Zakudya zowonjezera-Zatsopano za moyo wautali komanso zoletsa kukalamba: Calcium Alpha-ketoglutarate

Calcium Alpha ketoglutarate (AKG) ndi metabolite yapakatikati ya tricarboxylic acid cycle ndipo imatenga nawo gawo popanga ma amino acid, mavitamini, ndi ma organic acid ndi metabolism yamphamvu. Itha kugwiritsidwa ntchito ngati chowonjezera chazakudya ndipo imakhala ndi chiyembekezo chogwiritsa ntchito. Kuphatikiza pa ntchito zake zachilengedwe m'thupi la munthu, calcium alpha-ketoglutarate imagwiritsidwanso ntchito kwambiri m'munda wamankhwala ndipo yakhala gawo lofunikira pazamankhwala ambiri komanso mayankho azachipatala.

Momwe calcium alpha-ketoglutarate imagwirira ntchito

Choyamba,calcium alpha-ketoglutarateimagwira ntchito yofunika kwambiri mu metabolism yamphamvu. Monga chinthu chapakatikati cha tricarboxylic acid cycle (TCA), calcium α-ketoglutarate imatenga nawo gawo pakupanga mphamvu zamagetsi. Kupyolera mu kayendetsedwe ka TCA, zakudya monga chakudya, mafuta, ndi mapuloteni amapangidwa ndi okosijeni ndikuwonongeka kuti apange ATP (adenosine triphosphate) kuti apereke mphamvu kwa maselo. Monga gawo lapakati lofunikira pakuyenda kwa TCA, calcium α-ketoglutarate imatha kulimbikitsa kagayidwe kazinthu zama cell, kuwonjezera mphamvu ya thupi, kuthandizira kulimbitsa thupi ndi kupirira, komanso kutopa kwathupi.

Kachiwiri, calcium α-ketoglutarate imagwira ntchito yofunika kwambiri mu metabolism ya amino acid. Ma amino acid ndi magawo oyambira a mapuloteni, ndipo calcium α-ketoglutarate imakhudzidwa ndikusintha ndi kagayidwe ka amino acid. Posintha ma amino acid kukhala ma metabolites ena, calcium α-ketoglutarate imadutsa ndi ma amino acid kuti ipange ma amino acid atsopano kapena ma α-keto acid, motero imayendetsa bwino komanso kugwiritsa ntchito ma amino acid. Kuphatikiza apo, calcium α-ketoglutarate imathanso kukhala gawo la oxidation la amino acid, kutenga nawo gawo mu metabolism ya oxidative ya amino acid, ndikupanga mphamvu ndi carbon dioxide. Chifukwa chake, calcium α-ketoglutarate ndiyofunikira kwambiri pakusunga homeostasis ya amino acid ndi protein metabolism m'thupi.

Kuphatikiza apo, calcium alpha-ketoglutarate imagwira ntchito ngati antioxidant yomwe imachotsa ma free radicals ndikuteteza maselo kuti asawonongeke ndi okosijeni. Panthawi imodzimodziyo, calcium α-ketoglutarate ingathenso kulamulira ntchito ya chitetezo cha mthupi, kulimbikitsa kuyambitsa ndi kufalikira kwa maselo a chitetezo cha mthupi, komanso kupititsa patsogolo kukana kwa thupi ku matenda ndi matenda. Chifukwa chake, calcium α-ketoglutarate ndiyofunikira kwambiri pakusunga chitetezo chathupi komanso kukana matenda.

Kafukufuku wokhudza ukalamba

Kukalamba kumatikhudza tonsefe ndipo ndizomwe zimayambitsa matenda ambiri, ndipo malinga ndi kuchuluka kwa makampani a Medicare, mwayi wokhala ndi matenda ukuwonjezeka ndi zaka. Pofuna kuchepetsa ukalamba komanso kuchepetsa chiopsezo cha matenda, kafukufuku wapeza chinthu chotetezeka komanso chamoyo chomwe chingakhudze ukalamba - calcium alpha-ketoglutarate.

Calcium alpha-ketoglutarate ndi metabolite yofunikira m'thupi lathu, yomwe imadziwika ndi gawo la cell mu Krebs cycle, cycle yofunika kuti makutidwe ndi okosijeni amafuta acids ndi amino acid, kulola mitochondria kupanga ATP (ATP ndiye gwero lamphamvu la maselo).

Izi zimaphatikizapo kukweza kwa calcium alpha-ketoglutarate, kotero kuti calcium alpha-ketoglutarate imathanso kusinthidwa kukhala glutamate kenako kukhala glutamine, yomwe ingathandize kulimbikitsa kaphatikizidwe ka mapuloteni ndi kolajeni (collagen ndi mapuloteni a fibrous omwe amapanga 1/3 ya mapuloteni onse m'thupi ndikuthandizira kuthandizira thanzi la mafupa, khungu ndi minofu).

Ponce De Leon Health, Inc., kampani yofufuza za moyo wautali yomwe imayang'ana kwambiri pakubwezeretsa kukalamba kwa majini, idachita kafukufuku woyendetsedwa ndi calcium alpha-ketoglutarate pazaka zapakati pa mbewa zapakati ndipo adapeza kuti nthawi yamoyo wa mbewa mgulu loyesera idakwera 12%. Chofunika koposa, kufooka kudachepetsedwa ndi 46% ndipo moyo wathanzi udakwera ndi 41%. Umboni ukuwonetsa kuti alpha-ketoglutarate supplementation sikungowonjezera moyo komanso kukulitsa nthawi yathanzi mokulirapo.

Calcium α-ketoglutarate, monga chowonjezera chamagulu ambiri, chili ndi chiyembekezo chogwiritsa ntchito pazinthu zachipatala. Ntchito zake zosiyanasiyana zachilengedwe monga antioxidant, anti-aging, regulation chitetezo ndi amino acid metabolism zimapangitsa kuti ikhale chida champhamvu chothandizira thanzi la munthu. Ndi chidziwitso chowonjezereka cha chisamaliro chaumoyo komanso kuzama kwa kafukufuku wa sayansi, akukhulupirira kuti kugwiritsa ntchito α-ketoglutarate calcium m'munda wa mankhwala osamalira thanzi kudzalandira chidwi ndi chitukuko.