NAD+ (Beta-Nicotinamide Adenine Dinucleotide) ndi coenzyme yomwe imapezeka m'maselo onse amoyo ndipo ndi yofunika kwambiri pa njira zosiyanasiyana zamoyo, kuphatikizapo kupanga mphamvu ndi kukonza DNA. Pamene tikukalamba, kuchuluka kwa NAD+ kumachepa, zomwe zimapangitsa kuti pakhale mavuto osiyanasiyana azaumoyo. Pofuna kuthana ndi vutoli, anthu ambiri amagwiritsa ntchito zowonjezera za NAD+ mu mawonekedwe a ufa. Komabe, ndi njira zambiri zomwe zilipo, kudziwa ufa wa NAD+ womwe ndi wabwino kwa inu kungakhale kovuta. Kusankha ufa wabwino kwambiri wa NAD+ kumafuna kuganizira mosamala za kuyera, kupezeka kwa bioavailability, mlingo, kumveka bwino, ndi mayankho a makasitomala. Mukayika patsogolo zinthu izi, mutha kupanga chisankho chodziwa bwino ndikusankha ufa wabwino kwambiri wa NAD+ womwe umathandizira thanzi lanu komanso thanzi lanu.
NAD imapezeka mwachilengedwe m'maselo athu,Komabe, makamaka mu cytoplasm yawo ndi mitochondria, milingo yachilengedwe ya NAD imachepa tikamakalamba (zaka 20 zilizonse, kwenikweni), zomwe zimayambitsa zotsatira zabwinobwino za ukalamba, monga kuchepa kwa mphamvu ndi kuwonjezeka kwa ululu ndi kupweteka. Kuphatikiza apo, kuchepa kwa NAD chifukwa cha ukalamba kumagwirizanitsidwa ndi matenda ena okhudzana ndi ukalamba, monga khansa, kuchepa kwa chidziwitso, ndi kufooka.
NAD+ si hormone, ndi coenzyme. NAD+ imatha kukonza mphamvu ya DNA yodzikonza yokha, kukulitsa moyo mwa kusintha kuchepa kwa mitochondria, ndikuteteza DNA ndi kuwonongeka kwa mitochondria. Ndipo imatha kukonza kukhazikika kwa ma chromosome. NAD+ imadziwikanso kuti "molekyulu yozizwitsa" yomwe imabwezeretsa ndikusunga thanzi la maselo. Mu kafukufuku wa nyama, zatsimikiziridwa kuti ili ndi mphamvu yayikulu yochiza matenda osiyanasiyana monga matenda a mtima, matenda a shuga, matenda a Alzheimer's, ndi kunenepa kwambiri.
NAD+ imagwira ntchito zosiyanasiyana m'maselo, monga glycolysis, mafuta acid oxidation, tricarboxylic acid cycle, respiratory chain, ndi zina zotero. Mu njira zimenezi, NAD+ imagwira ntchito ngati chotumizira hydrogen, kulandira ma elekitironi ndi hydrogen kuchokera ku ma substrates kenako nkuwasamutsa ku mamolekyu ena, monga NADH ndi FAD, kuti asunge redox bwino mkati mwa maselo. NAD+ imagwira ntchito yofunika kwambiri popanga mphamvu zamaselo, kuteteza ma free radicals, kukonza DNA, ndikupereka zizindikiro.
Kuphatikiza apo, NAD+ imagwirizananso kwambiri ndi ukalamba, ndipo kuchuluka kwake kumachepa ndi ukalamba. Chifukwa chake, kusunga kuchuluka kwa NAD+ kumachita gawo lofunikira pakuchedwetsa ukalamba, kuwonjezera mphamvu, kulimbikitsa kukonzanso kwa maselo, kukonza magwiridwe antchito a ubongo, komanso kuwongolera kagayidwe kachakudya.
Chochititsa chidwi n'chakuti, ukalamba umayendera limodzi ndi kuchepa pang'onopang'ono kwa milingo ya NAD+ m'maselo ndi minofu m'mitundu yosiyanasiyana ya zamoyo, kuphatikizapo makoswe ndi anthu.
Chifukwa chake, kudzaza thupi ndi NAD+ panthawi yake kungachedwetse ukalamba ndikutsimikizira thanzi. Ngati mukufuna kuti ukalamba ukhale nambala chabe, onjezerani NAD+ msanga momwe mungathere kuti muwoneke wachinyamata kuyambira mkati mpaka kunja.
