M'zaka zaposachedwa, anthu akhala ndi moyo wosamala kwambiri za thanzi, ndipo pofuna kukhala ndi thanzi labwino komanso thanzi labwino, nthawi zambiri timayang'ana njira zothetsera matenda osiyanasiyana.Chowonjezera chimodzi chodalirika chomwe chadziwika kwambiri m'zaka zaposachedwa ndi palmitoylethanolamide (PEA).Podziwika chifukwa cha machiritso ake, PEA yakhala ikuphunziridwa mozama chifukwa cha mphamvu yake yochepetsera ululu, kutupa, ndi kupititsa patsogolo thanzi labwino.
Palmitoylethanolamide (PEA) ndi mafuta acid omwe amapezeka mwachilengedwe opangidwa ndi matupi athu poyankha kutupa ndi kupweteka.Ndi m'gulu la mankhwala omwe amadziwika kuti N-acylethanolamines (NAE), omwe amakhala ngati amkati amafuta acid amides, mamolekyu a lipid omwe amakhudzidwa pakuwongolera njira zosiyanasiyana zathupi.Anapezeka koyamba m'ma 1950, koma machiritso ake sanapezeke mpaka patapita nthawi.
PEA imapezeka m'matenda osiyanasiyana aumunthu ndipo yapezeka kuti ili ndi gawo lofunikira pakuwongolera ndikusintha momwe chitetezo cha mthupi chimayankhira komanso kutupa.
Amadziwika kuti amalumikizana ndi zolandilira zina m'thupi, kuphatikiza peroxisome proliferator-activated receptor-alpha (PPAR-α), yomwe imakhudzidwa ndi kuwongolera kutupa.Poyambitsa PPAR-α, PEA imathandizira kuletsa kupanga mamolekyu oletsa kutupa, kupititsa patsogolo njira zachilengedwe zolimbana ndi kutupa m'thupi.
PEA imagwira ntchito poletsa kuyambitsa kwa maselo apadera otchedwa mast cell, omwe amamasula oyimira pakati otupa ndikupangitsa kuwawa ndi kusagwirizana.Pochepetsa mast cell activation, PEA imathandizira kuchepetsa ululu ndikuwongolera moyo wonse.
Kafukufuku wasonyeza kuti PEA imatha kuteteza matenda osiyanasiyana amitsempha mwa kupewa kuwonongeka kwa neuronal komanso kulimbikitsa kukula ndi kupulumuka kwa maselo amitsempha.
PEA imagwira ntchito poyang'ana ndikumangiriza ku cholandirira china chotchedwa peroxisome proliferator-activated receptor-alpha (PPAR-α).Receptor iyi imagwira ntchito yofunika kwambiri pakuwongolera kutupa ndi kuzindikira kowawa.Poyambitsa PPAR-alpha receptors, PEA imathandizira kuchepetsa kutupa ndikuchepetsa ululu.
Palmitoylethanolamide (PEA) Ubwino ndi Ntchito:
●Kusamalira ululu: PEA yasonyeza zotsatira zodalirika pochiza mitundu yosiyanasiyana ya ululu, kuphatikizapo ululu wosatha, ululu wa neuropathic, ndi ululu wopweteka.Zimagwira ntchito pochepetsa kutupa ndikusintha zizindikiro zowawa, kupereka mpumulo kwa anthu omwe ali ndi ululu wosalekeza.
●Neuroprotective: PEA yapezeka kuti ili ndi neuroprotective katundu, kutanthauza kuti imathandiza kuteteza ndi kuthandizira thanzi la mitsempha ya mitsempha.Izi zimapangitsa kuti zikhale zopindulitsa pa matenda monga multiple sclerosis, matenda a Alzheimer's ndi Parkinson's disease, momwe kuwonongeka kwa mitsempha ya mitsempha ndi kutupa zimagwira ntchito yofunika kwambiri.
●Anti-inflammatory effect: PEA ili ndi mphamvu yotsutsa-kutupa ndipo imapindulitsa ku matenda osiyanasiyana otupa, monga nyamakazi, matenda opweteka a m'mimba (IBS) ndi mphumu.Zimathandizira kuchepetsa kupanga mamolekyu oletsa kutupa, potero kuchepetsa kutupa ndi zizindikiro zake.
●Thandizo la chitetezo chamthupi: PEA yawonetsedwa kuti ndi immunomodulatory, zomwe zikutanthauza kuti zimathandiza kuwongolera ndikusintha momwe chitetezo cha mthupi chimayankhira.Izi zitha kukhala zopindulitsa pamatenda a autoimmune, monga nyamakazi ya nyamakazi ndi lupus, momwe chitetezo chamthupi chimaukira molakwika minofu yake.
