Kodi Beta-Hydroxybutyrate (BHB) & Izi ndi Zomwe Muyenera Kudziwa

Beta-hydroxybutyrate (BHB) ndi imodzi mwamatupi atatu akuluakulu a ketone omwe amapangidwa ndi chiwindi panthawi ya kudya kwamafuta ochepa, kusala kudya, kapena kuchita masewera olimbitsa thupi kwa nthawi yayitali. Matupi ena awiri a ketone ndi acetoacetate ndi acetone. BHB ndi thupi la ketone lochuluka kwambiri komanso lothandiza kwambiri, lomwe limalola kuti likhale lofunika kwambiri m'thupi la mphamvu ya metabolism, makamaka pamene glucose akusowa. Beta-hydroxybutyrate (BHB) ndi thupi lamphamvu la ketone lomwe limagwira ntchito yofunika kwambiri mu metabolism yamphamvu, makamaka panthawi ya ketosis. Phindu lake limapitilira kupanga mphamvu kuti lipereke chidziwitso, kasamalidwe ka kulemera, ndi zotsutsana ndi kutupa. Kaya mukutsatira zakudya za ketogenic kapena mukuyang'ana kuti mukhale ndi thanzi labwino la metabolism, ndikofunikira kumvetsetsa BHB ndi ntchito zake.

Kodi beta-hydroxybutyrate (BHB) ndi chiyani?

Beta-hydroxybutyrate (BHB) ndi imodzi mwa matupi atatu a ketone opangidwa ndi chiwindi pamene pali kusowa kwa chakudya. (Amadziwikanso kuti 3-hydroxybutyrate kapena 3-hydroxybutyric acid kapena 3HB.)

Nazi mwachidule matupi a ketone omwe chiwindi chimatha kupanga:

Beta-Hydroxybutyrate (BHB). Ichi ndiye ketone yochuluka kwambiri m'thupi, yomwe imakhala pafupifupi 78% ya matupi a ketone m'magazi. BHB ndiye chomaliza cha ketosis.

Acetoacetate. Mtundu uwu wa matupi a ketone umakhala pafupifupi 20% ya matupi a ketone m'magazi. BHB imapangidwa kuchokera ku acetoacetate ndipo singapangidwe ndi thupi mwanjira ina iliyonse. Ndikofunika kuzindikira kuti acetoacetate ndi yosakhazikika kuposa BHB, kotero kuti acetoacetate ikhoza kusinthika kukhala acetone musanayambe zomwe zimatembenuza acetoacetate ku BHB.

acetone. Ma ketoni ocheperako; amawerengera pafupifupi 2% ya matupi a ketone m'magazi. Sagwiritsidwa ntchito ngati mphamvu ndipo amachotsedwa m'thupi nthawi yomweyo.

Zonse BHB ndi acetone zimachokera ku acetoacetate, komabe, BHB ndiyo ketone yoyamba yomwe imagwiritsidwa ntchito pa mphamvu chifukwa imakhala yokhazikika komanso yochuluka, pamene acetone imatayika kupyolera mu kupuma ndi thukuta.

Zonse zomwe muyenera kudziwa zokhudza BHB

Pa ketosis, mitundu itatu yayikulu ya matupi a ketone imatha kupezeka m'magazi:

●acetoacetate

●β-Hydroxybutyrate (BHB)

● Acetone

BHB ndiye ketone yothandiza kwambiri, yothandiza kwambiri kuposa shuga. Sikuti zimangopereka mphamvu zambiri kuposa shuga, zimalimbananso ndi kuwonongeka kwa okosijeni, zimachepetsa kutupa, komanso zimathandizira kugwira ntchito kwa ziwalo, makamaka ubongo.

Ngati mukufuna kuchepetsa thupi, kupititsa patsogolo ntchito zamaganizo, ndikuwonjezera moyo wanu, BHB ndiyo njira yanu yabwino kwambiri.

Njira yosavuta yowonjezerera milingo ya BHB ndikutenga ma ketoni akunja ndi mafuta a MCT. Komabe, zowonjezera izi zitha kungowonjezera matupi a ketone mpaka thupi lanu lizigwiritsa ntchito.