Milingo ya NAD+ imachepa ndi ukalamba, makamaka chifukwa chakuti kuchuluka kwa kupanga kwake sikungafanane ndi kuchuluka kwa momwe amagwiritsira ntchito.
Kafukufuku wambiri wasonyeza kuti kuchepa kwa milingo ya NAD+ kumabwera chifukwa cha matenda ambiri okhudzana ndi ukalamba, kuphatikizapo kuchepa kwa chidziwitso, kutupa, khansa, matenda a kagayidwe kachakudya, sarcopenia, matenda a neurodegenerative, ndi zina zotero.
Ichi ndichifukwa chake tikufunika zowonjezera za NAD+. Monga momwe zilili ndi collagen yathu ya mtundu wachitatu, imatayika nthawi zonse.
NAD+ imatha kupirira ukalamba. Kodi mfundo yake ndi iti?
nad+ imayambitsa enzyme yokonzanso majini a parp1
Imathandiza kukonza DNA Chimodzi mwa zifukwa zomwe zimayambitsa ukalamba ndi kuwonongeka kwa DNA. Tsitsi lanu loyera, mazira ndi ziwalo zina zimachepa, zonse zimagwirizana ndi kuwonongeka kwa DNA. Kugona mochedwa komanso kukhala ndi nkhawa kumawonjezera kuwonongeka kwa DNA.
Kafukufuku wapeza kuti NAD+ imathandiza kuyambitsa jini ya PARP1 (yomwe imagwira ntchito ngati yankho loyamba kuti izindikire kuwonongeka kwa DNA kenako imalimbikitsa kusankha njira zokonzera. PARP1 imapangitsa kuti kapangidwe ka chromatin kachepe kudzera mu ADP ribosylation ya histones, ndipo imagwira ntchito pazinthu zosiyanasiyana zokonzanso DNA zomwe zimalumikizana ndikuzisintha, motero zimathandizira kukonza bwino), potero kukonza kuwonongeka kwa DNA ndikulimbikitsa kuyambitsa kusintha kwa kagayidwe kachakudya.
Mwachidule, NAD+ ingakhudze mwachindunji komanso mwanjira ina ntchito zofunika kwambiri zamaselo, kuphatikizapo njira zosinthira kagayidwe kachakudya, kukonza DNA, kukonzanso chromatin, ukalamba wamaselo, ntchito ya maselo oteteza chitetezo chamthupi, ndi zina zotero, motero kuchepetsa ukalamba wa anthu.
NAD+ Ndi chidule cha Chingerezi cha Nicotinamide adenine dinucleotide. Dzina lake lonse mu Chitchaina ndi nicotinamide adenine dinucleotide, kapena Coenzyme I mwachidule. Monga coenzyme yomwe imatumiza ma hydrogen ions, NAD+ imagwira ntchito m'mbali zambiri za kagayidwe ka thupi la munthu, kuphatikizapo glycolysis, Gluconeogenesis, tricarboxylic acid cycle, ndi zina zotero. Kafukufuku wina wasonyeza kuti kuchepa kwa NAD+ kumakhudzana ndi ukalamba, ndipo njira za thupi zomwe NAD+ imagwirira ntchito zimagwirizana ndi ukalamba, matenda a kagayidwe kachakudya, matenda a mitsempha ndi khansa, kuphatikizapo kuwongolera homeostasis ya maselo, ma sirtuin omwe amadziwika kuti "majini a moyo wautali", kukonza DNA, mapuloteni a banja la PARP okhudzana ndi necroptosis ndi CD38 yomwe imathandiza pakuwonetsa calcium.
Kuletsa Kukalamba
Ukalamba umatanthauza njira imene maselo amasiya kugawikana mosalekeza. Kuwonongeka kwa DNA kosakonzedwa kapena kupsinjika kwa maselo kungayambitse ukalamba. Ukalamba nthawi zambiri umatanthauzidwa ngati njira yowononga pang'onopang'ono ntchito za thupi ndi ukalamba; zizindikiro zakunja ndi kusintha kwa thupi komwe kumachitika chifukwa cha kutayika kwa minofu ndi mafupa, ndipo zizindikiro zamkati ndi kuchepa kwa kagayidwe kachakudya koyambira ndi ntchito ya chitetezo chamthupi.
