Kodi amino acid amasinthidwa kuchokera ku chiyani? Kodi ntchito yake ndi yotani?

Sperminendi gawo lofunikira la polyamine lomwe limapezeka kwambiri mu zamoyo, makamaka zomwe zimagwira ntchito yofunika kwambiri pakukula kwa maselo ndi kukula. Spermine imasinthidwa kuchokera ku amino acid arginine ndi ornithine. Nkhaniyi ifufuza gwero, ntchito ndi kufunika kwa umuna mu zamoyo.

Magwero a Spermine

Kaphatikizidwe ka spermine makamaka zimadalira kagayidwe ka amino zidulo. Choyamba, ornithine ndiye kalambulabwalo wa kaphatikizidwe ka spermine, yemwe amatha kupangidwa ndi decarboxylation reaction ya arginine. Njira yeniyeni ndi iyi:

Arginine imasinthidwa kukhala ornithine: Pansi pa catalysis ya michere, arginine ndi decarboxylated kupanga ornithine.
Kusandulika kwa ornithine kukhala spermine: Ornithine imaphatikizidwanso ndi amino acid (nthawi zambiri amino acid alanine) ndipo, kudzera muzochita zingapo za enzymatic, pamapeto pake imapanga umuna.
Kutembenuka kumeneku sikumangokhudza kagayidwe ka amino acid, komanso kumagwirizana kwambiri ndi kukula kwa maselo, kugawanika ndi kukonza.

Zachilengedwe zotsatira za umuna

Spermine ili ndi ntchito zambiri zofunikira zamoyo m'zamoyo, makamaka kuphatikiza izi:

Kuchulukana kwa ma cell ndi kukula: Spermine imagwira ntchito yofunika kwambiri pakuwongolera kayendedwe ka maselo. Kafukufuku wasonyeza kuti umuna ukhoza kulimbikitsa kukula kwa maselo, makamaka pokonza minofu ndi kusinthika. Imalimbikitsa kugawikana kwa maselo ndi kukula mwa kuwongolera mawonekedwe a mapuloteni okhudzana ndi ma cell.

Antioxidant effect: Spermine imakhala ndi antioxidant katundu, yomwe imatha kuchotsa ma radicals aulere m'thupi ndikuchepetsa kuwonongeka kwa ma cell chifukwa cha kupsinjika kwa okosijeni. Katunduyu amapangitsa kuti umuna ukhale ndi phindu logwiritsa ntchito pochedwetsa kukalamba komanso kupewa matenda okhudzana ndi ukalamba.

Kuwongolera mafotokozedwe a jini: Spermine imatha kuwongolera mawonekedwe a jini pomanga ku DNA ndi RNA. Kuwongolera uku ndikofunikira kwambiri pakugwira ntchito kwa cell komanso momwe thupi limakhalira, makamaka poyankha kukopa kwakunja ndi kupsinjika.

Imalimbikitsa apoptosis: Nthawi zina, umuna ungathenso kulimbikitsa apoptosis (maselo opangidwa ndi maselo), zomwe ndizofunikira kuti ma cell homeostasis akhale ndi thanzi labwino.

Immunomodulation: Spermine imathandizanso kwambiri chitetezo chamthupi. Ikhoza kupititsa patsogolo ntchito ya maselo a chitetezo cha mthupi ndikuthandizira kuti thupi likhale lolimba ku matenda ndi matenda.

Spermine ndi Thanzi

Pamene kafukufuku wokhudza umuna akuya, umboni wochuluka umasonyeza kuti umuna umagwirizana kwambiri ndi matenda osiyanasiyana. Mwachitsanzo, milingo ya umuna imagwirizana kwambiri ndi zomwe zimachitika komanso kukula kwa matenda osiyanasiyana monga ukalamba, matenda amtima ndi khansa.

Kukalamba: Kafukufuku wapeza kuti ma spermine amachepetsa pang'onopang'ono akamakalamba, ndipo spermine supplementation ingathandize kuchepetsa ukalamba komanso kusintha thanzi la okalamba.

Thanzi Lamtima: Spermine imagwira ntchito yoteteza m'mitsempha ya mtima, kupititsa patsogolo ntchito ya endothelial ndi kuchepetsa chiopsezo cha matenda a mtima.

Pomaliza

Monga molekyulu yofunikira yachilengedwe, umuna umachokera makamaka ku metabolism ya amino acid, makamaka kutembenuka kwa arginine ndi ornithine. Spermine imakhala ndi gawo lofunikira pakuchulukira kwa maselo, anti-oxidation, gene expression regulation, etc., ndipo ndiyofunikira pakusunga thanzi ndi ntchito za zamoyo. Ndi kafukufuku wozama wa umuna, zambiri zokhudza udindo wake pa thanzi ndi matenda zikhoza kuzindikirika m'tsogolomu, kupereka malingaliro atsopano ndi njira zopewera ndi kuchiza matenda okhudzana ndi matenda.

Pomvetsetsa chiyambi ndi ntchito ya umuna, tikhoza kumvetsetsa kufunika kwake muzochitika za moyo ndikupereka maziko a sayansi olimbikitsa thanzi ndi kuchedwetsa kukalamba. Tikukhulupirira kuti kafukufuku wamtsogolo adzawululanso momwe angagwiritsire ntchito umuna ndikuthandizira kwambiri thanzi laumunthu.

Chodzikanira: Webusaitiyi imasindikiza kapena kusindikizanso nkhaniyi ndi cholinga chongopereka ndikugawana zambiri, ndipo sizikutanthauza kuti ikugwirizana ndi malingaliro ake kapena kutsimikizira mafotokozedwe ake. Ngati pali cholakwika polemba gwero kapena kuphwanya ufulu wanu walamulo, chonde lemberani patsamba lino ndi umboni kuti ndinu mwini wake, ndipo tidzakonza kapena kuchotsa nthawi yake. Zikomo.