Zomwe muyenera kudziwa zokhudza ukalamba ndi njira zomwe mungatenge kuti muchepetse kukalamba

Pamene anthu akukalamba, ambiri amafunafuna njira zochepetsera ndondomekoyi ndikukhalabe ndi maonekedwe aunyamata ndi nyonga. Pali njira ndi njira zosiyanasiyana zomwe zingagwiritsidwe ntchito kuthandizira kuchepetsa ukalamba ndikulimbikitsa thanzi labwino ndi thanzi.

Kafukufuku waposachedwa akuwonetsa kuti kukalamba sikungochitika pang'onopang'ono, komanso kumayamba nthawi inayake pakati pa zaka 44 ndi 60.

Kuyambira kumayambiriro kwa zaka za m'ma 40, kagayidwe kake ka lipid ndi mowa kamasintha, pamene impso zanu, kagayidwe kake kagayidwe kake, ndi chitetezo cha mthupi zimayamba kuchepa pafupifupi zaka 60. wakale.

Kafukufukuyu adaphatikizanso anthu aku California a 108 azaka zapakati pa 25 mpaka 75, ndipo kafukufuku wochulukirapo akufunika kuti atsimikizire zomwe zapeza. Komabe, zomwe zapezazi zingapangitse kuyesedwa kwatsopano kwa matenda ndi njira zopewera matenda okhudzana ndi ukalamba.

Kukhala ndi moyo wautali sikutanthauza kukhala ndi moyo wathanzi kapena wokangalika. Malinga ndi wolemba wamkulu wa kafukufukuyu Dr. Michael Snyder, mkulu wa Center for Genomics and Personalized Medicine ku yunivesite ya Stanford, kwa anthu ambiri, "thanzi" lawo lapakati - nthawi yomwe amakhala ndi thanzi labwino - ndi yotalika kuposa momwe moyo wawo uliri waufupi. 11-15 zaka.

Midlife ndi yofunika kwambiri pa ukalamba wathanzi

Kafukufuku wam'mbuyomu wasonyeza kuti thanzi lanu m'zaka zapakati (nthawi zambiri zaka zapakati pa 40 ndi 65) zimagwira ntchito yofunika kwambiri pa thanzi lanu m'tsogolomu. Kafukufuku wa 2018 mu nyuzipepala ya Nutrition adagwirizanitsa zinthu zinazake za moyo wa zaka zapakati, monga kulemera kwa thanzi, kukhala ochita masewera olimbitsa thupi, kudya zakudya zabwino komanso kusasuta fodya, kuti ukhale ndi thanzi labwino pamene ukalamba. 2

Lipoti lofalitsidwa mu nyuzipepala ya 2020 likuwonetsanso kuti midlife ndi nthawi yofunika kwambiri yosinthira thanzi laubongo. Kuwongolera kuthamanga kwa magazi ndikukhalabe ndi anthu, kuzindikira komanso kuchita masewera olimbitsa thupi panthawiyi kungathandize kuchepetsa chiopsezo cha dementia m'tsogolomu, lipotilo linatero.

Kafukufuku watsopanoyu akuwonjezera gawo la kafukufuku waumoyo komanso kuwunikira kufunikira kokhala ndi zizolowezi zina za moyo m'moyo.

Kenneth Boockvar, MD, mkulu wa Center for Integrated Research on Aging ku yunivesite ya Alabama anati: Birmingham. ” koma sanalowe nawo m’phunzirolo.

Anawonjezeranso kuti kunali koyambirira kwambiri kuti apange malingaliro enieni malinga ndi kafukufuku watsopano, koma kuti anthu omwe akufuna kukhala ndi thanzi labwino m'zaka zawo za 60 ayenera kuyamba kumvetsera zakudya zawo ndi moyo wawo m'zaka za 40 ndi 50.

Kukalamba sikungapeweke, koma kusintha kwa moyo kumatha kukulitsa moyo wathanzi

Kafukufuku watsopano apeza kuti mamolekyu ndi tizilombo tating'onoting'ono tomwe timakhala tikukalamba timachepa panthawi inayake ya moyo, koma kufufuza kwamtsogolo ndikofunikira kuti muwone ngati kusintha komweko kwa maselo kumachitika m'magulu osiyanasiyana.

"Tikufuna kusanthula anthu ambiri m'dziko lonselo kuti tiwone ngati zomwe tikuwona zikugwira ntchito kwa aliyense - osati anthu a ku Bay Area," adatero Snyder. "Tikufuna kupenda kusiyana pakati pa amuna ndi akazi. Akazi amakhala ndi moyo wautali ndipo tikufuna kumvetsa chifukwa chake."