Asayansi aphunzira za anthu okhala ndi moyo wautali, ndipo zotsatira za kafukufuku zikusonyeza kuti pali jini yokhudzana ndi moyo wautali mwa anthu okhala ndi moyo wautali - "jini la Sirtuins". Jini iyi idzatenga nawo mbali pakukonzanso mphamvu za thupi ndi kubwerezabwereza kwa DNA kuti isunge umphumphu ndi kukhazikika kwa jini, kuchotsa maselo okalamba, kukonza chitetezo cha mthupi kudzera mu zotsatira zotsutsana ndi kutupa ndi antioxidant, ndikuchedwetsa kukalamba kwa maselo abwinobwino.
Kuyambitsa kokhako kwa majini okhala ndi moyo wautali "Sirtuins" -NAD+
NAD+ ndi yofunika kwambiri kuti thupi likhale ndi thanzi labwino komanso loyenera. Kagayidwe kachakudya m'thupi, redox, kukonza ndi kukonza DNA, kukhazikika kwa majini, malamulo a epigenetic, ndi zina zotero zimafuna kuti NAD+ itenge nawo mbali.
NAD+ imasunga kulumikizana kwa mankhwala pakati pa nyukiliyasi ndi mitochondria, ndipo kufooka kwa kulumikizana ndi chifukwa chachikulu cha ukalamba wa maselo.
NAD+ imatha kuchotsa kuchuluka kwa ma code olakwika a DNA panthawi ya kagayidwe ka maselo, kusunga mawonekedwe abwinobwino a majini, kusunga magwiridwe antchito abwinobwino a maselo, ndikuchepetsa kukalamba kwa maselo a anthu.
Konzani kuwonongeka kwa DNA
NAD+ ndi gawo lofunikira la enzyme yokonza DNA ya PARP, yomwe imakhudza kwambiri kukonzanso DNA, kufotokozera majini, kukula kwa maselo, kupulumuka kwa maselo, kumanganso ma chromosome, ndi kukhazikika kwa majini.
Yambitsani puloteni yokhalitsa
Ma Sirtuin nthawi zambiri amatchedwa banja la mapuloteni okhala ndi moyo wautali ndipo amagwira ntchito yofunika kwambiri pakuwongolera ntchito za maselo, monga kutupa, kukula kwa maselo, kayendedwe ka circadian, kagayidwe ka mphamvu, ntchito ya mitsempha, komanso kukana kupsinjika, ndipo NAD+ ndi enzyme yofunika kwambiri popanga mapuloteni okhala ndi moyo wautali. Amayambitsa mapuloteni onse 7 okhala ndi moyo wautali m'thupi la munthu, akuchita gawo lofunika kwambiri pakukana kupsinjika kwa maselo, kagayidwe ka mphamvu, kupewa kusintha kwa maselo, apoptosis ndi ukalamba.
Perekani mphamvu
Zimathandizira kupanga mphamvu zoposa 95% zomwe zimafunika pa moyo. Mitochondria m'maselo a anthu ndi malo opangira mphamvu m'maselo. NAD+ ndi coenzyme yofunika kwambiri mu mitochondria yopanga molekyulu yamphamvu ya ATP, yomwe imasintha michere kukhala mphamvu yomwe thupi la munthu limafuna.
Kulimbikitsa kukonzanso kwa mitsempha yamagazi ndikusunga kusinthasintha kwa mitsempha yamagazi
Mitsempha yamagazi ndi minofu yofunika kwambiri pa moyo wathu. Pamene tikukalamba, mitsempha yamagazi imataya kusinthasintha kwake pang'onopang'ono ndipo imakhala yolimba, yokhuthala, komanso yopapatiza, zomwe zimayambitsa "arteriosclerosis." NAD+ imatha kuwonjezera ntchito ya elastin m'mitsempha yamagazi, motero kusunga kulimba kwa mitsempha yamagazi ndikusunga thanzi la mitsempha yamagazi.
Limbikitsani kagayidwe kachakudya
Kagayidwe kachakudya ndi kuchuluka kwa zochita zosiyanasiyana za mankhwala m'thupi. Thupi lidzapitiriza kusinthana zinthu ndi mphamvu. Kusinthana kumeneku kukatha, moyo wa thupi nawonso udzatha.
