7,8-Dihydroxyflavone ndi chinthu chopangidwa mwachilengedwe chomwe chimapezeka muzomera chomwe chapeza chidwi chachikulu pazabwino zake pakugwira ntchito kwaubongo ndi kukumbukira. Flavone iyi ndi ya gulu la mankhwala otchedwa flavonoids, omwe amadziwika chifukwa cha antioxidant ndi anti-inflammatory properties. Kafukufuku wasonyeza kuti 7,8-dihydroxyflavone ikhoza kukhala ndi zotsatira zabwino zambiri paubongo.
7,8-Dihydroxyflavone ndi gulu lamphamvu komanso losinthasintha la banja la flavonoid. Flavonoids ndi zinthu zachilengedwe zomwe zimagawidwa kwambiri muzomera ndipo zimagwira ntchito yofunika kwambiri pazachilengedwe zosiyanasiyana. Chimodzi mwazinthu zochititsa chidwi za 7,8-dihydroxyflavone ndi kuthekera kwake kolumikizana ndikuwongolera mapuloteni ndi michere m'thupi, zomwe zadzutsa chidwi kwambiri ndi asayansi.
Kafukufuku wasonyeza kuti 7,8-dihydroxyflavone ili ndi ubwino wathanzi, wokhala ndi antioxidant, anti-inflammatory and neuroprotective properties. Pakati pawo, mphamvu ya antioxidant ya 7,8-dihydroxyflavone imathandizira kuti iwononge ma radicals aulere m'thupi komanso kupewa kupsinjika kwa okosijeni kumayambitsa kuwonongeka kwa maselo ndi matenda osiyanasiyana. Kafukufuku wopangidwa mpaka pano pa 7,8-dihydroxyflavones ndi wolimbikitsa, koma kafukufuku wochulukirapo akufunika kuti adziwe mphamvu ndi chitetezo cha 7,8-dihydroxyflavones kuti agwiritsidwe ntchito mwa anthu. Komabe, chigawo cha flavonoid ichi chimakhala ndi lonjezo lalikulu ngati chowonjezera pazakudya kapena mankhwala osokoneza bongo m'tsogolomu.
7,8-Dihydroxyflavone ndi mankhwala achilengedwe, omwe amadziwikanso kuti 7,8-DHF, omwe alandira chidwi kwambiri m'zaka zaposachedwa chifukwa cha ubwino wake pa thanzi laumunthu.
Chomera chopezeka mwachilengedwechi ndi cha banja la flavonoid ndipo chimapezeka muzomera zosiyanasiyana, kuphatikiza muzu wa Scutellaria baikalensis.
1. Kupititsa patsogolo chidziwitso
Kafukufuku akuwonetsa kuti chigawochi chimagwira ntchito ngati TrkB agonist, kutanthauza kuti imayambitsa ma receptor a TrkB muubongo. Ma receptor awa ndi omwe ali ndi udindo wopititsa patsogolo kukula ndi kupulumuka kwa ma neuron, komanso kupititsa patsogolo pulasitiki ya synaptic - kuthekera kwaubongo kusintha ndikusintha. Polimbikitsa ma receptor a TrkB, 7,8-dihydroxyflavone yawonetsedwa kuti imathandizira kukumbukira komanso kuzindikira. Izi zimapangitsa kukhala chithandizo chothandizira kuchiza matenda a neurodegenerative monga matenda a Alzheimer's.
2. Antidepressant zotsatira
Mwa kuyambitsa ma receptor a TrkB, gululi limalimbikitsa kukula kwa ma neuron atsopano mu hippocampus, gawo laubongo lomwe limakhudzidwa ndi kuwongolera maganizo. Kafukufuku wa zinyama awonetsa kuti 7,8-dihydroxyflavone imatha kuchepetsa kukhumudwa komanso kukulitsa kukana kupsinjika. Zotsatirazi zikusonyeza kuti mankhwalawa atha kugwiritsidwa ntchito ngati njira yachilengedwe yolimbana ndi kupsinjika maganizo.
3. Anti-yotupa katundu ndi antioxidant mphamvu
7,8-Dihydroxyflavone ndi antioxidant wamphamvu yomwe imathandiza kuteteza maselo ku nkhawa ya okosijeni yomwe imayambitsidwa ndi ma free radicals. Chitetezo chimenechi chimachepetsa chiopsezo cha matenda aakulu komanso chimachepetsa ukalamba.
Kutupa kwaubongo kungathandize kuti pakhale chitukuko ndi kufalikira kwa matenda osiyanasiyana amisempha, kuphatikizapo matenda a Parkinson ndi multiple sclerosis. Kafukufuku akuwonetsa kuti 7,8-DHF ili ndi anti-inflammatory properties zomwe zimathandiza kuchepetsa kutupa mu ubongo ndi kuteteza neurodegeneration. Poletsa kupanga mamolekyu oletsa kutupa, chigawocho chikhoza kukhala ndi mphamvu yochepetsera zizindikiro ndi kuchepetsa kukula kwa matenda ofooketsawa.
