Dzina la sayansi la NAD ndi nicotinamide adenine dinucleotide. NAD + ilipo mu selo lililonse la thupi lathu. Ndi metabolite yofunika kwambiri komanso coenzyme munjira zosiyanasiyana za metabolic. Imayimira pakati ndikuchita nawo njira zosiyanasiyana zamoyo. Ma enzymes opitilira 300 amadalira NAD + Kuti agwire ntchito. Komabe, zomwe zili mu NAD + sizokhazikika. Tikamakalamba, zomwe zili mu NAD + m'maselo zimachepa. Makamaka pambuyo pa zaka 30, mlingo wa NAD + udzatsika kwambiri, zomwe zimabweretsa kuchepa kwa ntchito zambiri motero kusonyeza zizindikiro za ukalamba. Nicotinamide riboside chloride ndi mtundu wa vitamini B3. Nicotinamide riboside chloride imatha kusinthidwa kukhala NAD+ (nicotinamide adenine dinucleotide). Ndi amodzi mwa otsogola kwambiri a NAD +. Imatengedwa mosavuta ndi thupi ndikugwiritsa ntchito. Kafukufuku wambiri wawonetsa kuti kuthandizira kwa NRC kumatha kukulitsa milingo ya NAD +, yomwe imatha kubweretsa phindu pama metabolic, mtima ndi mitsempha yamanjenje. Nthawi zambiri amagwiritsidwa ntchito ngati chakudya chothandizira kulimbikitsa thanzi labwino komanso thanzi.
Nicotinamide riboside chloride (NRC) ndi yochokera ku vitamini B3 ndi chinthu chatsopano cha bioactive. Amapangidwa ndi ribose molekyulu ya shuga ndi chigawo cha vitamini B3 nicotinamide (yomwe imadziwikanso kuti nicotinic acid kapena vitamini B3). Atha kudyedwa kudzera mukudya nyama, nsomba, chimanga ndi zakudya zina kapena kudzera muzowonjezera za NRC.
Nicotinamide ribose chloride imatha kusinthidwa kukhala NAD+ (nicotinamide adenine dinucleotide) ndikuchita zamoyo mkati mwa ma cell. NAD + ndi coenzyme yofunikira ya intracellular yomwe imagwira nawo ntchito zosiyanasiyana zamagetsi zamagetsi, kuphatikiza kupanga mphamvu, kukonza DNA, kuchuluka kwa ma cell, ndi zina zambiri. Panthawi ya ukalamba wa thupi la munthu, zomwe zili mu NAD + zimachepa pang'onopang'ono. Nicotinamide riboside chloride supplementation imatha kukulitsa mulingo wa NAD +, womwe ukuyembekezeka kuchedwetsa kukalamba kwa maselo ndi matenda okhudzana nawo.
Kafukufuku wa nicotinamide riboside chloride wawonetsa kuti ili ndi zinthu zambiri zamoyo, monga:
Kupititsa patsogolo kagayidwe kazakudya, kuwonjezera kupirira ndi kuchita masewera olimbitsa thupi;
Kupititsa patsogolo ntchito zamanjenje ndi kukumbukira;
Kupititsa patsogolo chitetezo cha mthupi.
Ponseponse, nicotinamide riboside chloride ndiwopatsa chiyembekezo kwambiri pazakudya zokhala ndi chiyembekezo chogwiritsa ntchito kwambiri.
Kuphatikiza apo, nicotinamide ribose chloride imagwiritsidwanso ntchito kwambiri pofufuza zasayansi. Monga kalambulabwalo wa NAD+, chitha kugwiritsidwa ntchito powerenga biosynthesis ndi njira za metabolic za NAD+ ndi zina zokhudzana nazo. Nthawi yomweyo, nicotinamide riboside chloride imagwiritsidwanso ntchito ngati chopangira pazaumoyo komanso zodzoladzola kulimbikitsa thanzi la ma cell ndikuchepetsa kukalamba kwa khungu.