Pulofesa Anthony ndi gulu lake lofufuza ku Yunivesite ya California, USA, adapeza kuti NAD+ imatha kusintha bwino kuchepa kwa kagayidwe ka maselo komwe kumakhudzana ndi ukalamba, motero kukonza thanzi la anthu ndikuwonjezera moyo wawo.
Tetezani thanzi la mtima
Mtima ndi chiwalo chofunikira kwambiri mwa anthu, ndipo kuchuluka kwa NAD+ m'thupi kumachita gawo lofunika kwambiri pakusunga magwiridwe antchito a mtima. Kuchepa kwa NAD+ kungakhale kogwirizana ndi matenda ambiri a mtima, ndipo kafukufuku wambiri woyambira watsimikiziranso momwe kuwonjezera NAD+ kumakhudzira matenda a mtima.
Kuteteza matenda a mtima ndi mitsempha yamagazi
Kafukufuku wasonyeza kuti mitundu yonse isanu ndi iwiri ya sirtuins (SIRT1-SIRT7) imagwirizana ndi kufalikira kwa matenda a mtima. Sirtuins amaonedwa kuti ndi mankhwala ochizira matenda a mtima, makamaka SIRT1.
NAD+ ndiye chinthu chokhacho chomwe chimagwiritsidwa ntchito ndi Sirtuins. Kuonjezera NAD+ pa nthawi yake m'thupi la munthu kungathandize kuti ntchito ya mtundu uliwonse wa Sirtuins iyambe kugwira ntchito, motero kuteteza thanzi la mtima ndi kupewa matenda a mtima.
Limbikitsani kukula kwa tsitsi
Chifukwa chachikulu chomwe chimayambitsa kutayika kwa tsitsi ndi kutayika kwa mphamvu ya maselo a tsitsi, ndipo kutayika kwa mphamvu ya maselo a tsitsi ndi chifukwa chakuti kuchuluka kwa NAD+ m'thupi la munthu kumachepa. Maselo a tsitsi alibe ATP yokwanira yopangira mapuloteni a tsitsi, motero kutaya mphamvu zawo ndikupangitsa kuti tsitsi litayike. Chifukwa chake, kuwonjezera NAD+ kumatha kulimbitsa kayendedwe ka asidi ndikupanga ATP, kotero kuti maselo a tsitsi ali ndi mphamvu yokwanira yopangira mapuloteni a tsitsi, motero kutayika kwa tsitsi kumawonjezeka.
Chithandizo cha mamolekyulu a maselo a NAD+
Pamene ukalamba ukukwera, kuchuluka kwa NAD+ (Coenzyme I) m'thupi kumatsika pang'onopang'ono, zomwe zimapangitsa kuti thupi lizigwira ntchito komanso kukalamba kwa maselo! Pambuyo pa zaka zapakati, kuchuluka kwa NAD+ m'thupi la munthu kumachepa chaka ndi chaka. Pakatha zaka 50, kuchuluka kwa NAD+ m'thupi kumakhala theka lokha la kuchuluka kwa zaka 20. Pofika zaka 80, kuchuluka kwa NAD+ kumakhala pafupifupi 1% yokha ya zomwe anali nazo ali ndi zaka 20.
Ndiye, kodi ufa wa NAD+ umasiyana bwanji ndi zowonjezera zina zomwe zilipo pamsika? Tiyeni tiwone bwino mfundo zofunika kuziganizira:
1. Kupezeka kwa zinthu zachilengedwe:
Kusiyana kwakukulu pakati pa ufa wa NAD+ ndi zowonjezera zina ndikuti umapezeka mosavuta m'thupi. Ufa wa NAD+ umalowa mosavuta m'thupi ndipo umagwiritsa ntchito bwino ma coenzymes. Mosiyana ndi zimenezi, zowonjezera zina zimatha kukhala zochepa, zomwe zikutanthauza kuti thupi silingathe kuyamwa ndikugwiritsa ntchito bwino zosakanizazo.