Kuti mulimbikitse kupanga kwa BHB kwa nthawi yayitali m'njira yathanzi, muyenera kutsatira zakudya za ketogenic.

Mukamagwiritsa ntchito zakudya, mutha kugwiritsa ntchito njira zingapo kuti muwonjezere kupanga ketone, kuphatikiza:

● Muzichepetsa magilamu 15 patsiku kwa sabata yoyamba.

●Chepetsani masitolo a glycogen pochita masewera olimbitsa thupi kwambiri.

● Gwiritsani ntchito masewera olimbitsa thupi otsika kwambiri kuti muwonjezere kuwotcha mafuta ndi kupanga matupi a ketone.

● Tsatirani dongosolo losala kudya.

Mukafuna mphamvu zowonjezera, tengani MCT Mafuta owonjezera ndi / kapena BHB Keto Salts

Chifukwa chiyani thupi lanu likufuna BHB? kuchokera ku kawonedwe kachisinthiko

Kodi thupi lanu silikumva ngati likuchita khama kwambiri kuti lipange ndikugwiritsa ntchito ma ketoni ochepa? Kodi siziwotcha mafuta? Chabwino, inde ndi ayi.

Mafuta amafuta acids amatha kugwiritsidwa ntchito ngati mafuta m'maselo ambiri, koma ku ubongo, amachedwa kwambiri. Ubongo umafunikira magwero amphamvu omwe amagwira ntchito mwachangu, osati mafuta ochepetsa mphamvu ngati mafuta.

Chotsatira chake, chiŵindi chinapanga mphamvu yosintha mafuta a asidi kukhala matupi a ketone—magwero ena amphamvu a ubongo pamene shuga ndi wosakwanira. Inu akatswiri a sayansi kunjako mungakhale mukuganiza kuti: "Kodi sitingagwiritse ntchito gluconeogenesis kuti tipereke shuga ku ubongo?"

Inde, tingathe—koma pamene ma carbs ali otsika, tiyenera kuthyola pafupifupi magalamu a 200 (pafupifupi 0.5 pounds) a minofu patsiku ndi kuwasandutsa shuga kuti apange ubongo wathu.

Powotcha matupi a ketoni kuti akhale mafuta, timasunga minofu, kupereka zakudya ku ubongo, ndikuwonjezera moyo pamene chakudya chikusowa. M'malo mwake, ketosis imatha kuthandizira kuchepetsa kuchepa kwa thupi pakusala kudya ndi 5-fold.

Mwa kuyankhula kwina, kugwiritsa ntchito matupi a ketoni pamafuta kumachepetsa kufunikira kwathu kutentha minofu kuchokera ku 200 magalamu mpaka 40 magalamu patsiku chakudya chikusowa. Komabe, mukatsatira zakudya za ketogenic kuti muchepetse thupi, mudzataya magalamu ochepera a 40 a minofu patsiku chifukwa mudzakhala mukupatsa thupi lanu zakudya zopatsa minofu monga mapuloteni.

Kwa milungu ingapo mpaka miyezi ya ketosis yopatsa thanzi (pamene matupi anu a ketone ali pakati pa 0.5 ndi 3 mmol / L), matupi a ketone adzakwaniritsa 50% ya zosowa zanu za basal mphamvu ndi 70% ya ubongo wanu umasoweka. Izi zikutanthauza kuti mudzakhalabe ndi minofu yambiri mukamapeza zabwino zonse zoyaka ketone:

Kupititsa patsogolo kugwira ntchito kwachidziwitso ndi kumveka bwino m'maganizo

●Shuga wa m’magazi ndi wokhazikika

● Mphamvu zambiri

●Kutaya mafuta mosalekeza

● Kuchita bwino pamasewera

Chifukwa chiyani thupi lanu likufuna BHB? kuchokera kumakina owonera

Sikuti BHB imatithandiza kupewa atrophy ya minofu, komanso imapereka mafuta bwino kuposa shuga m'njira ziwiri:

●Amatulutsa ma free radicals ochepa.

● Zimatipatsa mphamvu zambiri pa molekyulu iliyonse.