Ukalamba ndi mutu wamuyaya kwa anthu. Malinga ndi kafukufuku wa asayansi, kukalamba kwa maselo kumagwirizana kwambiri ndi kuchepa kwa nicotinamide adenine dinucleotide (NAD). NAD ndi gawo lofunikira pa metabolism ndi kukonza ma cell m'thupi la munthu. Sizingangochedwetsa ukalamba, komanso kukhalabe ndi mphamvu zama cell komanso kukhala ndi thanzi labwino komanso lamalingaliro. koma. Tikamakalamba, milingo ya NAD m'matupi athu imatsika mwachangu komanso mwachangu, ndipo imatha kutsika ndi theka lazaka zapakati pa 40 ndi 80.
Pali enzyme yofunika kwambiri m'thupi lathu, yomwe ndi gawo lalikulu la metabolism yamphamvu yama cell. Ndilofunika bwanji? Pafupifupi njira zonse zomwe zimapangitsa kuti thupi lizigwira ntchito bwino, monga kagayidwe, kukonza, komanso chitetezo chamthupi, zimafunikira kutenga nawo gawo kwa enzyme iyi. Pamene miyeso ya enzymeyi ikuchepa, zizindikiro zambiri ndi matenda okhudzana ndi ukalamba amatha kuchitika, monga matenda a kagayidwe kachakudya, kufooka kwa chitetezo cha mthupi, kuchepa kwa chidziwitso, etc. Enzyme yofunikayi ili ndi dzina lalitali: nicotinamide adenine dinucleotide, kapena NAD +.
Mwachidule, kuchepa kwa NAD + m'thupi kumatanthauza kukalamba. Ndiye, titha kuwonjezera NAD + m'thupi kuti tichedwetse kukalamba? Mukawonjezera mwachindunji NAD +, thupi la munthu silingathe kuyamwa, ndipo lidzakhala ndi zotsatira zoyipa. Chifukwa chake, anthu adatembenukira kuzinthu zoyambira za NAD +: nicotinamide ribose chloride (NRC).
Nicotinamide riboside chloride ndi mtundu wa vitamini B3 komanso imodzi mwazinthu zophunzirira kwambiri za NAD +. Imatengedwa mosavuta ndikugwiritsidwa ntchito ndi thupi. Kafukufuku wambiri wawonetsa kuti kuwonjezera pa NR kumatha kukulitsa milingo ya NAD +, yomwe imatha kubweretsa phindu pama metabolic, mtima ndi mitsempha yamanjenje.
Mawu akuti "anti-aging" amapeza rap yoyipa. Zikumveka ngati tikuyesera kuletsa chinthu chomwe chayamba kale, kapena sitingathe kukumbatira mbali zathu zomwe tiyenera kuzikonda. Koma zoona zake n’zakuti kusintha kwa kagayidwe kachakudya kumachitika pansi pa khungu tisanaone zotsatira za ukalamba. Kusankha kutengera thanzi lathu kuchokera mkati kungakhale kofunika kwambiri kuti tiwongolere momwe timakalamba.
M'malo mwake, chimodzi mwazizindikiro za ukalamba ndi njira yomwe imadziwika kuti "mitochondrial dysfunction," mawu omwe amatanthauza kutayika kwathunthu kwa mphamvu ndi mphamvu zama cell athu pakapita nthawi. Ichi chikhoza kukhala chimodzi mwa zifukwa zomwe timakalamba. Ngati mitochondria ili pamtima pa ukalamba wathu, ndikofunika kufufuza njira iliyonse yotheka kuti igwire ntchito kwa nthawi yayitali.
Phunzirani za mitochondria.
Pafupifupi m’kati mwa selo lililonse muli tinthu tating’ono ting’ono, tooneka modabwitsa totchedwa mitochondria—“mphamvu ya selo.” Ziwalo ting'onoting'onozi ndizomwe zimapanga 90% ya mphamvu zomwe matupi athu amafuna. Mitochondria ndi chifukwa chake tilipo lero monga nyama zovuta osati mabakiteriya.
Sitidziwa nthawi zonse kuti mitochondria ndi yofunika bwanji pa thanzi lathu. Njira yofunika kwambiri yosungira mitochondria yanu yathanzi ndi molekyulu yotchedwa NAD+ (nicotinamide adenine dinucleotide). Maselo athu mwachilengedwe amapanga NAD + ndipo timaigwiritsa ntchito mosalekeza tsiku lonse.