2. Njira yogwirira ntchito:
Ufa wa NAD+ umagwira ntchito pobwezeretsa milingo ya NAD+ m'thupi, motero umathandizira ntchito zosiyanasiyana za maselo. Zowonjezera zina zimatha kukhala ndi njira zosiyanasiyana zogwirira ntchito, zomwe zimayang'ana njira kapena machitidwe enaake m'thupi. Kumvetsetsa njira zenizeni zogwirira ntchito za zowonjezera zosiyanasiyana kungakuthandizeni kudziwa zomwe zili zoyenera zosowa zanu.
3. Kafukufuku ndi umboni:
Poganizira zowonjezera zilizonse, ndikofunikira kuyang'ananso kafukufuku yemwe alipo komanso umboni womwe umatsimikizira kuti zimagwira ntchito bwino komanso kuti ndi zotetezeka. Ufa wa NAD+ wakhala ukuphunziridwa m'maphunziro ambiri, zomwe zikuwonetsa ubwino wake pa thanzi la maselo komanso moyo wautali. Kumbali ina, zowonjezera zina zitha kukhala ndi kafukufuku wochepa wotsimikizira zomwe akunena. Kumvetsetsa umboni wasayansi womwe uli kumbuyo kwa zowonjezera kungakuthandizeni kupanga zisankho zodziwa bwino za momwe zimagwiritsidwira ntchito.
4. Zosowa ndi zolinga za munthu payekha:
Pomaliza, chisankho chogwiritsa ntchito ufa wa NAD+ kapena zowonjezera zina chiyenera kutengera zosowa zanu komanso zolinga zanu zaumoyo. Ganizirani kufunsa katswiri wazachipatala kapena katswiri wazakudya wodziwa bwino ntchito kuti mudziwe zowonjezera zomwe zingakhale zothandiza kwambiri kwa inu. Zinthu monga zaka, moyo, ndi matenda omwe alipo zitha kukhala ndi gawo pakupanga njira yoyenera kwambiri yowonjezera.
Asayansi akhala akuiphunzira NAD+ kwa zaka 100. NAD+ si chinthu chatsopano chomwe chapezeka, koma chinthu chomwe chaphunziridwa kwa zaka zoposa 100.
NAD+ idapezeka koyamba mu 1904 ndi katswiri wa biochemist waku Britain Sir Arthur Harden, yemwe pambuyo pake adapambana Mphoto ya Nobel mu Chemistry mu 1929.
Mu 1920, Hans von Euler-Chelpin anapeza ndi kuyeretsa NAD+ koyamba ndipo anapeza kapangidwe kake ka dinucleotide, kenako anapambana Mphoto ya Nobel mu Chemistry mu 1929.
Mu 1930, Otto Warburg adapeza koyamba gawo lofunika la NAD+ ngati coenzyme mu kagayidwe ka zinthu ndi mphamvu, ndipo pambuyo pake adapambana Mphoto ya Nobel mu Zamankhwala mu 1931.
Mu 1980, George Birkmayer, pulofesa ku Dipatimenti ya Zamankhwala ku Yunivesite ya Graz ku Austria, anayamba kugwiritsa ntchito mankhwala ochepetsa NAD+ pochiza matenda.
Mu 2012, gulu lofufuza la Leonard Guarente, gulu lofufuza la katswiri wotchuka padziko lonse wa zamankhwala Stephen L. Helfand, ndi gulu lofufuza la Haim Y. Cohen motsatana adapeza kuti NAD+ imatha kutalikitsa ndodo za Caenorhabditis elegans. Nthawi ya moyo wa nematodes ndi pafupifupi 50%, imatha kutalikitsa moyo wa ntchentche za zipatso ndi pafupifupi 10%-20%, ndipo imatha kutalikitsa moyo wa mbewa zazimuna ndi zoposa 10%.
Kufufuza ndi kufufuza kwa asayansi pa moyo kwasinthidwa nthawi zonse komanso mobwerezabwereza. Mu Disembala 2013, David Sinclair, pulofesa wa majini ku Yunivesite ya Harvard, adasindikiza "Supplementing NAD with NAD" mu magazini yapamwamba kwambiri padziko lonse lapansi ya "Cell". "Pambuyo pa sabata imodzi yowonjezera NAD ndi mankhwala, nthawi ya moyo wa mbewa idakulitsidwa ndi 30%." Zotsatira za kafukufukuyu zidavumbulutsa koyamba kuti zowonjezera za NAD+ zimatha kusintha kwambiri ukalamba ndikuwonjezera nthawi ya moyo. Kafukufukuyu adadabwitsa dziko lonse lapansi ndipo adatsegula njira yodziwika bwino ya zowonjezera za NAD ngati zinthu zotsutsana ndi ukalamba. .