Kukalamba sikungapeweke, koma kusintha kwina kwa moyo kungathandize kuchepetsa chiopsezo cha matenda okhudzana ndi ukalamba. Komabe, zinthu zina zambiri monga chilengedwe, kukhazikika kwachuma, chithandizo chamankhwala ndi mwayi wamaphunziro zimakhudzanso zotsatira za ukalamba wathanzi ndipo zimakhala zovuta kuti anthu aziwongolera.

Anthu amatha kusintha moyo waung'ono monga kukhalabe hydrated kuti akhalebe ndi thanzi la impso, kumanga minofu ndi maphunziro olemera komanso kumwa mankhwala a kolesterolini ngati LDL cholesterol ikukwera, Snyder adanena.

Ananenanso kuti: “Izi sizingathetse ukalamba, koma zichepetsa mavuto omwe timawaona komanso kuthandiza kuti anthu azikhala ndi moyo wathanzi.

Kodi tingatani kuti tichedwetse kukalamba?

Chimodzi mwa zinthu zofunika kwambiri zochepetsera ukalamba ndi kukhala ndi moyo wathanzi. Izi zikuphatikizapo kudya zakudya zopatsa thanzi zomwe zili ndi zipatso, ndiwo zamasamba, mbewu zonse ndi zomanga thupi. Kupewa zakudya zowonongeka, shuga wambiri, ndi mafuta osayenera kungathandize kuchepetsa kutupa m'thupi ndikuthandizira thanzi labwino. Kukhalabe ndi hydrate mwa kumwa madzi ambiri ndikofunikiranso kuti khungu ndi ziwalo zikhale zathanzi.

Kuchita masewera olimbitsa thupi nthawi zonse ndi chinthu china chofunika kwambiri pa moyo wathanzi ndipo kungathandize kuchepetsa ukalamba. Zochita zolimbitsa thupi zimathandizira kupititsa patsogolo thanzi la mtima, kukhalabe ndi minofu, komanso kuthandizira kusuntha konse ndi kusinthasintha. Kuchita nawo zinthu monga kuyenda, kusambira, yoga kapena kuchita masewera olimbitsa thupi kungathandize thupi lanu kuti liwoneke laling'ono komanso lamphamvu.

Kuwonjezera pa zakudya ndi masewera olimbitsa thupi, kuyendetsa kupanikizika n'kofunika kuti muchepetse ukalamba. Kupsinjika kwanthawi yayitali kumatha kukhala ndi zotsatira zoyipa m'thupi, zomwe zimayambitsa kutupa komanso kufooka kwa chitetezo chamthupi. Kuchita njira zochepetsera kupsinjika maganizo monga kusinkhasinkha, kupuma mozama, kapena kulingalira kungathandize kulimbikitsa kupumula ndi kukhala ndi thanzi labwino.

Mbali ina yofunika yochepetsera ukalamba ndiyo kugona mokwanira. Kugona n’kofunika kwambiri kuti thupi likhale lokonzeka komanso kuti likhalenso ndi moyo, ndipo kusagona bwino kungayambitse kukalamba msanga. Kukhazikitsa nthawi yogona nthawi zonse ndikupanga nthawi yogona yopumula kungathandize kukonza kugona bwino komanso kukhala ndi thanzi labwino.

Kuwonjezera pa zochitika za moyo, pali mankhwala osiyanasiyana omwe angathandize kuchepetsa ukalamba. Izi zingaphatikizepo njira zosamalira khungu, zodzoladzola, ndi chithandizo chamankhwala. Kugwiritsa ntchito mafuta oteteza ku dzuwa ndi kunyowetsa khungu lanu kungathandize kuti dzuwa lisawonongeke komanso kuti likhalebe lachinyamata. Njira zodzikongoletsera monga Botox, fillers, ndi laser treatment zingathandizenso kuchepetsa maonekedwe a makwinya ndi mizere yabwino.

Kuonjezera apo, pali mankhwala ena oletsa kukalamba omwe alipo omwe angathandize thanzi labwino komanso nyonga. Zina mwazowonjezera zomwe zili ndi umboni wambiri wasayansi wothandizira gawo lawo pakuwongolera thanzi la mitochondrial komanso kuchedwetsa kukalamba ndi zotsogola za NAD + ndi urolithin A.

NAD + zowonjezera

Kumene kuli mitochondria, pali NAD+ (nicotinamide adenine dinucleotide), molekyulu yofunikira pakukulitsa kupanga mphamvu. NAD + mwachilengedwe imatsika ndi zaka, zomwe zikuwoneka kuti zikugwirizana ndi kuchepa kwa zaka zokhudzana ndi ntchito ya mitochondrial.