Tikudziwanso kuti kupezeka kwathu kwa NAD + kumachepa tikamakalamba. Ofufuza atazindikira kuti NAD + ikhoza kukhala ndi kiyi kuti ma cell athu azikhala athanzi, adangoyang'ana kuti apeze njira yoti apindule nawo.
Ofufuza akudziwa kale kuti mavitamini awiri amayamba kupanga mankhwala owonjezera NAD +: niacin ndi niacinamide. Izi zinapezeka m'ma 1930 pofuna kuchiza pellagra, kusowa kwa vitamini B3 komwe kungakhale koopsa.
Niacin adakhalanso mankhwala a cholesterol yayikulu m'ma 1950s. Komabe, zapezeka kuti kumwa Mlingo wambiri wa niacin nthawi zina kungayambitse kutulutsa kwapakhungu komwe kumakwiyitsa komanso kosawoneka bwino.
Niacinamide sichimayambitsa kutulutsa khungu ndipo ingathe kupereka zabwino zambiri zomwezo, koma imalepheretsa kuyambitsa kwa mapuloteni ofunikira okonzanso ma cell otchedwa sirtuins. Niacinamide kapena niacin sizinali zogwira mtima monga momwe ofufuza ankayembekezera.
Ngakhale mavitamini awiriwa ndi otsogola a NAD +, si yankho labwino. Chifukwa cha zotsatira zoyipa za niacin komanso mphamvu ya nicotinamide, ofufuza alibebe mavitamini okwanira kuti achulukitse milingo ya NAD+.
Kupezeka kwa nicotinamide riboside.
Mtundu wina wa vitamini B3 wotchedwa nicotinamide riboside unapezeka mu yisiti mu 1940s. Koma sizinali mpaka kumayambiriro kwa zaka za m'ma 2000 pamene asayansi anayamba kuona kuthekera kwa vitamini B3 yachitatu, osati kuwonjezera NAD + komanso kupititsa patsogolo thanzi laumunthu. Mu 2004, gulu lofufuza la Dartmouth College linapeza kuti nicotinamide riboside, monga mchimwene wake wa vitamini B3, ndi kalambulabwalo wa NAD+.
Gulu lofufuza motsogozedwa ndi Dr. Charles Brenner linapeza kuti nicotinamide riboside inachulukitsa NAD + mu mbewa, ndipo mbewa zinapeza ubwino wambiri wathanzi chifukwa cha izi.
Makoswe adawonetsa chilichonse kuyambira pakuwongolera shuga m'magazi ndi kuchuluka kwa cholesterol mpaka kuwonongeka kwa mitsempha komanso kukana kulemera. Dr. Charles Brenner adapeza zotsatirazi kukhala zolimbikitsa kwambiri kotero kuti anatenga sitepe yotsatira kuti amvetse tanthauzo la nicotinamide riboside pa thanzi laumunthu.
Mu 2014, Dr. Brenner anakhala munthu woyamba kutenga nicotinamide riboside monga chowonjezera. Zotsatira zake n’zolimbikitsanso. Mtundu wosadziwika wa vitamini B3 udakulitsa kwambiri milingo yake ya NAD+ mosatekeseka, mwachangu, komanso popanda zovuta zilizonse.
Nicotinamide riboside imagwiritsa ntchito njira yapadera yopangira NAD + yomwe palibe vitamini B3 wina amagwiritsa ntchito.
Nicotinamide riboside imathanso kuyambitsa ma sirtuin omwe amalimbikitsa kukonza ma cell. Pamene tikukalamba, ma sirtuinwa amagwira ntchito mowonjezereka kuti athandize maselo kukhala olimba.
