Pamene anthu amadera nkhawa kwambiri za thanzi lawo, Squalene akuyamba kutchuka chifukwa cha mphamvu zake zopatsa mphamvu komanso zoteteza antioxidant. Monga mankhwala opangidwa mwachilengedwe, squalene amagwiritsidwa ntchito kwambiri pazinthu zosamalira khungu, zodzoladzola ndi zakudya zowonjezera zakudya. Pamene kufunikira kwa ogula kwa zinthu zachilengedwe kukukulirakulira, momwemonso kufunikira kwa ufa wapamwamba wa Squalene pamsika.
Squalene (CAS: 111-02-4) ndi madzi amadzimadzi opanda mtundu. Ndi gulu lonse la trans-triterpene lomwe lili ndi mawonekedwe a isoprene ndipo ndi gawo lofunikira panjira ya metabolism ya cholesterol yamunthu. Chofunikira chapakatikati, ma terpenoids amapezeka nthawi zambiri muzakudya zopatsa thanzi komanso zodzoladzola. Squalene imakhulupirira kuti ili ndi maubwino ambiri m'thupi la munthu, kuphatikiza kutsitsa lipids m'magazi, antioxidant, anti-yotupa komanso kulimbikitsa chitetezo chokwanira. Squalene amatha kutenga nawo gawo mu metabolism ngati kalambulabwalo wa kaphatikizidwe ka steroid, ndipo amagwira ntchito yofunika kwambiri pakupanga njira za β-carotene, coenzyme Q10, vitamini D, vitamini E ndi vitamini K1.
Squalene imapezeka kwambiri mu nyama, zomera ndi tizilombo. Amapangidwa mu endoplasmic reticulum ndikusungidwa mu vesicles kapena kusamutsidwa ku nembanemba ya cell kudzera mu vesicles. Chifukwa cha mphamvu zake zamoyo, amagwiritsidwa ntchito kwambiri muzakudya ndi zodzoladzola. Madera amakampani. Squalene imapezeka m'zakudya zambiri, zomwe mafuta a chiwindi cha shark ali ndi kuchuluka kwakukulu, ndipo mafuta ochepa a masamba monga mafuta a azitona ndi mafuta a mpunga amakhalanso ndi squalene yambiri.
Squalene imakhala ndi zotsatira zambiri za bioactive, kuphatikizapo kuwongolera kulekerera kwa hypoxia, kulepheretsa kukula kwa tizilombo toyambitsa matenda, antibacterial ndi anti-yotupa, komanso kuwongolera kagayidwe ka cholesterol. Kuphatikiza apo, imatha kuzimitsa mpweya wa singlet, kuteteza bwino khungu ku lipid peroxidation ndikuteteza maselo ku kuwonongeka kwa okosijeni ku DNA. Izi zikuwonetsanso ntchito zosiyanasiyana zofunika pathupi monga kupewa matenda amtima komanso kukulitsa chitetezo chathupi chamunthu.
Chidziwitso cha ntchito za squalene
1. Antioxidant ntchito
Squalene imatha kuteteza bwino zomwe ma radicals aulere m'thupi la munthu amachita komanso kuchita nawo antioxidant. Molekyu ya squalene imapangidwa ndi ma 6 osagwirizana ndi ma unsaturated awiri omangira ndipo ali ndi mphamvu za antioxidant.
2. Antibacterial ndi anti-inflammatory effects
Squalene ali ndi antibacterial, odana ndi kutupa ndi bactericidal zotsatira ndipo angagwiritsidwe ntchito chapamwamba kupuma thirakiti matenda ndi matenda pakhungu chifukwa mabakiteriya, komanso amayaka, zilonda zapakhungu ndi aphthous matenda. Kafukufuku akuwonetsa kuti squalene imatha kufulumizitsa machiritso a mabala ndi mabala. Ma anti-inflammatory and antioxidant katundu wake amathandizira kuchira msanga, ndikupangitsa kuti ikhale yowonjezera pagulu lililonse loyamba lothandizira
3. Free radical mkangaziwisi, chitetezo kuwongola
Squalene ali ndi mphamvu zowononga zowononga zaulere ndipo amatenga gawo lofunikira polimbikitsa kagayidwe ka anthu. Poyambitsa kagayidwe kake, squalene imathandizira kuyamwa kwa thupi ndikugwiritsa ntchito bwino michere, potero kulimbikitsa thanzi. Monga chowonjezera chazakudya, squalene imagwiritsidwa ntchito pazinthu zosiyanasiyana zaumoyo, monga zopatsa thanzi, zakudya zathanzi, ndi zakumwa zogwira ntchito. Kafukufuku ndi kugwiritsa ntchito squalene akukulirakulira nthawi zonse, kupatsa anthu mwayi wopeza mapindu azaumoyo kudzera muzakudya.
4. Moisturizing ndi antioxidant
Squalene ili ndi maubwino angapo pakhungu, kuphatikiza chitetezo ku radiation ya UV ndi antioxidant. Imawongolera mawonekedwe a khungu, imachepetsa pores ndi makwinya, komanso imanyowetsa khungu popanda kuyambitsa mkwiyo. Kuyesera kwa amayi opitilira zaka 50 kunawonetsa kuti kumwa squalene kumatha kuchepetsa makwinya kumaso ndikuwongolera zotupa kumaso ndi mtundu. Kuonjezera apo, squalene ikhoza kuonjezera ntchito ya antioxidant enzyme ya khungu, ndipo zotsatira zake zimakhala zabwino kwambiri kuposa vitamini E. Chifukwa cha zotsatira zake zabwino kwambiri, zodzikongoletsera zina zodziwika bwino zakhala zikugwiritsidwa ntchito pazinthu zosamalira khungu ndi tsitsi monga hydrating serums ndi chisamaliro cha khungu. mafuta.