Kupanga Mphamvu ndi Ma Radicals Aulere: Glucose (Shuga) vs. BHB

Tikapanga mphamvu, timapanga zinthu zovulaza zomwe zimatchedwa ma free radicals (kapena oxidants). Ngati zinthuzi zichulukana pakapita nthawi, zimatha kuwononga ma cell ndi DNA.

Panthawi yopanga ATP, mpweya ndi hydrogen peroxide zimatuluka. Awa ndi ma free radicals, omwe amatha kulimbana nawo mosavuta ndi ma antioxidants.

Komabe, alinso ndi kuthekera kochoka m'manja ndikusandulika kukhala ma free radicals owononga kwambiri (mwachitsanzo, mitundu ya nayitrogeni yokhazikika ndi ma hydroxyl radicals), omwe amachititsa kuwonongeka kwakukulu kwa okosijeni m'thupi.

Chifukwa chake, kuti mukhale ndi thanzi labwino, kudzikundikira kosalekeza kwa ma free radicals kuyenera kuchepetsedwa. Kuti tichite zimenezi, tiyenera kugwiritsa ntchito mphamvu zoyera ngati n’kotheka.

Glucose komanso kupanga ma free radicals

Glucose iyenera kudutsa njira yayitali pang'ono kuposa BHB isanalowe mu Krebs cycle kupanga ATP. Ntchitoyi ikamalizidwa, mamolekyu 4 a NADH adzapangidwa ndipo chiŵerengero cha NAD +/NADH chidzachepa.

NAD+ ndi NADH ndizodziwika bwino chifukwa zimayang'anira oxidant ndi antioxidant ntchito:

●NAD+ imateteza kupsinjika kwa okosijeni, makamaka vuto lililonse lomwe limayambitsidwa ndi chimodzi mwazinthu zomwe zatchulidwa kale: hydrogen peroxide. Imawonjezeranso autophagy (njira yoyeretsa ndi kukonzanso magawo a cell owonongeka). Pansi pa machitidwe osiyanasiyana a kagayidwe kachakudya, NAD + imakhala NADH, yomwe imakhala ngati ma electron shuttle yopanga mphamvu.

●NADH ndiyofunikanso chifukwa imapereka ma electron kuti apange ATP. Komabe, sizimateteza ku kuwonongeka kwa ma free radicals. Pakakhala NADH yochulukirapo kuposa NAD +, ma radicals ambiri aulere adzapangidwa ndipo ma enzyme oteteza adzaletsedwa.

Mwa kuyankhula kwina, nthawi zambiri, chiwerengero cha NAD +/NADH chimasungidwa bwino kwambiri. Miyezo yotsika ya NAD + imatha kuwononga kwambiri ma cell.

Popeza kagayidwe ka glucose kumadya mamolekyu 4 a NAD +, zomwe zili mu NADH zimakhala zapamwamba, ndipo NADH imayambitsa kuwonongeka kwa okosijeni. Mwachidule: Glucose samatenthedwa kwathunthu-makamaka poyerekeza ndi BHB.

BHB ndi kupanga kwaulere kwamphamvu

BHB sichidutsa glycolysis. Zimangosintha kubwerera ku acetyl-CoA musanalowe mumayendedwe a Krebs. Ponseponse, njirayi imangodya mamolekyu a 2 NAD +, ndikupangitsa kuti ikhale yogwira ntchito kuwirikiza kawiri kuposa shuga kuchokera pamawonekedwe opanga ma radical aulere.

Kafukufuku akuwonetsanso kuti BHB sichingangosunga chiŵerengero cha NAD +/NADH, komanso kukonza bwino. Izi zikutanthauza kuti BHB ikhoza:

● Pewani kupsinjika kwa okosijeni ndi okosijeni opangidwa panthawi ya kuwonongeka kwa ketone

● Imathandizira ntchito ya mitochondrial ndi kubereka

●Zimathandiza kupewa ukalamba komanso moyo wautali

BHB imagwiranso ntchito ngati antioxidant mwa kuyambitsa mapuloteni oteteza:

● UCP: Puloteniyi imatha kuchepetsa ma radicals aulere omwe amawukhira panthawi ya metabolism yamphamvu ndikuletsa kuwonongeka kwa okosijeni m'maselo.