Kukhala wathanzi muzaka zakubadwa sikukhala kophweka ngati vitamini imodzi, ngakhale yodalirika ngati nicotinamide riboside. Pali maphunziro opitilira 100 omwe amafufuza nicotinamide riboside, ambiri omwe akuwonetsa kuti kuchuluka kwa NAD + kumalumikizidwa ndi thanzi la metabolic ndi minofu mu mbewa. Kafukufuku wowonjezera akupitirirabe kuti amvetsetse udindo wa NAD + pothandizira zovuta zina zokhudzana ndi ukalamba, kuphatikizapo kuchepa kwa chiwindi, kunenepa kwambiri, kuchuluka kwa insulini ndi ntchito ya ubongo mu mbewa.
NAD ndi chiyani?
NAD+ ndi coenzyme I, yomwe ndi coenzyme yomwe imasamutsa ma protons (molondola, ma hydrogen ion) ndikuchita nawo zinthu zambiri zakuthupi monga ma cell metabolism, kaphatikizidwe kamphamvu, ndi kukonza ma DNA. NAD + ndi michere yofunika kuti igwire ntchito ya protein ya Sirtuin, yomwe imatchedwa "longevity factor" ndi asayansi. Makamaka, imatha kusunga kutalika kwa ma telomere ofunikira, kuchepetsa ukalamba ndikuwonjezera moyo.
NAD + imathanso kulimbikitsa kukonza ma jini ndikuchedwetsa kukalamba kwa maselo. NAD + imalimbikitsa kusinthika kwa ma cell ndikukana matenda a chitetezo chamthupi. NAD + imathandizira kukhazikika kwa chromosome ndikuchepetsa chiopsezo cha khansa.
Ndi abwenzi apamtima a ma enzymes, omwe amathandiza kupatsa mafuta "makina am'manja" omwe amapanga mphamvu zofunikira pakuchita chilichonse chachikulu m'thupi lanu pama cell.
Chifukwa chiyani NAD + ndiyofunikira?
Chifukwa cha gawo lofunikira pakupanga mphamvu zama cell, kusowa kwa NAD + m'thupi lanu kumapangitsa kuti ntchito zambiri zam'thupi zikhale zopanda ntchito. Popanda NAD, mapapo anu sangathe kutulutsa mpweya, mtima wanu sudzatha kupopa magazi, ndipo ubongo wanu sungathe kuyaka.
NAD+ imathandizanso kulimbikitsa kukonza kwa DNA ndikuwongolera magwiridwe antchito a cell pogwira ntchito ndi ma sirtuins ndi poly(ADP-ribose) polymerases (PARPs), omwe ndi ofunikira pakuwongolera mayankho amtundu wa chipongwe monga kudya mopambanitsa, kumwa mowa, kusokoneza kugona, komanso kungokhala. Ma enzyme.
NAD + ndi kukalamba
Kafukufuku wopangidwa mu 2012 ndi gulu lochokera ku Dipatimenti ya Pharmacology ku yunivesite ya New South Wales adawonetsa kuti NAD metabolism imagwirizana ndi zaka. Kafukufukuyu akuwonetsa kuti milingo ya NAD + pakhungu la munthu imatsika mpaka 50% pakati pa zaka za 40 ndi 60, ndikuti kuchepa kwa NAD + kumatha kukhala ndi gawo lofunikira pakukalamba.
"Kugwirizana kwakukulu koyipa kudawonedwa pakati pa milingo ya NAD + ndi zaka mwa amuna ndi akazi," ofufuzawo adatero mu pepalalo.
Kuphatikiza apo, NAD imakhudzidwa ndi kupuma kwa ma cell, makamaka mu mitochondria, ndipo imathandizira ku thanzi la mitochondrial. Pali chidwi champhamvu cha sayansi pakukhudzidwa kwa NAD mu vuto la mitochondrial, chimodzi mwazizindikiro za ukalamba.
M'zaka zaposachedwa, kafukufuku wayang'ana kwambiri kumvetsetsa gawo la NAD pothana ndi kuchepa kwa magwiridwe antchito okhudzana ndi zaka.
Nicotinamide Ribose Chloride imawonjezera milingo ya NAD +.
NR ndi kalambulabwalo wa NAD, zomwe zikutanthauza kuti ndi "chimangira" chomwe mamolekyu a NAD + amapangidwa. Idapezeka mu 2004 ngati kalambulabwalo wa vitamini ku NAD +, ndikupangitsa kuti ikhale imodzi mwazochita zaposachedwa kwambiri mu kafukufuku wa NAD +.