●Antidepressant ndi anxiolytic zotsatira: PEA yapezeka kuti ili ndi mphamvu zochepetsera nkhawa komanso nkhawa.Zimathandizira kuwongolera malingaliro ndikuchepetsa zizindikiro za kupsinjika ndi nkhawa powongolera ma neurotransmitters osiyanasiyana omwe amakhudzidwa ndi kuwongolera malingaliro, monga serotonin ndi dopamine.
●Thanzi Lapakhungu: PEA yapezeka kuti ili ndi zinthu zotsitsimula komanso zoletsa kuyabwa, zomwe zimapangitsa kuti ikhale yothandiza pochiza matenda osiyanasiyana akhungu, monga eczema, psoriasis, ndi dermatitis.Imathandiza kuchepetsa kutupa ndi kuyabwa, kulimbikitsa thanzi, bwino khungu.
CBD, yotengedwa ku chomera cha hemp, ndiyotchuka chifukwa cha kuthekera kwake kupereka zopindulitsa monga kuchepetsa ululu, kuchepetsa nkhawa komanso kugona bwino.Kumbali ina, PEA, mwachilengedwe mafuta asidi amide, yaphunziridwa mozama chifukwa cha mankhwala ake odana ndi kutupa ndi analgesic.Mitundu iwiriyi imapangidwa mwachilengedwe m'matupi athu ndipo imapezekanso muzakudya zina.
Kusiyanitsa kwakukulu pakati pa PEA ndi CBD ndi momwe aliyense amagwirira ntchito mthupi lathu.CBD imagwirizana kwambiri ndi dongosolo lathu la endocannabinoid (ECS), gulu la zolandilira zomwe zimayang'anira machitidwe osiyanasiyana amthupi, kuphatikiza kumva kupweteka, kukhumudwa, ndi kutupa.CBD imakhudza mwachindunji ECS powonjezera kupanga endocannabinoid kapena kuletsa kuwonongeka kwawo.
Komabe, PEA imagwira ntchito m'njira zosiyanasiyana.Imalunjika ndikuwongolera ntchito za machitidwe ena ambiri m'thupi lathu, makamaka omwe amakhudzidwa ndi kuwongolera ululu ndi kutupa.PEA imagwirizana ndi zolandilira zingapo, monga peroxisome proliferator-activated receptor-α (PPAR-α), yomwe imakhala ndi gawo lofunikira pakuwongolera ululu.
Ngakhale kuti PEA ndi CBD zili ndi zotsutsana ndi zotupa, zochita za PEA zikuwoneka kuti ndizokhazikika, zomwe zimayang'ana mamolekyu opweteka, pamene CBD imakhala ndi zotsatira zambiri pazochitika zotupa.Kusiyana kwamakina kumeneku kumatha kufotokoza chifukwa chake PEA imagwiritsidwa ntchito nthawi zambiri kuthana ndi zowawa za komweko, pomwe CBD nthawi zambiri imagwiritsidwa ntchito kwambiri pochiza kutupa kwadongosolo.
Chinthu chinanso chosiyana ndi chikhalidwe chalamulo cha magulu awiriwa m'mayiko ena.CBD, yochokera ku hemp, imakhala ndi zoletsa ndi malamulo osiyanasiyana, makamaka chifukwa cholumikizana ndi hemp.Mosiyana ndi izi, PEA imayikidwa ngati chowonjezera chazakudya ndipo nthawi zambiri chimawonedwa ngati chotetezeka komanso chovomerezeka kugwiritsa ntchito.
Ngakhale kuti mankhwala onsewa ali ndi mphamvu zochizira, mbiri yawo yachitetezo imasiyana.CBD yaphunziridwa mozama ndipo nthawi zambiri imawonedwa ngati yotetezeka, ndi zotsatira zochepa zomwe zimanenedwa.Komabe, zimatha kuyanjana ndi mankhwala ena ndipo sizingakhale zoyenera kwa aliyense, makamaka omwe ali ndi matenda a chiwindi.PEA, kumbali ina, ndi chinthu chomwe chimapezeka mwachibadwa m'matupi athu ndipo chakhala chikugwiritsidwa ntchito motetezeka ngati chakudya chowonjezera kwa zaka zambiri.