●SIRT3: Thupi lanu likasintha kuchoka ku glucose kupita ku mafuta, puloteni yotchedwa Sirtuin 3 (SIRT3) imachuluka. Imayatsa ma antioxidants amphamvu omwe amasunga ma free radicals otsika panthawi yopanga mphamvu. Imakhazikitsanso jini ya FOXO ndikuletsa okosijeni.

●HCA2: BHB ikhoza kuyambitsanso puloteni yolandirira. Kafukufuku wambiri wasonyeza kuti izi zikhoza kufotokozera zotsatira za neuroprotective za BHB.

Ubwino 10 wa Beta-Hydroxybutyric Acid (BHB) Kuti Mulimbitse Thanzi Lanu

1. BHB imalimbikitsa kufotokoza kwa majini osiyanasiyana olimbikitsa thanzi.

BHB ndi "metabolite yowonetsera" yomwe imapangitsa kusintha kwa epigenetic m'thupi lonse. M'malo mwake, maubwino ambiri a BHB amachokera ku kuthekera kwake kokweza mafotokozedwe amtundu. Mwachitsanzo, BHB imalepheretsa mamolekyu omwe amaletsa mapuloteni amphamvu. Izi zimathandiza kufotokoza za majini opindulitsa monga FOXO ndi MTL1.

Kutsegula kwa FOXO kumatithandiza kuwongolera bwino kukana kupsinjika kwa okosijeni, kagayidwe kachakudya, kuzungulira kwa ma cell ndi apoptosis, zomwe zimakhudza kwambiri moyo wathu komanso nyonga zathu. Kuphatikiza apo, MLT1 imathandizira kuchepetsa kawopsedwe pambuyo pokondoweza mawu ake ndi BHB.

Izi ndi zitsanzo ziwiri zokha za zotsatira za majini a BHB pa maselo athu. Asayansi akufufuzabe ntchito zambiri za mamolekyu odabwitsawa.

2. BHB imachepetsa kutupa.

BHB imaletsa puloteni yotupa yotchedwa NLRP3 inflammasome. NLRP3 imatulutsa mamolekyu otupa omwe amapangidwa kuti athandize thupi kuchiritsa, koma akakwiya nthawi zonse amatha kuthandizira khansa, insulini kukana, matenda a mafupa, matenda a Alzheimer's, matenda a khungu, metabolic syndrome, mtundu wa 2 shuga ndi gout .

Kafukufuku wambiri wapeza kuti BHB ikhoza kuthandizira kupewa matenda omwe amayamba kapena kuwonjezereka chifukwa cha kutupa mwa kuchepetsa kutupa komwe kumayenderana ndi izi.

Mwachitsanzo, BHB (ndi zakudya za ketogenic) zingathandize kuchiza gout ndikupewa matenda a gout poletsa NLRP3.

3. BHB imateteza kupsinjika kwa okosijeni.

Kupsinjika kwa okosijeni kumalumikizidwa ndi kukalamba kofulumira komanso mavuto osiyanasiyana azaumoyo. Njira imodzi yochepetsera mavutowa ndikugwiritsa ntchito gwero lamafuta abwino kwambiri monga BHB.

Sikuti BHB ndi yothandiza kwambiri kuposa shuga, kafukufuku wapeza kuti ikhoza kuteteza ndi kubwezeretsa kuwonongeka kwa okosijeni mu ubongo ndi thupi lonse:

● BHB imateteza kukhulupirika kwa kugwirizana kwa neuronal mu hippocampus, gawo la ubongo lomwe limayang'anira maganizo, kukumbukira nthawi yaitali, ndi kuyenda kwa malo, kuchokera ku kuwonongeka kwa okosijeni.

● Mu cerebral cortex, dera la ubongo lomwe limayang'anira ntchito zapamwamba kwambiri monga kuzindikira, kulingalira kwa malo, chinenero, ndi malingaliro amalingaliro, BHB imateteza maselo a mitsempha ku ma radicals aulere ndi okosijeni.