4. Ali ndi Mphamvu Yochizira Matenda a Nkhawa
Kafukufuku wa zinyama awonetsa kuti chigawochi chikhoza kuchepetsa khalidwe la nkhawa poyambitsa ma TrkB receptors mu amygdala, dera la ubongo lomwe limakhudzidwa ndi mantha ndi nkhawa. Posintha ntchito ya ma receptor awa, 7,8-dihydroxyflavones ikhoza kupereka njira yachilengedwe komanso yothandiza kuthana ndi nkhawa popanda zotsatirapo zomwe zimagwirizanitsidwa ndi mankhwala achikhalidwe odana ndi nkhawa.
Tisanayang'ane pazakudya, tiyeni timvetsetse kuti 7,8-dihydroxyflavone ndi chiyani. Ndi flavonoid yopezeka mwachilengedwe yomwe ili m'gulu la flavonoids. Flavonoids ndi mankhwala opangidwa ndi zomera omwe amadziwika kuti ali ndi antioxidant, omwe amathandiza kuteteza maselo ku ma radicals ovulaza.
Tsopano, tiyeni tiwone zakudya zina zomwe zili ndi kuchuluka kwa 7,8-dihydroxyflavone:
1. Zipatso za citrus
Chimodzi mwazinthu zabwino kwambiri za 7,8-dihydroxyflavones ndi zipatso za citrus monga malalanje, mandimu, manyumwa ndi mandimu. Zipatsozi sizingokhala ndi vitamini C, komanso zimakhala ndi flavonoids zosiyanasiyana, kuphatikizapo 7,8-dihydroxyflavone.
2. Zipatso
Zipatso monga blueberries, sitiroberi, raspberries, ndi mabulosi akuda amadziwika chifukwa chokhala ndi antioxidant. Zipatso zokomazi zilinso gwero labwino kwambiri la 7,8-dihydroxyflavone, kukupatsirani maubwino owirikiza athanzi.
3. Chokoleti Wakuda
Nkhani yabwino kwa okonda chokoleti! Chokoleti chakuda, makamaka chokhala ndi koko wambiri, chimakhala ndi 7,8-dihydroxyflavonoids yambiri. Komabe, sankhani mitundu yokhala ndi shuga wocheperako kuti mupeze phindu lonse.
4. Tiyi wobiriwira
Kuphatikiza pa kukhala chakumwa chodziwika bwino, tiyi wobiriwira alinso ndi flavonoids, kuphatikiza 7,8-dihydroxyflavone. Kumwa tiyi wobiriwira nthawi zonse kumatha kukulitsa madyedwe anu a antioxidant ndikuthandizira thanzi lanu lonse.
5. Soya
Ngati mukufuna chomera cha 7,8-dihydroxyflavone, soya ndi chisankho chabwino kwambiri. Sikuti ali ndi mapuloteni okha, komanso amakhala ndi flavonoids zosiyanasiyana zomwe zimathandiza kuti zikhale zopindulitsa.
6. Zamasamba zobiriwira
Zamasamba monga kale, sipinachi, ndi broccoli sizongokhala zochepa chabe, komanso zimakhala ndi antioxidants. Masamba amasamba awa ndi magwero abwino kwambiri a 7,8-dihydroxyflavone, komanso zakudya zina zofunika.
7. Vinyo wofiira
Zikomo! Kumwa vinyo wofiira pang'ono kumakhala ndi mtundu wa flavonoid wotchedwa resveratrol, womwe umaphatikizapo 7,8-dihydroxyflavone. Kapangidwe kameneka kakuganiziridwa kuti kamathandizira pamtima phindu logwirizana ndi kumwa vinyo wofiira pang'ono.
Kuphatikizira zakudya izi muzakudya zanu kumatha kukupatsirani zabwino zambiri zokhudzana ndi 7,8-dihydroxyflavone.
7,8-Dihydroxyflavone, yomwe imadziwikanso kuti DHF kapena baicalein, ndi flavonoid yopezeka mwachilengedwe yomwe imapezeka muzomera zosiyanasiyana, kuphatikiza muzu wa Scutellaria baikalensis. Pagululi lalandira chidwi kwambiri m'zaka zaposachedwa chifukwa cha mapindu ake azaumoyo komanso machiritso. Komabe, poganizira za chitetezo cha chinthu chilichonse, ndikofunikira kufufuza umboni wa sayansi womwe ulipo. Ndiye, 7,8-dihydroxyflavone ndi yotetezeka?