3. Squalene makampani ntchito
1). Squalene ndi mankhwala ake a hydrogenated ndi otchuka chifukwa cha ntchito zosiyanasiyana zodzoladzola. Squalene ili ndi maubwino angapo pakhungu, kuphatikiza chitetezo ku radiation ya UV ndi antioxidant. Imawongolera mawonekedwe a khungu, imachepetsa pores ndi makwinya, komanso imanyowetsa khungu popanda kuyambitsa mkwiyo.
2). Monga mafuta achilengedwe, squalene amagwiritsidwa ntchito kwambiri ngati chonyamulira chamankhwala chothandizira kuti atulutse mankhwala. Emulsion mankhwala okhala ndi squalene akhoza kuwonjezera theka la moyo wa mankhwala.
3). Squalene yasonyeza mphamvu zambiri zogwiritsira ntchito kafukufuku wamankhwala: m'maselo a HepG2, imayang'ana njira yochepetsera mafuta m'thupi mwa kulepheretsa kufalikira kwa maselo ndi kuwonjezereka kwa LDLR; chachiwiri, kafukufuku wa ma cell docking akuwonetsa kuti squalene ikhoza kukhala ndi gawo mu chithandizo cha khansa yapakhungu kuti igwire ntchito; Pomaliza, pakuphatikizidwa mu PLGA NPs, kuyamwa kwa ma cell mu mafuta a azitona kumakhala bwino, ndipo kumatha kukhalabe ndi thanzi la cell ndikukana kupsinjika kwa okosijeni.
4). Monga chowonjezera chazakudya, squalene yakopa chidwi kwambiri ndipo yawerengedwa kwambiri chifukwa cha gawo lake popewa matenda amtima, khansa ndi matenda ena.
Kodi Mungagule Kuti Squalene?
Zofunika Kwambiri Posankha Wopereka Squalene
1. Makhalidwe abwino
Posankha wogulitsa, chinthu choyamba choyenera kuganizira ndi khalidwe la mankhwala. Kuyeretsa kwakukulu kwa ufa wa Squalene kumatsimikizira ntchito yake yachilengedwe komanso yogwira mtima. Ufa wa Squalene woperekedwa ndi Suzhou Myland wayesedwa mosamalitsa kuti awonetsetse kuti gulu lililonse lazinthu likukwaniritsa miyezo yapadziko lonse lapansi ndipo lili ndi chitsimikizo.
2. Mphamvu zopanga
Kuthekera kopanga kwa wopanga kumakhudza mwachindunji nthawi yake komanso kukhazikika kwazinthu. Suzhou Myland ili ndi zida zopangira zida zapamwamba komanso ukadaulo womwe ungakwaniritse zosowa zopanga anthu ambiri, kuwonetsetsa kuti makasitomala atha kupeza zinthu zomwe amafunikira munthawi yomwe akuzifuna.
3. R&D luso
Wothandizira wabwino kwambiri nthawi zambiri amakhala ndi gulu lolimba la R&D lomwe limatha kupitiliza kukonza zinthu ndikupanga zatsopano. Suzhou Myland yapeza zambiri pakufufuza ndi kugwiritsa ntchito Squalene ndipo imatha kupatsa makasitomala chithandizo chaukadaulo ndi mayankho.
4. Utumiki Wamakasitomala
Utumiki wabwino wamakasitomala ndi chinthu chomwe sichinganyalanyazidwe posankha wogulitsa. Suzhou Myland imayang'ana kwambiri kulumikizana ndi makasitomala ndipo imatha kupereka chithandizo chamunthu malinga ndi zosowa zamakasitomala kuonetsetsa kuti makasitomala amapeza chidziwitso chabwino kwambiri pakugula.
5. Chitsimikizo ndi Kutsatira
Kuwonetsetsa kuti ogulitsa ali ndi ziphaso zoyenera komanso kutsata ndizofunikira pakusankha. Suzhou Myland ndi ISO certification ndipo ikutsatira miyezo ya GMP (Good Manufacturing Practice), kuwonetsetsa kuti zogulitsa zake zimatsata dongosolo lokhazikika loyang'anira pakupanga.
Pomaliza
Kusankha wopereka Squalene woyenera ndikofunikira pakuwonetsetsa kuti zinthu zili bwino komanso chitetezo. Suzhou Myland yakhala chisankho chodalirika pamsika ndi zinthu zake zoyera kwambiri, kuwongolera bwino kwambiri komanso ntchito zamaluso. Kaya ndinu opanga zinthu zosamalira khungu, kampani yodzikongoletsera kapena mukufuna makampani ena, Suzhou Myland ikhoza kukupatsani ufa wapamwamba kwambiri wa Squalene kuti akuthandizeni thanzi lanu ndi chitukuko cha ntchito. Kuti mumve zambiri, chonde pitani patsamba lovomerezeka la Suzhou Mailun Biology.
Chodzikanira: Nkhaniyi ndi yachidziwitso chokhacho ndipo siyenera kuwonedwa ngati upangiri wachipatala. Zina mwazolemba zamabulogu zimachokera pa intaneti ndipo sizodziwika. Webusaitiyi ili ndi udindo wokonza, kusanja ndi kusintha zolemba. Cholinga chopereka zambiri sikutanthauza kuti mukugwirizana ndi maganizo ake kapena kutsimikizira kuti zomwe zili m'nkhaniyi ndi zoona. Nthawi zonse funsani dokotala musanagwiritse ntchito zowonjezera zowonjezera kapena kusintha ndondomeko yanu yachipatala.
Nthawi yotumiza: Oct-25-2024