Zakudya 4 Zapamwamba Zotsutsana ndi Ukalamba Zothandizira Thanzi la Mitochondrial: Ndi Ziti Zamphamvu Kwambiri?

Asayansi apeza kuti pamene tikukalamba, mitochondria yathu imachepa pang'onopang'ono ndipo imapanga mphamvu zochepa. Izi zingayambitse matenda okhudzana ndi ukalamba monga matenda a mitsempha, matenda a mtima, ndi zina zotero.

Urolithin A

Urolithin A ndi chinthu chachilengedwe chomwe chili ndi mphamvu zotsutsana ndi ma antioxidants komanso zoletsa kufalikira kwa maselo. Akatswiri azakudya ochokera ku Nova Southeastern University ku United States apeza kuti kugwiritsa ntchito urolithin A ngati njira yochepetsera ukalamba kungachedwetse kukalamba ndikuletsa kukula kwa matenda okhudzana ndi ukalamba.
Urolithin A (UA) imapangidwa ndi mabakiteriya athu am'mimba mutadya ma polyphenols omwe amapezeka muzakudya monga mapomegranate, sitiroberi, ndi mtedza. Kuwonjezera UA kwa mbewa zapakati kumayatsa ma sirtuins ndikuwonjezera mphamvu za NAD+ ndi maselo. Chofunika kwambiri, UA yawonetsedwa kuti imachotsa mitochondria yowonongeka m'minofu ya anthu, motero imawonjezera mphamvu, kukana kutopa, komanso magwiridwe antchito amasewera. Chifukwa chake, kuwonjezera UA kumatha kukulitsa moyo wa munthu polimbana ndi kukalamba kwa minofu.
Urolithin A siichokera ku zakudya mwachindunji, koma mankhwala monga ellagic acid ndi ellagitannins omwe amapezeka mu mtedza, mapomegranate, mphesa ndi zipatso zina amapanga urolithin A atasinthidwa ndi tizilombo toyambitsa matenda m'matumbo.

Spermidine

Spermidine ndi mtundu wachilengedwe wa polyamine womwe walandiridwa m'zaka zaposachedwa chifukwa cha kuthekera kwake kowonjezera moyo ndikuwonjezera nthawi yaumoyo. Monga NAD+ ndi CoQ10, spermidine ndi molekyulu yobadwa mwachibadwa yomwe imachepa ndi ukalamba. Mofanana ndi UA, spermidine imapangidwa ndi mabakiteriya athu am'mimba ndipo imayambitsa mitophagy - kuchotsa mitochondria yosauka komanso yowonongeka. Kafukufuku wa mbewa akuwonetsa kuti kuwonjezera spermidine kungateteze ku matenda a mtima ndi ukalamba wobereka wa akazi. Kuphatikiza apo, spermidine yazakudya (yomwe imapezeka muzakudya zosiyanasiyana kuphatikiza soya ndi tirigu) yathandiza kukumbukira kukumbukira mwa mbewa. Kafukufuku wowonjezereka akufunika kuti adziwe ngati zomwe zapezekazi zitha kubwerezedwanso mwa anthu.
Kukalamba kwabwinobwino kumachepetsa kuchuluka kwa mitundu yachilengedwe ya umuna m'thupi, malinga ndi kafukufuku wofalitsidwa mu Scientific Reports ndi ofufuza ku Kyoto Prefectural University of Medicine ku Japan. Komabe, izi sizinawonekere mwa anthu opitirira zaka 100;
Spermidine ingathandize kuti munthu asamachite zinthu zosayenera.
Zakudya zomwe zili ndi umuna wambiri zimaphatikizapo: zakudya za tirigu wonse, kelp, bowa wa shiitake, mtedza, bracken, purslane, ndi zina zotero.

curcumin
Curcumin ndi chinthu chogwira ntchito mu turmeric chomwe chili ndi mphamvu zotsutsana ndi kutupa komanso zotsutsana ndi antioxidant.
Akatswiri a zamoyo ochokera ku Polish Academy of Sciences apeza kuti curcumin imatha kuchepetsa zizindikiro za ukalamba ndikuchedwetsa kupita patsogolo kwa matenda okhudzana ndi ukalamba omwe maselo okalamba amakhudzidwa mwachindunji, motero amatalikitsa moyo wawo.
Kuwonjezera pa turmeric, zakudya zomwe zili ndi curcumin yambiri ndi monga: ginger, adyo, anyezi, tsabola wakuda, mpiru ndi curry.

Zowonjezera za NAD+
Kumene kuli mitochondria, pali NAD+ (nicotinamide adenine dinucleotide), molekyulu yofunikira kuti pakhale mphamvu zambiri. NAD+ imachepa mwachibadwa ndi ukalamba, zomwe zimawoneka kuti zikugwirizana ndi kuchepa kwa ntchito ya mitochondrial chifukwa cha ukalamba. Ichi ndi chimodzi mwa zifukwa zomwe zidapangitsa kuti zolimbikitsira za NAD+ monga NR (Nicotinamide Ribose) zipangidwe kuti zibwezeretse milingo ya NAD+.
Kafukufuku akuwonetsa kuti polimbikitsa NAD+, NR imatha kukulitsa kupanga mphamvu za mitochondrial ndikuletsa kupsinjika komwe kumachitika chifukwa cha ukalamba. Zakudya zowonjezera za NAD+ zitha kusintha magwiridwe antchito a minofu, thanzi la ubongo, komanso kagayidwe kachakudya pomwe zitha kulimbana ndi matenda owononga mitsempha. Kuphatikiza apo, zimachepetsa kunenepa, zimathandizira kukhudzidwa kwa insulin, komanso zimabwezeretsa kuchuluka kwa mafuta m'thupi, monga kuchepetsa cholesterol ya LDL.