Asayansi apeza kuti tikamakalamba, mitochondria yathu imachepa pang'onopang'ono ndikupanga mphamvu zochepa. Izi zingayambitse matenda okhudzana ndi ukalamba monga matenda a neurodegenerative, matenda a mtima, ndi zina.
Urolithin A
Urolithin A ndi metabolite yachilengedwe yokhala ndi antioxidant komanso antiproliferative zotsatira. Akatswiri a Nutritionists ochokera ku Nova Southeastern University ku United States apeza kuti kugwiritsa ntchito urolithin A monga njira yazakudya kungachedwetse ukalamba ndikuletsa kukula kwa matenda okhudzana ndi ukalamba.
Urolithin A (UA) amapangidwa ndi mabakiteriya athu am'matumbo atadya ma polyphenols omwe amapezeka muzakudya monga makangaza, sitiroberi, ndi mtedza. Kuphatikizika kwa UA kwa mbewa zazaka zapakati kumayambitsa ma sirtuins ndikuwonjezera NAD + ndi mphamvu zama cell. Chofunika kwambiri, UA yasonyezedwa kuti imachotsa mitochondria yowonongeka kuchokera ku minofu yaumunthu, motero imalimbitsa mphamvu, kukana kutopa, ndi masewera olimbitsa thupi. Chifukwa chake, kuphatikizika kwa UA kumatha kukulitsa moyo wawo polimbana ndi ukalamba wa minofu.
Urolithin A sichichokera ku zakudya, koma mankhwala monga ellagic acid ndi ellagitannins omwe ali mu mtedza, makangaza, mphesa ndi zipatso zina zidzatulutsa urolithin A atapangidwa ndi tizilombo toyambitsa matenda.
Spermidine
Spermidine ndi mawonekedwe achilengedwe a polyamine omwe adalandira chidwi m'zaka zaposachedwa chifukwa cha kuthekera kwake kukulitsa moyo ndikuwonjezera thanzi. Monga NAD + ndi CoQ10, spermidine ndi molekyulu yochitika mwachilengedwe yomwe imachepa ndi zaka. Mofanana ndi UA, spermidine imapangidwa ndi mabakiteriya athu a m'matumbo ndipo imayambitsa mitophagy - kuchotsedwa kwa mitochondria yopanda thanzi, yowonongeka. Kafukufuku wa mbewa akuwonetsa kuti spermidine supplementation ingateteze ku matenda a mtima ndi ukalamba wa amayi. Kuphatikiza apo, zakudya za spermidine (zopezeka muzakudya zosiyanasiyana kuphatikiza soya ndi mbewu) zimathandizira kukumbukira mbewa. Kafukufuku wochulukirapo akufunika kuti adziwe ngati zomwe zapezazi zitha kutsatiridwanso mwa anthu.
Kukalamba koyenera kumachepetsa kuchuluka kwa mitundu yachilengedwe ya spermidine m'thupi, malinga ndi kafukufuku wofalitsidwa mu Scientific Reports ndi ofufuza a Kyoto Prefectural University of Medicine ku Japan. Komabe, chodabwitsa ichi sichinawonedwe mwazaka zana;
Spermidine imatha kulimbikitsa autophagy.
Zakudya zokhala ndi ma spermidine ambiri zimaphatikizapo: zakudya za tirigu, kelp, bowa wa shiitake, mtedza, bracken, purslane, etc.
curcumin
Curcumin ndi mankhwala omwe ali mu turmeric omwe ali ndi anti-inflammatory and antioxidant properties.
Akatswiri ofufuza zamoyo kuchokera ku Polish Academy of Sciences apeza kuti curcumin ikhoza kuchepetsa zizindikiro za ukalamba ndikuchedwetsa kufalikira kwa matenda okhudzana ndi ukalamba momwe maselo a senescent amakhudzidwa mwachindunji, motero amatalikitsa moyo.
Kuwonjezera pa turmeric, zakudya zomwe zili ndi curcumin zimaphatikizapo: ginger, adyo, anyezi, tsabola wakuda, mpiru ndi curry.
NAD + zowonjezera
Kumene kuli mitochondria, pali NAD+ (nicotinamide adenine dinucleotide), molekyulu yofunikira pakukulitsa kupanga mphamvu. NAD + mwachilengedwe imatsika ndi zaka, zomwe zikuwoneka kuti zikugwirizana ndi kuchepa kwa zaka zokhudzana ndi ntchito ya mitochondrial. Ichi ndi chimodzi mwazifukwa zomwe NAD + zolimbitsa thupi monga NR (Nicotinamide Ribose) zidapangidwa kuti zibwezeretse milingo ya NAD +.
Kafukufuku akuwonetsa kuti polimbikitsa NAD+, NR imatha kupititsa patsogolo mphamvu ya mitochondrial ndikuletsa kupsinjika kokhudzana ndi ukalamba. Zowonjezera zowonjezera za NAD + zitha kupititsa patsogolo magwiridwe antchito a minofu, thanzi laubongo, komanso kagayidwe kachakudya kwinaku akulimbana ndi matenda a neurodegenerative. Kuphatikiza apo, amachepetsa kunenepa, amakulitsa chidwi cha insulin, komanso amawongolera milingo ya lipid, monga kutsitsa LDL cholesterol.
Nthawi yotumiza: Jul-24-2024