Ndikoyenera kutchula kuti PEA ndi CBD sizosiyana.Ndipotu, anthu ena amasankha kugwiritsa ntchito mankhwala onse pamodzi chifukwa amatha kukhala ndi zotsatira zowonjezera.Mwachitsanzo, zochulukirapo zotsutsana ndi zotupa za CBD zitha kuphatikizidwa ndi ma analgesic amtundu wa PEA kuti athetseretu ululu.
Malangizo a Mlingo:
Poganizira za mlingo woyenera wa palmitoylethanolamide, ndikofunika kukumbukira kuti zosowa za munthu aliyense zimasiyana.Nthawi zonse tikulimbikitsidwa kukaonana ndi dokotala wodziwa bwino zachipatala musanayambe mankhwala atsopano.Komabe, nayi malangizo amomwe mungayambitsire:
1.Yambani ndi mlingo wochepa: Kuyambira ndi mlingo wochepa umalepheretsa kuti thupi likhale lolemera ndipo limalola kusintha.
2.Onjezani pang'onopang'ono: patatha masiku angapo, ngati palibe zovuta zomwe zimachitika, ndikofunikira kudziwa kuti kuleza mtima ndi kusasinthasintha ndizofunikira pakuphatikiza PEA m'zochita zanu zatsiku ndi tsiku.
3.Yang'anani momwe munthu angayankhire: Thupi la aliyense ndi losiyana, kotero zingatenge nthawi kuti mudziwe mlingo wabwino kwambiri wa zosowa zanu.Samalani kwambiri momwe thupi lanu limayankhira, ndipo funsani akatswiri azachipatala kuti akuthandizeni panjira.
malangizo ogwiritsa ntchito:
Kuphatikiza pa mlingo, ndikofunikiranso kudziwa njira zabwino zogwiritsira ntchito palmitoylethanolamide.Ganizirani malangizo otsatirawa kuti muwonjezere phindu la PEA:
1.Kusasinthasintha ndikofunikira: Kuti mukhale ndi chithandizo chokwanira cha PEA, kugwiritsa ntchito mosasinthasintha ndikofunikira.Kutenga mlingo wovomerezeka pafupipafupi kwa nthawi yayitali kumathandiza thupi kusintha ndikukwaniritsa zabwino za PEA.
2.Awiriawiri okhala ndi zakudya zopatsa thanzi: PEA imagwira ntchito mogwirizana ndi zakudya zathanzi.Kuphatikizika ndi zakudya zopatsa thanzi zomwe zili ndi michere yofunika kwambiri kungapangitse mapindu ake ndikulimbikitsa thanzi labwino.
3.Phatikizanipo kusintha kwa moyo: Kukhala ndi moyo wathanzi, kuphatikiza masewera olimbitsa thupi, kuwongolera kupsinjika, komanso kugona kwabwino, kumatha kupititsa patsogolo zotsatira za PEA.Kusintha kwa moyo kumayendera limodzi ndi PEA supplementation kuti mukhale ndi thanzi labwino.
Q: Kodi palmitoylethanolamide ingapezeke bwanji?
A: Palmitoylethanolamide imapezeka ngati chowonjezera cha zakudya mu mawonekedwe a makapisozi kapena ufa.Itha kugulidwa m'masitolo ogulitsa zakudya, ma pharmacies, kapena ogulitsa pa intaneti.Komabe, ndi bwino kukaonana ndi dokotala musanayambe kugwiritsa ntchito, makamaka ngati muli ndi vuto linalake kapena mukumwa mankhwala.
Q: Kodi palmitoylethanolamide ingagwiritsidwe ntchito ngati chithandizo chodziyimira pawokha kapena kuphatikiza ndi mankhwala ena?
A: Palmitoylethanolamide ingagwiritsidwe ntchito ngati chithandizo chodziyimira pazochitika zina, makamaka kupweteka kosalekeza.Komabe, nthawi zina, imatha kukhala yothandiza kwambiri ikagwiritsidwa ntchito ngati chithandizo chothandizira limodzi ndi mankhwala ochiritsira.Kugwiritsiridwa ntchito kwa palmitoylethanolamide kuyenera kukambidwa ndi katswiri wa zachipatala kuti adziwe njira yoyenera yothandizira pa zosowa za munthu aliyense.
Chodzikanira: Nkhaniyi ndi yongofuna kudziwa zambiri ndipo siyenera kutengedwa ngati upangiri wachipatala.Nthawi zonse funsani akatswiri azachipatala musanagwiritse ntchito zowonjezera kapena kusintha dongosolo lanu lazaumoyo.
Nthawi yotumiza: Aug-21-2023