NR ndi vitamini yochitika mwachilengedwe komanso mtundu watsopano wa vitamini B3, koma kugwiritsidwa ntchito kwake ngati chowonjezera kumakhudzidwa kwambiri ndi "mavitamini okalamba". Ndiwothandiza kwambiri pakukulitsa NAD, ndikupangitsa kuti ikhale imodzi mwamachitidwe osangalatsa kwambiri pakutha kwa ukalamba wathanzi.
NR imatha kukulitsa milingo ya NAD +. Mayesero azachipatala omwe adasindikizidwa mu Scientific Reports adawonetsa kuti adachulukitsa NAD + mpaka 50% patatha milungu iwiri atamwa.
Ngakhale kuti NR supplementation yatsimikiziridwa mwachipatala kuti ikuwonjezera milingo ya NAD +, NAD + supplementation ngati choyimira choyimirira sizothandiza.
NAD+ ndi molekyulu yayikulu kwambiri ndipo siyingalowe m'maselo mwachindunji. M’malo mwake, thupi lanu liyenera kuliphwanya m’tizidutswa ting’onoting’ono lisanadutse nembanemba ya selo. Zigawozi zimalumikizidwanso mkati mwa batire.
Nicotinamide riboside (NR) ndi nicotinamide riboside chloride (NRC) ndi mitundu yonse ya vitamini B3, yomwe imatchedwanso niacin. Vitamini B3 ndi mchere wofunikira womwe umagwira ntchito zosiyanasiyana za thupi, kuphatikizapo kupanga mphamvu, kukonza DNA, ndi kagayidwe ka maselo. Onse a NR ndi NRC ndi otsogola a nicotinamide adenine dinucleotide (NAD +), coenzyme yomwe imagwira ntchito zosiyanasiyana zamoyo, monga kuwongolera kupanga mphamvu zama cell ndikuthandizira kukonza DNA.
Nicotinamide riboside (NR) ndi mtundu wa vitamini B3 womwe watenga chidwi ndi zomwe zimatha kuletsa kukalamba komanso kulimbikitsa mphamvu. Ndi mankhwala omwe amapezeka mwachilengedwe omwe amapezeka muzakudya zina, koma amapezekanso ngati chakudya chowonjezera. NR imadziwika kuti imatha kukulitsa milingo ya NAD + m'thupi, yomwe imatha kuthandizira ntchito ya mitochondrial, kukulitsa kupanga mphamvu zama cell, komanso kupereka chitetezo ku kuchepa kwa zaka.
Komano, Nicotinamide riboside chloride (NRC), ndi mtundu wa mchere wa NR ndipo umagwiritsidwa ntchito kwambiri muzakudya zowonjezera. Kuonjezera chloride ku NR kumapanga NRC, yomwe imakhulupirira kuti imathandizira kukhazikika kwapawiri ndi bioavailability. Izi zikutanthauza kuti NRC ikhoza kukhala ndi kuyamwa ndi kugwiritsidwa ntchito bwino m'thupi kuposa NR yokha ndipo ikhoza kukhala ndi zotsatira zodziwika bwino pamagulu a NAD + ndi ntchito zama cell.
Chimodzi mwa kusiyana kwakukulu pakati pa NR ndi NRC ndi kapangidwe kake ka mankhwala. NR ndiye maziko a pawiriwa, pomwe NRC ndi mtundu wosinthidwa wokhala ndi chloride wowonjezera. Kusintha kumeneku kumapangitsa kusungunuka kwapawiri ndi bioavailability, kupangitsa kuti thupi lizitha kuyamwa ndikugwiritsa ntchito mosavuta.