● M'maselo a endothelial (maselo omwe ali m'mitsempha yamagazi), ma ketoni amatsegula machitidwe oteteza antioxidant omwe amateteza dongosolo la mtima.

● Kwa othamanga, matupi a ketone apezeka kuti amachepetsa kupsinjika kwa okosijeni komwe kumayambitsa masewera olimbitsa thupi.

4. BHB ikhoza kutalikitsa moyo.

Mwa kupeza zabwino ziwiri zomwe taphunzira kale (kuchepa kwa kutupa ndi ma jini), BHB ikhoza kukulitsa moyo wanu ndikupangitsa moyo wanu kukhala wolemera.

Umu ndi momwe BHB imalowera mu majini oletsa kukalamba:

● Tsekani jini yolandirira insulin ngati kukula kwake (IGF-1). Jini imeneyi imalimbikitsa kukula kwa maselo ndi kuchulukana, koma kuchulukitsitsa kumalumikizidwa ndi matenda, khansa, ndi kufa msanga. Ntchito yotsika ya IGF-1 imachedwetsa ukalamba ndikuwonjezera moyo.

● Yambitsani jini ya FOXO. Jini limodzi la FOXO, FOXO3a, lalumikizidwa ndi kuchuluka kwa moyo wa anthu chifukwa limalimbikitsa kupanga ma antioxidants.

 

5. BHB imawonjezera ntchito yachidziwitso.

Tidakambirana kale kuti BHB ndi gwero lofunikira lamafuta ku ubongo pomwe shuga ndi wotsika. Izi zili choncho chifukwa imatha kuwoloka chotchinga chamagazi-muubongo ndikupatsa mphamvu zoposa 70% za ubongo zomwe zimafunikira mphamvu.

Komabe, mapindu a ubongo wa BHB samatha pamenepo. BHB ikhozanso kupititsa patsogolo ntchito yachidziwitso mwa:

● Imagwira ntchito ngati mankhwala oteteza minyewa.

● Kupititsa patsogolo mphamvu ya mitochondrial ndi kubereka.

● Sinthani bwino pakati pa ma inhibitory and excitatory neurotransmitters.

● Limbikitsani kukula ndi kusiyanitsa kwa ma neuroni atsopano ndi kulumikizana kwa minyewa.

● Pewani kuwonongeka kwa ubongo ndi kuchuluka kwa zolembera.

Ngati mukufuna kuphunzira zambiri za momwe BHB imapindulira ubongo ndi kafukufuku kumbuyo kwake, onani nkhani yathu pa ketoni ndi ubongo.

6. BHB ingathandize kulimbana ndi khansa.

BHB imachepetsa kukula kwa zotupa zosiyanasiyana chifukwa maselo ambiri a khansa sangathe kugwiritsa ntchito matupi a ketone kuti akule ndi kufalikira. Izi nthawi zambiri zimachitika chifukwa cha kusokonezeka kwa metabolic kwa maselo a khansa, kuwapangitsa kudalira kwambiri shuga.

M'maphunziro angapo, asayansi agwiritsa ntchito kufooka uku pochotsa shuga, kukakamiza maselo a khansa kudalira matupi a ketone. Mwanjira imeneyi, iwo kwenikweni amachepetsa zotupa mu ziwalo zambiri, kuphatikizapo ubongo, kapamba ndi m'matumbo, chifukwa maselo sanathe kukula ndi kufalikira.

Komabe, ndikofunikanso kuzindikira kuti si makhansa onse omwe amachita mofanana, ndipo BHB singathandize kulimbana ndi kuteteza khansa zonse. Ngati mukufuna kudziwa zambiri za kafukufuku wa keto, zakudya za ketogenic, ndi khansa, onani nkhani yathu pamutuwu.

7. BHB imapangitsa chidwi cha insulin.

Matupi a Ketoni atha kuthandizira kusintha kukana kwa insulin chifukwa amatha kutsanzira zina mwazotsatira za insulin ndikuwongolera shuga wamagazi ndi insulin. Iyi ndi nkhani yabwino kwa aliyense amene ali ndi matenda a prediabetes kapena amtundu wa 2, kapena aliyense amene akufuna kukonza thanzi lawo lonse la metabolic.

