ngati upangiri uliwonse wa zachipatala. Zina mwa zomwe zili mu blog iyi zimachokera pa intaneti ndipo si zaukadaulo. Webusaitiyi ili ndi udindo wosankha, kupanga ndi kusintha nkhani zokha. Cholinga chopereka zambiri sichikutanthauza kuti mukugwirizana ndi malingaliro ake kapena kutsimikizira kuti zomwe zili mkati mwake ndi zoona. Nthawi zonse funsani katswiri wa zaumoyo musanagwiritse ntchito zowonjezera zilizonse kapena kusintha njira yanu yazaumoyo.
Nthawi yotumizira: Sep-13-2024