Ponena za ubwino wawo wathanzi, NR ndi NRC zimaganiziridwa kuti zimakhala ndi zotsatira zofanana chifukwa cha mphamvu zawo zowonjezeraNAD +milingo. Zotsatirazi zingaphatikizepo kupititsa patsogolo ntchito ya mitochondrial, kupititsa patsogolo mphamvu za metabolism, komanso kuthandizira thanzi labwino la ma cell. Komabe, kugwiritsa ntchito NRC muzowonjezera kumatha kubweretsa mwayi wowonjezera wamayamwidwe ndi kugwiritsa ntchito bwino, zomwe zitha kubweretsa phindu lodziwika bwino poyerekeza ndi kugwiritsa ntchito NR yokha.
1. Limbikitsani kupanga mphamvu zama cell
Chimodzi mwazinthu zodziwika bwino zanicotinamide riboside kloride ndi gawo lake pakulimbikitsa kupanga mphamvu zama cell. NR ndiye kalambulabwalo wa nicotinamide adenine dinucleotide (NAD+), coenzyme yomwe imathandizira kupanga adenosine triphosphate (ATP), ndalama yayikulu yama cell. udindo wofunikira. Tikamakalamba, milingo ya NAD + imachepa, zomwe zimapangitsa kuchepa kwa mphamvu zama cell. Powonjezera ndi NR, akukhulupirira kuti milingo ya NAD + imatha kubwezeredwa, potero imathandizira kagayidwe kabwino ka ma cell.
2. Ntchito ya Mitochondrial ndi moyo wautali
Mitochondria ndi malo opangira mphamvu zama cell, omwe ali ndi udindo wopanga mphamvu ndikuwongolera ma cell. Kafukufuku akuwonetsa kuti Nicotinamide Riboside Chloride imatha kuthandizira ntchito ya mitochondrial polimbikitsa biogenesis ya mitochondria yatsopano ndikuwonjezera mphamvu zawo. Izi zimakhudzanso moyo wonse komanso ukalamba wathanzi, chifukwa mitochondria yogwira ntchito bwino ndiyofunikira kwambiri kuti ma cell akhale ndi thanzi labwino komanso olimba.
3. Kuwongolera thanzi la metabolic ndi kulemera
NAD + ndi coenzyme, kapena molekyulu yowonjezera, yomwe imakhudzidwa ndi zochitika zambiri zamoyo. Kafukufuku waposachedwa adapeza kuti nicotinamide ribose supplementation imatha kulimbikitsa kagayidwe ka NAD + mwa achikulire athanzi komanso okalamba. Osati kokha zowonjezera za NR zomwe zinaloledwa bwino ndi otenga nawo mbali, zikhoza kuthandizira kuchepetsa kuthamanga kwa magazi ndi kuuma kwa mitsempha. Kuperewera kwa NAD + ndizomwe zimayambitsa ukalamba komanso matenda ambiri, ndipo kafukufuku akuwonetsa kuti kubwezeretsa milingo ya NAD + kuli ndi chithandizo chamankhwala komanso thanzi.
Powonjezera milingo ya NAD +, nicotinamide ribose imapindulitsa kuwongolera kagayidwe kachakudya, nkhokwe zamphamvu, kaphatikizidwe ka DNA, ndi ntchito zina zathupi.
Kuphatikiza apo, kafukufuku wasonyeza kuti kuphatikizika kwa NR kumatha kukulitsa chidwi cha insulin, kuchepetsa kutupa, komanso kukulitsa kusinthasintha kwa metabolic. Izi zitha kukhala zopindulitsa makamaka kwa anthu omwe akufuna kuwongolera kulemera kwawo ndikuthandizira thanzi la metabolic.
4. Kugwira ntchito kwachidziwitso ndi thanzi laubongo
Monga kalambulabwalo wa NAD +, nicotinamide ribose imateteza maselo aubongo ku kupsinjika kwa okosijeni, komwe kungayambitse matenda aubongo okhudzana ndi ukalamba. M'kati mwa maselo a ubongo, NAD + imathandizira kupanga PGC-1-alpha, mapuloteni omwe amawoneka kuti amathandiza kuteteza maselo kupsinjika kwa okosijeni ndi kuwonongeka kwa mitochondrial.