8. BHB ndiye mafuta abwino kwambiri a mtima wanu.

Magwero amphamvu kwambiri a mtima ndi mafuta azidulo ataliitali. Ndiko kulondola, mtima umawotcha mafuta, osati ma ketoni, monga gwero lake lalikulu lamafuta.

Komabe, monga ubongo, mtima wanu ukhoza kusintha bwino ndi keto ngati pakufunika kutero.

Kafukufuku wapeza kuti mukawotcha BHB, thanzi la mtima wanu limakula m'njira zambiri 

● Kugwira ntchito bwino kwa mtima kumatha kuwonjezeka mpaka 30%

● Kutuluka kwa magazi kumatha kuonjezedwa mpaka 75%.

● Kupanikizika kwa okosijeni m'maselo a mtima kumachepa.

Kutengedwa pamodzi, izi zikutanthauza kuti BHB ikhoza kukhala mafuta abwino kwambiri a mtima wanu.

9. BHB imathandizira kutaya mafuta.

Kuwotcha ma ketoni pamafuta kumatha kulimbikitsa kutaya mafuta m'njira ziwiri:

● Powonjezera mphamvu zanu zowotcha mafuta ndi ketone.

●Pochepetsa chilakolako cha chakudya.

Pamene mukukhalabe ndi ketosis, mphamvu yanu yowotcha ma ketoni ndi mafuta ambiri idzawonjezeka kwambiri, ndikusandutsani makina oyaka mafuta. Kuphatikiza pa izi, mudzakhalanso ndi zotsatira zochepetsa chilakolako cha matupi a ketone.

Ngakhale kafukufuku sanafotokoze chifukwa chake kapena momwe ma ketoni amachepetsa chilakolako chathu, tikudziwa kuti kuwotcha kwa ketone kumawoneka kutsika kwa ghrelin, mahomoni anjala.

Tikaphatikiza zotsatira ziwiri izi za BHB pakuchepetsa thupi, timatha ndi mafuta omwe onse amalimbikitsa kuwotcha mafuta ndipo nthawi yomweyo amakulepheretsani kupeza mafuta (poletsa kugwiritsa ntchito kalori wowonjezera).

10. BHB imakulitsa luso lanu lolimbitsa thupi.

Pakhala pali kafukufuku wambiri wokhudza momwe BHB imakhudzira masewera olimbitsa thupi, koma zenizeni zikugwirabe ntchito (pun cholinga). Mwachidule, kafukufuku wapeza kuti ma ketones amatha:

●Kupititsa patsogolo kagwiridwe ka ntchito panthawi yochita masewera olimbitsa thupi motalika kwambiri (monga kukwera njinga, kukwera maulendo ataliatali, kuvina, kusambira, yoga yolimbitsa thupi, kuchita masewera olimbitsa thupi, kuyenda mtunda wautali).

● Wonjezerani kuwotcha mafuta ndikusunga masitolo a glycogen kuti muzichita masewera olimbitsa thupi kwambiri.

● Imathandiza kubweretsanso glycogen nkhokwe mutatha kuchita masewera olimbitsa thupi ndikufulumizitsa kuchira.

● Amachepetsa kutopa panthawi yochita zinthu komanso amapangitsa kuti ubongo uzigwira ntchito bwino.

Ponseponse, kafukufuku akuwonetsa kuti BHB ikhoza kuthandizira kuchepetsa kutopa, kuonjezera kupirira, komanso kupititsa patsogolo masewera olimbitsa thupi. Komabe, sizingawongolere magwiridwe antchito anu pamachitidwe apamwamba kwambiri monga kuthamanga ndi kukwera maweightlifting. (Kuti mudziwe chifukwa chake, omasuka onani kalozera wathu wa masewera a ketogenic .)

Pali njira ziwiri zowonjezerera ma BHB anu: mosalekeza komanso mopanda malire.

Endogenous BHB imapangidwa ndi thupi lanu palokha.