Ndi kupeza kodabwitsa kumeneku, NAD+ yakhazikitsa mgwirizano wosayerekezeka ndi mankhwala oletsa ukalamba. M'zaka zaposachedwapa, kafukufuku pa NAD+ wakula kwambiri m'magazini apamwamba kwambiri a SCI monga Science, Nature, ndi Cell, kukhala chinthu chodziwika bwino kwambiri m'gulu la zamankhwala. Akuti ichi ndi sitepe yakale yomwe anthu adatenga paulendo wolimbana ndi ukalamba ndikuwonjezera nthawi ya moyo.
1. Fufuzani mbiri ya kampaniyi komanso kuwonekera bwino kwake
Poganizira za mtundu winawake wa ufa wa NAD+, ndikofunikira kufufuza mbiri ya kampaniyo ndi kuwonekera bwino. Yang'anani mitundu yomwe imaika patsogolo kuwonekera bwino mu njira zawo zopezera ndi kupanga. Mitundu yodziwika bwino idzapereka zambiri mwatsatanetsatane za momwe amapezera ufa wa NAD+, kuphatikizapo mtundu wa zipangizo zopangira ndi miyezo yopangira yomwe amatsatira. Kuphatikiza apo, yang'anani ndemanga za makasitomala ndi maumboni kuti muwone kukhutitsidwa konse kwa ogwiritsa ntchito ena ndi zomwe akumana nazo ndi zinthu za mtunduwo.
2. Unikani kuyera kwa ufa wa NAD+
Chiyero ndi chinthu chofunikira kwambiri posankha mtundu wa ufa wa NAD+. Ufa wa NAD+ wabwino kwambiri uyenera kukhala wopanda zodetsa ndi zodzaza, kuonetsetsa kuti mukupeza chinthu choyera komanso chogwira mtima. Yang'anani mitundu yomwe imachita mayeso a chipani chachitatu kuti itsimikizire kuyera kwa ufa wawo wa NAD+. Kuyesa kwa chipani chachitatu kumapereka chitsimikizo chowonjezera kuti zinthuzo zikukwaniritsa miyezo yapamwamba kwambiri ya kuyera ndipo zilibe zinthu zovulaza.
3. Ganizirani njira zopangira zinthu ndi miyezo yaubwino
Njira yopangira imagwira ntchito yofunika kwambiri pa ubwino wa ufa wa NAD+. Sankhani mitundu yomwe imatsatira njira zowongolera khalidwe ndikutsatira Njira Zabwino Zopangira (GMP). Chitsimikizo cha GMP chimatsimikizira kuti zinthu zimapangidwa pamalo oyera komanso olamulidwa, kuchepetsa chiopsezo cha kuipitsidwa ndikuwonetsetsa kuti zinthuzo ndi zabwino nthawi zonse. Kuphatikiza apo, funsani za kudzipereka kwa mtunduwo pakusunga zinthu mokhazikika komanso machitidwe abwino opezera zinthu, chifukwa zinthuzi zingasonyezenso ubwino wonse wa chinthucho.
4. Unikani kuchuluka kwa bioavailability ndi kuyamwa kwa ufa wa NAD+
Kupezeka kwa zinthu m'thupi kumatanthauza kuthekera kwa thupi kuyamwa ndikugwiritsa ntchito zosakaniza zomwe zili mu chowonjezera. Mukasankha mtundu wa ufa wa NAD+, ganizirani kupezeka kwa zinthu m'thupi. Yang'anani mitundu yomwe imagwiritsa ntchito njira zamakono zoperekera kapena ukadaulo kuti iwonjezere kupezeka kwa zinthu m'thupi la NAD+. Izi zitha kuphatikizapo zinthu monga micronization kapena encapsulation, zomwe zingathandize kuyamwa kwa NAD+ m'thupi, pamapeto pake kukulitsa kugwira ntchito kwake.