Ofufuza adapeza kuti mu mbewa, kuchepa kwa NAD + kumatenga gawo lalikulu mu neuroinflammation, kuwonongeka kwa DNA, komanso kuwonongeka kwa neuronal mu matenda a Alzheimer's. Komanso mu kafukufuku wa test tube, nicotinamide riboside idakulitsa milingo ya NAD+ ndikuwongolera kwambiri ntchito ya mitochondrial m'maselo amtundu wa odwala matenda a Parkinson.
Kafukufuku wotulukapo akulozeranso za phindu la chidziwitso cha nicotinamide riboside chloride. NAD + imakhudzidwa ndi njira zosiyanasiyana zokhudzana ndi thanzi laubongo, kuphatikiza ma neuronal signing, kukonza DNA, ndikuchotsa mapuloteni owonongeka. Pothandizira milingo ya NAD +, NR ikhoza kuthandizira kusunga chidziwitso ndikuletsa kuchepa kwa chidziwitso chokhudzana ndi ukalamba.
5. Maseŵera Othamanga ndi Kubwezeretsa
Kafukufuku wa 2019 wofalitsidwa mu European Journal of Nutrient Impurities adapeza kuti kugwiritsa ntchito nicotinamide ribose zowonjezera kumathandizira luso lakuthupi ndikuchepetsa kupsinjika kwa okosijeni mwa okalamba.
Ofufuzawo adawona kuti kuphatikizika kwa NR kunali kopindulitsa kwa anthu osowa NAD +, kufotokoza chifukwa chake kunali kothandiza kwambiri kwa akulu akulu kuposa achichepere.
Othamanga ndi okonda masewera olimbitsa thupi angakhale ndi chidwi chodziwa kuti nicotinamide riboside chloride imatha kukhudza bwino masewera othamanga komanso kuchira. NAD + imagwira ntchito yofunika kwambiri pakuwongolera njira zama cell zomwe zimakhudzidwa ndi kupanga mphamvu komanso kugwira ntchito kwa minofu. Pothandizira magawo a NAD +, NR imatha kupititsa patsogolo kupirira, kuwongolera kuchira kwa minofu, komanso kupititsa patsogolo masewera olimbitsa thupi.
Ubwino ndi Ungwiro
Mukagula nicotinamide riboside chloride powder, khalidwe ndi chiyero ziyenera kukhala patsogolo panu. Yang'anani zinthu zopangidwa ndi makampani odziwika bwino komanso gulu lachitatu loyesedwa kuti likhale loyera komanso lamphamvu. Moyenera, zogulitsa ziyenera kukhala zopanda zoipitsa ndi zodzaza kuti muwonetsetse kuti mukupeza chowonjezera chapamwamba chomwe chimapereka zabwino zomwe mukufuna.
Mlingo ndi kugwiritsa ntchito
Musanaphatikize ufa wa nicotinamide riboside chloride muzochita zanu zatsiku ndi tsiku, ndikofunikira kuti mumvetsetse mlingo woyenera komanso malangizo ogwiritsira ntchito. Ndikofunika kuti muyambe ndi mlingo wocheperako ndikuwonjezeka pang'onopang'ono ngati pakufunika, chifukwa mlingo wapamwamba sungakhale wofanana ndi zotsatira zabwino ndipo zingayambitse zotsatira zoipa. Kuonjezera apo, chonde ganizirani kukaonana ndi katswiri wa zaumoyo kuti mudziwe mlingo womwe uli woyenera pa zolinga zanu zaumoyo ndi zosowa zanu.
Zopindulitsa zomwe zingatheke ndi kulingalira
Nicotinamide Riboside Chloride Powder nthawi zambiri imadziwika chifukwa cha zopindulitsa zake, kuphatikiza kuthandizira mphamvu, ntchito ya mitochondrial, komanso thanzi lonse la ma cell. Kafukufuku akuwonetsa kuti zitha kukhudzanso ukalamba komanso matenda okhudzana ndi ukalamba.