Ma ketoni akunja ndi mamolekyu akunja a BHB omwe amatha kutengedwa ngati chowonjezera kuti awonjezere kuchuluka kwa ketone. Izi nthawi zambiri zimatengedwa ngati mchere wa BHB kapena esters.

Njira yokhayo yokwaniritsira ndikusunga matupi a ketone ndi kupanga matupi a ketone. Exogenous ketone supplementation imatha kuthandizira, koma sikungalowe m'malo mwa ma ketosis opitilira muyeso.

Exogenous Ketosis: Zonse Zomwe Muyenera Kudziwa Zokhudza BHB Ketone Supplement

Pali njira ziwiri zodziwika zopezera ma ketoni akunja: mchere wa BHB ndi ma ketone esters.

Ketone esters ndi mawonekedwe oyambirira a BHB opanda zowonjezera zowonjezera. Ndi okwera mtengo, ovuta kuwapeza, amalawa kwambiri, ndipo amatha kukhala ndi zotsatira zoyipa pamatenda am'mimba.

Mchere wa BHB, kumbali ina, ndiwowonjezera wothandiza kwambiri womwe ndi wosavuta kugula, kudya, ndi kugaya. Ma ketones awa amapangidwa kuchokera ku kuphatikiza kwa BHB ndi mchere wamchere (ie potaziyamu, calcium, sodium, kapena magnesium).

Mchere wamchere umawonjezeredwa ku zowonjezera za BHB ku:

●Kulimba kwa matupi a ketone

● Sinthani kukoma

●Kuchepetsa matenda a m'mimba

●Pangani kuti azisakaniza ndi zakudya ndi zakumwa

Mukatenga mchere wa BHB, amathyoledwa ndikumasulidwa m'magazi anu. BHB ndiye imapita ku ziwalo zanu kumene ketosis imayamba, kukupatsani mphamvu.

Kutengera kuchuluka komwe mumatenga, mutha kulowa mu ketosis nthawi yomweyo. Komabe, mutha kukhalabe mu ketosis malinga ngati matupi a ketone akupitilira (pokhapokha mutakhala pazakudya za ketogenic ndipo mukupanga kale matupi a ketone).

Ketone Ester (R-BHB) & Beta-Hydroxybutyrate (BHB)

Beta-hydroxybutyrate (BHB) ndi imodzi mwamatupi atatu akuluakulu a ketone omwe amapangidwa ndi chiwindi panthawi ya zakudya zochepa zama carbohydrate, kusala kudya, kapena kuchita masewera olimbitsa thupi kwa nthawi yayitali. Miyezo ya glucose ikatsika, BHB imakhala ngati gwero lamphamvu lopangira ubongo, minofu, ndi minyewa ina. Ndi molekyulu yochitika mwachilengedwe yomwe imagwira ntchito yofunika kwambiri mu metabolic state of ketosis.

Ketone ester (R-BHB), kumbali ina, ndi mawonekedwe opangidwa a BHB omangidwa ku molekyulu ya mowa. Mawonekedwe a esterified ndi bioavailable kwambiri komanso othandiza pakuwonjezeka kwa matupi a ketone m'magazi kuposa mchere wamba wa BHB. R-BHB imagwiritsidwa ntchito mowirikiza muzowonjezera kuti ziwongolere masewera olimbitsa thupi, chidziwitso, komanso mphamvu zonse.

Thupi likalowa mu ketosis, limayamba kuphwanya mafuta acids kukhala ma ketoni, kuphatikizapo BHB. Izi ndizochitika mwachilengedwe kutengera nthawi ya kuchepa kwa ma carbohydrate, zomwe zimapangitsa kuti thupi likhalebe ndi mphamvu. BHB ndiye imatengedwa kudzera m'magazi kupita kumagulu osiyanasiyana, komwe imasandulika kukhala mphamvu.

R-BHB ndi mawonekedwe owonjezereka, amphamvu kwambiri a BHB omwe amatha kuonjezera msanga ma ketones a magazi. Izi zimapangitsa kukhala njira yosangalatsa kwa iwo omwe akufuna mapindu a ketosis popanda zoletsa zoletsa zakudya. Kafukufuku akuwonetsa kuti R-BHB imatha kupititsa patsogolo magwiridwe antchito amthupi, kupititsa patsogolo chidziwitso, komanso kuthandizira kuonda.