Kafukufuku akuwonetsa kuti pokulitsa NAD +, mutha kupititsa patsogolo mphamvu ya mitochondrial ndikupewa kupsinjika kokhudzana ndi ukalamba. Zowonjezera zowonjezera za NAD + zitha kupititsa patsogolo magwiridwe antchito a minofu, thanzi laubongo, komanso kagayidwe kachakudya kwinaku akulimbana ndi matenda a neurodegenerative. Kuphatikiza apo, amachepetsa kunenepa, amakulitsa chidwi cha insulin, komanso amawongolera milingo ya lipid, monga kutsitsa LDL cholesterol.

Coenzyme Q10

Monga NAD +, coenzyme Q10 (CoQ10) imagwira ntchito mwachindunji komanso yofunika kwambiri pakupanga mphamvu za mitochondrial. Monga astaxanthin, CoQ10 imachepetsa kupsinjika kwa okosijeni, kutulutsa mphamvu kwa mitochondrial komwe kumakulirakulira pamene mitochondria ilibe thanzi. Kuonjezera CoQ10 kumachepetsa chiopsezo cha matenda a mtima, sitiroko ndi imfa. Poganizira kuti CoQ10 imatsika ndi zaka, kuwonjezera ndi CoQ10 kungapereke ubwino wa moyo wautali kwa okalamba.

Urolithin A

Urolithin A (UA) amapangidwa ndi mabakiteriya athu am'matumbo atadya ma polyphenols omwe amapezeka muzakudya monga makangaza, sitiroberi, ndi mtedza. Kuphatikizika kwa UA mu mbewa zazaka zapakati kumayambitsa ma sirtuins ndikuwonjezera NAD + ndi ma cell amphamvu. Chofunika kwambiri, UA yasonyezedwa kuti imachotsa mitochondria yowonongeka kuchokera ku minofu yaumunthu, motero imalimbitsa mphamvu, kukana kutopa, ndi masewera olimbitsa thupi. Chifukwa chake, kuphatikizika kwa UA kumatha kukulitsa moyo wawo polimbana ndi ukalamba wa minofu.

Spermidine

Monga NAD + ndi CoQ10, spermidine ndi molekyulu yochitika mwachilengedwe yomwe imachepa ndi zaka. Mofanana ndi UA, spermidine imapangidwa ndi mabakiteriya athu a m'matumbo ndipo imayambitsa mitophagy - kuchotsedwa kwa mitochondria yopanda thanzi, yowonongeka. Kafukufuku wa mbewa akuwonetsa kuti spermidine supplementation ingateteze ku matenda a mtima ndi ukalamba wa amayi. Kuphatikiza apo, zakudya za spermidine (zopezeka muzakudya zosiyanasiyana kuphatikiza soya ndi mbewu) zimathandizira kukumbukira mbewa. Kafukufuku wochulukirapo akufunika kuti adziwe ngati zomwe zapezazi zitha kutsatiridwanso mwa anthu.

Suzhou Myland Pharm & Nutrition Inc. ndi wopanga olembetsedwa ndi FDA yemwe amapereka ufa wapamwamba kwambiri komanso woyeretsedwa kwambiri wa urolithin A.

Ku Suzhou Myland Pharm tadzipereka kupereka zinthu zapamwamba kwambiri pamitengo yabwino kwambiri. Urolithin A ufa wathu umayesedwa mwamphamvu kuti ukhale woyera ndi potency, kuonetsetsa kuti mumapeza chowonjezera chapamwamba chomwe mungakhulupirire. Kaya mukufuna kuthandizira thanzi la ma cell, kulimbikitsa chitetezo chamthupi kapena kukulitsa thanzi labwino, Urolithin A ufa wathu ndiye chisankho chabwino kwambiri.

Ndi zaka 30 zachidziwitso komanso motsogozedwa ndiukadaulo wapamwamba komanso njira zokongoletsedwa bwino za R&D, Suzhou Myland Pharm yapanga zinthu zambiri zampikisano ndikukhala kampani yotsogola ya sayansi ya moyo, kaphatikizidwe kazinthu ndi ntchito zopanga.

Kuphatikiza apo, Suzhou Myland Pharm ndiwopanganso zolembedwa ndi FDA. Zothandizira zamakampani za R&D, malo opangira, ndi zida zowunikira ndi zamakono komanso zimagwira ntchito zambiri, ndipo zimatha kupanga mankhwala kuchokera ku ma milligrams mpaka matani mu sikelo, ndikutsatira miyezo ya ISO 9001 ndi mafotokozedwe a GMP.