Chakudya chowonjezera - Chinthu chatsopano chothandizira kukhala ndi moyo wautali komanso woletsa ukalamba: Calcium Alpha-ketoglutarate

Calcium Alpha ketoglutarate (AKG) ndi metabolite yapakati ya tricarboxylic acid cycle ndipo imagwira ntchito popanga ma amino acid, mavitamini, ndi ma organic acid ndi kagayidwe ka mphamvu. Itha kugwiritsidwa ntchito ngati chowonjezera pazakudya ndipo ingagwiritsidwe ntchito kwambiri. Kuphatikiza pa ntchito zake zamoyo m'thupi la munthu, calcium alpha-ketoglutarate imagwiritsidwanso ntchito kwambiri m'munda wamankhwala ndipo yakhala gawo lofunikira la zinthu zambiri zaumoyo ndi mayankho azachipatala.

Momwe calcium alpha-ketoglutarate imagwirira ntchito

Choyamba,calcium alpha-ketoglutarateimagwira ntchito yofunika kwambiri pa kagayidwe ka mphamvu. Monga chinthu chapakati pa kayendedwe ka tricarboxylic acid (TCA cycle), calcium α-ketoglutarate imatenga nawo mbali popanga mphamvu mkati mwa maselo. Kudzera mu kayendedwe ka TCA, michere monga chakudya, mafuta, ndi mapuloteni imasungunuka ndikuwola kuti ipange ATP (adenosine triphosphate) kuti ipereke mphamvu ku maselo. Monga chinthu chofunikira kwambiri pa kayendedwe ka TCA, calcium α-ketoglutarate imatha kulimbikitsa kagayidwe ka mphamvu m'maselo, kuwonjezera mphamvu m'thupi, kuthandiza kulimbitsa mphamvu ndi kupirira, komanso kulimbitsa kutopa kwakuthupi.

Kachiwiri, calcium α-ketoglutarate imagwira ntchito yofunika kwambiri pa kagayidwe ka amino acid. Ma amino acid ndi mayunitsi oyambira a mapuloteni, ndipo calcium α-ketoglutarate imagwira ntchito pakusintha ndi kagayidwe ka amino acid. Posintha ma amino acid kukhala ma metabolites ena, calcium α-ketoglutarate imasinthasintha ndi ma amino acid kuti ipange ma amino acid atsopano kapena ma α-keto acid, motero imayang'anira bwino ndikugwiritsa ntchito ma amino acid. Kuphatikiza apo, calcium α-ketoglutarate ingathenso kugwira ntchito ngati gawo la okosijeni la ma amino acid, kutenga nawo mbali mu kagayidwe ka okosijeni ka ma amino acid, ndikupanga mphamvu ndi carbon dioxide. Chifukwa chake, calcium α-ketoglutarate ndi yofunika kwambiri pakusunga homeostasis ya ma amino acid ndi kagayidwe ka mapuloteni m'thupi.

Kuphatikiza apo, calcium alpha-ketoglutarate imagwira ntchito ngati antioxidant yomwe imachotsa ma free radicals ndikuteteza maselo ku kuwonongeka kwa okosijeni. Nthawi yomweyo, calcium α-ketoglutarate imathanso kuwongolera magwiridwe antchito a chitetezo chamthupi, kulimbikitsa kuyambika ndi kuchulukana kwa maselo a chitetezo chamthupi, ndikuwonjezera kukana kwa thupi ku matenda ndi matenda. Chifukwa chake, calcium α-ketoglutarate ndi yofunika kwambiri pakusunga chitetezo chamthupi komanso kukana matenda.

Kafukufuku wokhudza zotsatira za ukalamba

Ukalamba umatikhudza tonse ndipo ndi chinthu chomwe chimayambitsa matenda ambiri, ndipo malinga ndi ziwerengero za makampani a Medicare, mwayi wokhala ndi matenda umawonjezeka ndi ukalamba. Pofuna kuchepetsa ukalamba ndikuchepetsa bwino chiopsezo cha matenda, kafukufuku wapeza chinthu chotetezeka komanso chogwira ntchito chomwe chingakhudze ukalamba - calcium alpha-ketoglutarate.

Calcium alpha-ketoglutarate ndi metabolite yofunika kwambiri m'thupi lathu, yomwe imadziwika ndi gawo la selo mu kayendedwe ka Krebs, kayendedwe kofunikira pakuwotchedwa kwa mafuta acids ndi amino acids, zomwe zimathandiza mitochondria kupanga ATP (ATP ndiye gwero la mphamvu la maselo).

Izi zimaphatikizapo kudzaza njira ya calcium alpha-ketoglutarate, kotero calcium alpha-ketoglutarate ikhozanso kusinthidwa kukhala glutamate kenako kukhala glutamine, yomwe ingathandize kulimbikitsa kapangidwe ka mapuloteni ndi collagen (collagen ndi puloteni ya ulusi yomwe imapanga 1/3 ya mapuloteni onse m'thupi ndipo imathandizira thanzi la mafupa, khungu ndi minofu).

Ponce De Leon Health, Inc., kampani yofufuza za moyo wautali yomwe imayang'ana kwambiri pakusintha ukalamba wa majini, idachita kafukufuku wolamulidwa wa zaka zambiri wa calcium alpha-ketoglutarate pa mbewa zapakati ndipo idapeza kuti moyo wa mbewa zomwe zili mgulu loyesera unawonjezeka ndi 12%. Chofunika kwambiri, kufooka kunachepetsedwa ndi 46% ndipo moyo wathanzi unawonjezeka ndi 41%. Umboni ukuwonetsa kuti kuwonjezera alpha-ketoglutarate sikungowonjezera moyo komanso kukulitsa moyo wathanzi kwambiri.

Calcium α-ketoglutarate, monga chowonjezera cha zakudya chogwira ntchito zambiri, ili ndi mwayi waukulu wogwiritsidwa ntchito muzinthu zothandizira zaumoyo. Ntchito zake zosiyanasiyana zamoyo monga antioxidant, anti-ukalamba, malamulo a chitetezo chamthupi komanso kagayidwe ka amino acid zimapangitsa kuti ikhale chida champhamvu chowongolera thanzi la anthu. Chifukwa cha kuchuluka kwa chidziwitso cha chisamaliro chaumoyo komanso kuzama kwa kafukufuku wasayansi, akukhulupirira kuti kugwiritsa ntchito calcium ya α-ketoglutarate m'munda wazinthu zothandizira zaumoyo kudzalandira chidwi ndi chitukuko chochulukirapo.