Chitetezo ndi njira zodzitetezera
Monga momwe zilili ndi zowonjezera zilizonse, ndikofunikira kuika chitetezo patsogolo ndikumvetsetsa njira zodzitetezera. Ngakhale nicotinamide riboside chloride nthawi zambiri imalekerera bwino, anthu ena amatha kukhala ndi zotsatirapo zochepa, monga kusapeza bwino m'mimba. Kuonjezera apo, ngati muli ndi vuto linalake kapena mukumwa mankhwala, onetsetsani kuti mwawonana ndi dokotala musanagwiritse ntchito chowonjezera ichi kuti muwonetsetse kuti ndizotetezeka komanso zoyenera pazochitika zanu.
Sankhani ogulitsa odalirika
Mukamagula Nicotinamide Riboside Chloride Powder, ndikofunikira kusankha wodalirika yemwe amaika patsogolo mtundu, kuwonekera, komanso kukhutira kwamakasitomala. Yang'anani makampani omwe amapereka zambiri za njira zawo zopangira, kupeza, ndi kuyesa kwa chipani chachitatu. Kuphatikiza apo, lingalirani zowerenga ndemanga zamakasitomala ndikupeza malingaliro kuchokera kwa odalirika kuti muwonetsetse kuti mukugula kuchokera kwa ogulitsa odalirika komanso odalirika.
Suzhou Myland Pharm & Nutrition Inc. yakhala ikuchita bizinesi yazakudya zopatsa thanzi kuyambira 1992. Ndi kampani yoyamba ku China kupanga ndi kugulitsa zokolola za mphesa.
Pokhala ndi zaka 30 zachidziwitso komanso motsogozedwa ndiukadaulo wapamwamba komanso njira yokongoletsedwa kwambiri ya R&D, kampaniyo yapanga zinthu zambiri zopikisana ndikukhala kampani yowonjezera ya sayansi ya moyo, kaphatikizidwe kazinthu ndi ntchito zopanga.
Kuphatikiza apo, Suzhou Myland Pharm & Nutrition Inc. ndiwopanganso zolembedwa ndi FDA. Zothandizira zamakampani za R&D, malo opangira, ndi zida zowunikira ndi zamakono komanso zogwira ntchito zambiri ndipo zimatha kupanga mankhwala kuchokera ku ma milligrams mpaka matani pamlingo, ndikutsata miyezo ya ISO 9001 ndi kufotokozedwa kwa GMP.
Q: Kodi nicotinamide riboside chloride powder ndi chiyani?
A: Nicotinamide Riboside Chloride Powder ndi mtundu wa vitamini B3 womwe waphunziridwa chifukwa cha kuthekera kwake kuthandizira kupanga mphamvu zama cell ndi metabolism. Nthawi zambiri amagwiritsidwa ntchito ngati chakudya chothandizira kulimbikitsa thanzi labwino komanso thanzi.
Q: Kodi ndi phindu lanji la nicotinamide riboside chloride powder?
A: Ubwino wina wa Nicotinamide Riboside Chloride Powder ungaphatikizepo kuthandizira ntchito ya mitochondrial, kulimbikitsa ukalamba wathanzi, komanso kupititsa patsogolo kupirira komanso kugwira ntchito kwathupi. Zingathandizenso kuthandizira chidziwitso komanso thanzi labwino la ma cell.
Q: Kodi ndingagule kuti nicotinamide riboside chloride powder?
A: Nicotinamide Riboside Chloride powder imapezeka kuchokera kwa ogulitsa osiyanasiyana ndi masitolo a pa intaneti. Pogula chowonjezera ichi, ndikofunika kusankha gwero lodziwika bwino kuti mutsimikizire ubwino ndi chitetezo.
Chodzikanira: Nkhaniyi ndi yachidziwitso chokhacho ndipo siyenera kuwonedwa ngati upangiri wachipatala. Zina mwazolemba zamabulogu zimachokera pa intaneti ndipo sizodziwika. Webusaitiyi ili ndi udindo wokonza, kusanja ndi kusintha zolemba. Cholinga chopereka zambiri sikutanthauza kuti mukugwirizana ndi maganizo ake kapena kutsimikizira kuti zomwe zili m'nkhaniyi ndi zoona. Nthawi zonse funsani dokotala musanagwiritse ntchito zowonjezera zowonjezera kapena kusintha ndondomeko yanu yachipatala.
Nthawi yotumiza: Aug-14-2024
