J-147 wopanga ufa CAS No.: 1146963-51-0 99.0% chiyero min. kwa zowonjezera zowonjezera
Product Parameters
| Dzina la malonda | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Dzina lina | J-147, J147 |
| CAS No. | 1146963-51-0 |
| Molecular formula | Chithunzi cha C18H17F3N2O2 |
| Kulemera kwa maselo | 350.33 |
| Chiyero | 99% |
| Maonekedwe | White ufa |
| Kulongedza | 1kg pa thumba |
| Kugwiritsa ntchito | mankhwala a nootropic |
Chiyambi cha Zamalonda
J-147 ndi neuroprotectant yamphamvu kwambiri pakamwa yomwe imachokera makamaka ku curcumin, yomwe imagwira ntchito mu turmeric. Mosiyana ndi curcumin, imadutsa chotchinga cha magazi ndi ubongo bwino kwambiri. Pakati pawo, J-147 imagwira ntchito pomanga ku ATP synthase. Kuchuluka kwa ATP kumayenderana ndi ukalamba. Kuphatikiza pa kuchuluka kwa ma neurotransmitters NGF ndi BDNF, J-147 imatha kuwongolera izi. Kuphatikiza apo, J-147 imaletsa monoamine oxidase B ndi dopamine transporter. Imalimbikitsa kukula kwa ubongo mwa kuwonjezera kuchuluka kwa mitsempha ya kukula kwa mitsempha (NGF) ndi ubongo-derived neurotrophic factor (BDNF). Chofunika kwambiri, J-147 ikhoza kulimbikitsa kukula kwa maselo atsopano a mitsempha, kupititsa patsogolo luso la ubongo la kuphunzira ndi kukumbukira, komanso kupititsa patsogolo ntchito zamaganizo.
Mbali
(1) Chiyero chachikulu: J-147 imatha kupeza zinthu zoyenga kwambiri poyeretsa njira zopangira. Kuyeretsedwa kwakukulu kumatanthauza kukhalapo kwa bioavailability ndi zotsatira zochepa.
(2) Chitetezo: J-147 yatsimikiziridwa kukhala yotetezeka kwa thupi la munthu.
(3) Kukhazikika: J-147 ili ndi kukhazikika bwino ndipo imatha kusunga ntchito yake ndi zotsatira zake pansi pa malo osiyanasiyana ndi malo osungira.
(4) Yosavuta kuyamwa: J-147 imatha kutengeka mwachangu ndi thupi la munthu, imalowa m'magazi kudzera m'matumbo, ndikugawidwa kumagulu ndi ziwalo zosiyanasiyana.
Mapulogalamu
J-147 ndi gulu lopangira lomwe limagwirira ntchito zake limaphatikizapo kupititsa patsogolo kwa mitochondrial, potero kukhathamiritsa kupanga mphamvu pama cell. J-147 idapangidwa kuti ipititse patsogolo luso la ubongo lokonzanso ndikudziteteza ku kuwonongeka kobwera chifukwa cha ukalamba mwa kukonza magwiridwe antchito a mitochondrial. Kuphatikiza apo, J-147 imawonetsa anti-yotupa komanso antioxidant katundu, kupititsa patsogolo zotsatira zake za neuroprotective. J-147 ikhoza kulimbikitsa kukula kwa maselo atsopano a mitsempha, kupititsa patsogolo luso la ubongo la kuphunzira ndi kukumbukira, ndi kupititsa patsogolo kugwira ntchito kwa chidziwitso.