5. Fufuzani kafukufuku wa sayansi ndi kafukufuku wazachipatala
Mitundu yodziwika bwino ya ufa wa NAD+ nthawi zambiri imapereka maphunziro asayansi ndi azachipatala kuti athandizire kugwira ntchito bwino komanso chitetezo cha zinthu zawo. Yang'anani mitundu yomwe imayika ndalama mu kafukufuku ndi chitukuko, chifukwa izi zikusonyeza kudzipereka popanga zinthu zapamwamba komanso zozikidwa pa umboni. Kutsimikizika kwa sayansi kumatsimikizira kuti ufa wa NAD+ wayesedwa kwambiri ndikuwunikidwa, zomwe zikutsimikiziranso kuti ndi wabwino komanso woyera.
Suzhou Myland Pharm & Nutrition Inc. yakhala ikugwira ntchito mu bizinesi yowonjezera zakudya kuyambira mu 1992. Ndi kampani yoyamba ku China kupanga ndikugulitsa zotulutsa za mbewu za mphesa.
Kampaniyi, yomwe ili ndi zaka 30 zokumana nazo komanso yoyendetsedwa ndi ukadaulo wapamwamba komanso njira yabwino kwambiri yofufuzira ndi chitukuko, yapanga zinthu zosiyanasiyana zopikisana ndipo yakhala kampani yatsopano yopereka chithandizo cha sayansi ya moyo, kupanga zinthu mwamakonda komanso kupanga zinthu.
Kuphatikiza apo, Suzhou Myland Pharm & Nutrition Inc. ndi kampani yodziwika bwino yopanga mankhwala yomwe ili ndi dzina la FDA. Zipangizo za kafukufuku ndi chitukuko cha kampaniyi, malo opangira mankhwala, ndi zida zowunikira ndi zamakono komanso zogwira ntchito zambiri ndipo zimatha kupanga mankhwala kuyambira mamiligalamu mpaka matani ambiri, komanso zimagwirizana ndi miyezo ya ISO 9001 ndi zomwe zimapangidwa ndi GMP.
Q: Kodi zowonjezera za NAD+ zimagwiritsidwa ntchito pa chiyani?
A: Chowonjezera cha NAD+ ndi chowonjezera cha zakudya chomwe chimawonjezera coenzyme NAD+ (nicotinamide adenine dinucleotide). NAD+ imagwira ntchito yofunika kwambiri pa kagayidwe ka mphamvu ndi kukonzanso maselo mkati mwa maselo.
Q: Kodi zowonjezera za NAD+ zimagwiradi ntchito?
A: Kafukufuku wina akusonyeza kuti zowonjezera za NAD+ zingathandize kukonza kagayidwe ka mphamvu m'maselo ndikuchepetsa ukalamba.
Q: Kodi zakudya za NAD+ zimachokera kuti?
A: Zakudya zomwe zili ndi NAD+ zimaphatikizapo nyama, nsomba, mkaka, nyemba, mtedza ndi ndiwo zamasamba. Zakudya zimenezi zili ndi niacinamide ndi niacin yambiri, yomwe ingasinthidwe kukhala NAD+ m'thupi.
Q: Kodi ndingasankhe bwanji chowonjezera cha NAD+?
A: Mukasankha zowonjezera za NAD+, ndi bwino kuyamba mwafunsa upangiri kwa dokotala kapena katswiri wa zakudya kuti mumvetse zosowa zanu za zakudya komanso thanzi lanu. Kuphatikiza apo, sankhani mtundu wodziwika bwino, yang'anani zosakaniza za mankhwalawa ndi mlingo wake, ndikutsatira malangizo a mlingo womwe uli patsamba lowonjezera la mankhwalawa.
Chodzikanira: Nkhaniyi ndi yongofuna kudziwa zambiri ndipo siyenera kuonedwa ngati upangiri uliwonse wa zachipatala. Zina mwa zomwe zili mu blog iyi zimachokera pa intaneti ndipo si zaukadaulo. Webusaitiyi ili ndi udindo wosankha, kupanga ndi kusintha nkhani zokha. Cholinga chopereka zambiri sichikutanthauza kuti mukugwirizana ndi malingaliro ake kapena kutsimikizira kuti zomwe zili mkati mwake ndi zoona. Nthawi zonse funsani katswiri wa zaumoyo musanagwiritse ntchito zowonjezera zilizonse kapena kusintha njira yanu yazaumoyo.
Nthawi yotumizira: Ogasiti-05-2024