Pankhani ya chitetezo chake, kafukufuku wochepa wachitika pakugwiritsa ntchito mwachindunji kwa anthu a 7,8-dihydroxyflavone. Chifukwa chake, kunena motsimikiza za chitetezo chake ndizovuta. Komabe, maphunziro a zinyama apereka chidziwitso chofunikira pazachiwopsezo chake. Mitundu yosiyanasiyana ya nyama sinanene zotsatirapo zoyipa pambuyo pa kuwongolera kwa DHF, ngakhale pamilingo yayikulu. Izi zikusonyeza kuti 7,8-dihydroxyflavone ikhoza kulekerera bwino, osachepera mkati mwa magawo omwe amaphunzira.
Komabe, kusamala kuyenera kuchitidwa popanga malingaliro ongotengera maphunziro a nyama. Zotsatira za zinthuzo zimatha kusiyana kwambiri pakati pa zamoyo, choncho, kusamala kumafunika potulutsa zotsatirazo kwa anthu. Kuphatikiza apo, kusowa kwa maphunziro athunthu anthawi yayitali kwalepheretsa kuwunika bwino kwa chitetezo chake.
7,8-Dihydroxyflavone (7,8-DHF) ndi flavonoid yochitika mwachilengedwe yomwe yalandira chidwi kwambiri pazabwino zake zathanzi, komabe, ndikofunikira kudziwa mlingo wovomerezeka ndi malangizowo mukamagwiritsa ntchito 7,8-DHF. zofunika.
Ndikofunika kukaonana ndi dokotala pankhani ya mlingo wa 7,8-DHF, chifukwa mlingo woyenerera ukhoza kusiyana malinga ndi zinthu zambiri monga msinkhu, kulemera kwake ndi matenda enaake. Kafukufuku wapano akuwonetsa zosankha zingapo za mlingo, nthawi zambiri 20 mpaka 60 mg patsiku. Komabe, ziyenera kuzindikirika kuti malingaliro awa sanakhazikitsidwe mwala ndipo akhoza kusintha pamene umboni wochuluka wa sayansi ukusonkhanitsidwa.
Pogula zakudya zowonjezera 7,8-DHF, ndikofunikira kusankha wopanga wodalirika komanso wodalirika kuti atsimikizire chitetezo ndi mphamvu ya mankhwalawa. Kuwerenga ndemanga zamakasitomala ndikuwunikanso mayeso a labotale a chipani chachitatu kungathandizenso kudziwa kudalirika kwa chinthu. Ndikofunikira kwambiri kutsatira malangizo a dokotala wanu. Azitha kukupatsani chitsogozo chaumwini malinga ndi mbiri yanu yachipatala komanso momwe thanzi lanu lilili. Nthawi zonse tikulimbikitsidwa kuti tiyambe ndi mlingo wotsika kwambiri ndipo pang'onopang'ono muwonjezere ngati pakufunika kuyang'aniridwa ndi katswiri wa zaumoyo.
Musanaphatikizepo 7,8-DHF muzakudya zanu zatsiku ndi tsiku, ndikofunikira kudziwa zovuta zilizonse zomwe zingachitike kapena kuyanjana ndi mankhwala. Ngakhale kuti 7,8-DHF nthawi zambiri imalekeredwa bwino, anthu ena angakumane ndi vuto la m'mimba pang'ono kapena kusamvana. Komanso, onetsetsani kuti mukudziwitsa dokotala wanu zamankhwala aliwonse kapena zowonjezera zomwe mukumwa kuti mupewe kuyanjana kulikonse. Kumbukirani kuti kutenga zowonjezera zilizonse kuyenera kukhala motsogozedwa ndi akatswiri azaumoyo kuti mukhale ndi thanzi labwino.
Q: Zimatenga nthawi yayitali bwanji kuti 7,8-dihydroxyflavoneor igwire ntchito?
A: Liwiro lomwe 7,8-dihydroxyflavone (7,8-DHF) imagwira ntchito imatha kusiyanasiyana kutengera zinthu zingapo. M'maphunziro asayansi, 7,8-DHF yawonetsa kuti ili ndi zotsatira zosiyanasiyana, monga kulimbikitsa kumasulidwa kwa neurotrophic factor ndi neuroprotection. Nthawi yomwe zimatengera kuti izi ziwonekere zimatha kukhala kuyambira maora mpaka masiku kapena kupitilira apo, kutengera momwe amachitira komanso chandamale cha gululo.
Chodzikanira: Nkhaniyi ndi yongofuna kudziwa zambiri ndipo siyenera kutengedwa ngati upangiri wachipatala. Nthawi zonse funsani akatswiri azachipatala musanagwiritse ntchito zowonjezera kapena kusintha dongosolo lanu lazaumoyo.
Nthawi yotumiza: Jul-04-2023
