N-Boc-O-Benzyl-D-serine wopanga ufa CAS No.:47173-80-8 98% chiyero min. kwa Apakati
Product Parameters
Dzina la malonda | N-Boc-O-Benzyl-D-serine |
Dzina lina | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R) -2-amino-3-benzyloxypropionic asidi; Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
CAS No. | 47173-80-8 |
Molecular formula | C15H21NO5 |
Kulemera kwa maselo | 295.33 |
Chiyero | 98% |
Kulongedza | 1kg / thumba; 25kg / ng'oma |
Kugwiritsa ntchito | Apakati |
Chiyambi cha malonda
N-Boc-O-Benzyl-D-serine ndi gulu lomwe lapeza chidwi kwambiri pazachilengedwe komanso kafukufuku wamankhwala. Pawiri Izi, amatchedwanso Boc-D-serine, ndi yochokera kwa amino asidi D-serine ndipo chimagwiritsidwa ntchito synthesis zosiyanasiyana mankhwala ndi mamolekyu bioactive. N-Boc-O-Benzyl-D-serine ndi ufa wa crystalline woyera mpaka woyera womwe umasungunuka pang'ono m'madzi ndi kusungunuka mu zosungunulira za organic monga methanol ndi ethanol. Ndiwochokera ku D-serine, yomwe si proteinogenic amino acid yomwe imagwira ntchito yofunika kwambiri pakatikati pa mitsempha yamagazi monga co-agonist wa N-methyl-D-aspartate (NMDA) receptor. Magulu a N-Boc (tert-butoxycarbonyl) ndi O-Benzyl omwe ali m'gululi amagwira ntchito ngati magulu oteteza, kulola kuti amino acid azitha kusankhapo pakupanga mankhwala.N-Boc-O-Benzyl-D-serine makamaka amagwiritsidwa ntchito ngati chomanga mu synthesis wa peptides ndi peptidomimetics. Ma peptides ndi maunyolo achidule a amino acid omwe amagwira ntchito zosiyanasiyana pazachilengedwe ndipo ali ndi chidwi chachikulu pakupeza mankhwala ndi chitukuko. Pophatikizira N-Boc-O-Benzyl-D-serine muzotsatira za peptide, akatswiri amankhwala amatha kusintha mawonekedwe ndi zochitika za ma peptide omwe amabwera, ndikupangitsa kuti ikhale chida chofunikira pakupanga kwazinthu zatsopano zamankhwala. Komanso, N-Boc-O-Benzyl-D-serine amagwiritsidwa ntchito pokonzekera mankhwala ophatikizika ndi mankhwala opangira mankhwala (APIs). Kugwiritsiridwa ntchito kwake kosunthika komanso kugwirizana ndi machitidwe osiyanasiyana a mankhwala kumapangitsa kuti ikhale yofunidwa kwambiri mu kaphatikizidwe ka mamolekyu ovuta omwe ali ndi mphamvu zochiritsira.
Mbali
(1) Chiyero chachikulu: N-Boc-O-Benzyl-D-serine imatha kupeza zinthu zoyera kwambiri poyeretsa njira zopangira. Kuyeretsedwa kwakukulu kumatanthauza kukhalapo kwa bioavailability ndi zotsatira zochepa.
(2) Chitetezo: Kutetezedwa kwambiri, kusakhala ndi zovuta zochepa.
(3) Kukhazikika: N-Boc-O-Benzyl-D-serine ili ndi kukhazikika bwino ndipo imatha kusunga ntchito yake ndi zotsatira zake pansi pa malo osiyanasiyana ndi malo osungira.
Mapulogalamu
Kuphatikizika kwa N-Boc-O-Benzyl-D-serine mu mamolekyu a mankhwala kwawonetsedwa kuti kumapereka zinthu zofunika za pharmacokinetic ndi pharmacodynamic. Peptidomimetics yochokera ku N-Boc-O-Benzyl-D-serine yawonetsa kukhazikika, bioavailability, ndi chandamale chandamale, zomwe zimawapangitsa kukhala odalirika ochiza matenda osiyanasiyana, kuphatikiza khansa, matenda opatsirana, ndi matenda amisempha. kusintha mosankha gulu la N-Boc-O-Benzyl-D-serine limalola kukonzanso kwabwino kwa ofuna kugwiritsa ntchito mankhwala osokoneza bongo, kukulitsa mphamvu zawo komanso mbiri yachitetezo.