Momwe mungasankhire mchere wabwino wa BHB kwa inu

Mukafuna mchere wabwino kwambiri wa BHB, onetsetsani kuti mukuchita zinthu zitatu izi:

1. Yang'anani BHB yambiri komanso mchere wochepa

Zowonjezera zapamwamba zimakulitsa BHB yachilendo ndikuwonjezera mchere wofunikira wa mchere.

Mchere wamchere womwe umagwiritsidwa ntchito kwambiri pamsika ndi sodium, potaziyamu, magnesium, ndi calcium, ndipo zambiri zowonjezera zimagwiritsa ntchito atatu mwa iwo, ngakhale ena amagwiritsa ntchito imodzi kapena ziwiri zokha.

Yang'anani chizindikirocho kuti muwonetsetse kuti pali mchere wosakwana 1 gramu ya mchere uliwonse. Kuphatikizika kwa mchere wa BHB sikumafuna zambiri kuposa 1 gramu ya mchere uliwonse kuti ukhale wogwira mtima

2. Onetsetsani kuti mukupeza mchere womwe mukufuna.

Osapeza potaziyamu, sodium, calcium kapena magnesium mokwanira? Sankhani zinthu za BHB kuti zikupatseni mchere womwe mukufuna.

3. Khalani kutali ndi zodzaza ndi ma carbs owonjezera.

Zodzaza ndi zowonjezera monga guar chingamu, xanthan chingamu, ndi silica ndizofala mumchere wa ketone wakunja ndipo ndizosafunikira kwenikweni. Nthawi zambiri sakhala ndi zotsatira zoyipa zaumoyo, koma amatha kukuberani mchere wamtengo wapatali wa BHB.

Kuti mupeze mchere wa keto wabwino kwambiri, ingoyang'anani gawo lazakudya zomwe zimati "Zosakaniza Zina" ndikugula mankhwalawo ndi mndandanda waufupi kwambiri wa zosakaniza zenizeni.

Ngati mumagula mchere wa BHB keto wokoma, onetsetsani kuti ali ndi zosakaniza zenizeni komanso zotsekemera za carb zochepa. Pewani zowonjezera zomwe zili ndi ma carbohydrate monga maltodextrin ndi dextrose.

Suzhou Myland Pharm & Nutrition Inc. ndi wopanga olembetsedwa ndi FDA yemwe amapereka Ketone Ester (R-BHB) yapamwamba komanso yoyera kwambiri.

Ku Suzhou Myland Pharm tadzipereka kupereka zinthu zapamwamba kwambiri pamitengo yabwino kwambiri. Ketone Ester (R-BHB) yathu ya ufa imayesedwa mwamphamvu kuti ikhale yoyera ndi potency, kuonetsetsa kuti mumapeza chithandizo chapamwamba chomwe mungakhulupirire. Kaya mukufuna kuthandizira thanzi la ma cell, kulimbikitsa chitetezo chamthupi kapena kukulitsa thanzi labwino, Ketone Ester (R-BHB) yathu ndiye chisankho chabwino kwambiri.

Ndi zaka 30 zachidziwitso komanso motsogozedwa ndiukadaulo wapamwamba komanso njira zokongoletsedwa bwino za R&D, Suzhou Myland Pharm yapanga zinthu zambiri zampikisano ndikukhala kampani yotsogola ya sayansi ya moyo, kaphatikizidwe kazinthu ndi ntchito zopanga.

Kuphatikiza apo, Suzhou Myland Pharm ndiwopanganso zolembedwa ndi FDA. Zothandizira zamakampani za R&D, malo opangira, ndi zida zowunikira ndi zamakono komanso zimagwira ntchito zambiri, ndipo zimatha kupanga mankhwala kuchokera ku ma milligrams mpaka matani mu sikelo, ndikutsatira miyezo ya ISO 9001 ndi mafotokozedwe a GMP.