Wopanga ufa wa Galantamine Hydrobromide Nambala ya CAS: 1953-04-4 98% kuyera kwa mphindi zochepa kwa zosakaniza zowonjezera
Magawo a Zamalonda
| Dzina la chinthu | Galantamine Hydrobromide |
| Dzina lina | Galanthamine hydrobromide; Galantamine HBr; Galanthamine HBr;(4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, Hydrobromide |
| Nambala ya CAS | 1953-04-4 |
| Fomula ya maselo | C17H21NO3.HBr |
| Kulemera kwa maselo | 368.27 |
| Chiyero | 98.0% |
| Maonekedwe | ufa woyera mpaka woyera pang'ono |
| Kulongedza | 1kg/thumba 10kgs, 25kgs/ng'oma |
| Kugwiritsa ntchito | mankhwala a nootropic |
Chiyambi cha malonda
Galantamine hydrobromide ndi benzazepine yochokera ku mababu ndi maluwa a narcissus, osmanthus, kapena canna. Ndi choletsanso cholinesterase pakamwa. Monga ligand ya nicotinic acetylcholine receptors, yakhala ikugwiritsidwa ntchito kwambiri kupititsa patsogolo ntchito ya ubongo. Ntchito yake ndikuletsa acetylcholinesterase mopikisana komanso mosinthika, motero kumawonjezera kuchuluka kwa acetylcholine. Galantamine hydrobromide ikalowetsedwa m'magazi, imalowetsedwa mosavuta m'magawo osiyanasiyana a thupi, kuphatikiza ubongo. Imamatira ku nicotinic acetylcholine receptors, zomwe zimapangitsa kusintha kwa mawonekedwe ndikuwonjezera kutulutsidwa kwa acetylcholine. Imagwiranso ntchito popikisana ndi ndikubweza zotsatira za cholinesterase inhibitors. Mwa kuletsa cholinesterase, imaletsa kuwonongeka kwa acetylcholine, motero imawonjezera milingo ndi nthawi ya neurotransmitter yamphamvu iyi. Galantamine ingathandizenso kuphunzira ndi kukumbukira, kupewa kutupa kwa ubongo, ndikusunga milingo yayikulu ya neurotransmitters posunga umphumphu wa ma neuron ndi ma synapses.
Mbali
(1) Kuyera Kwambiri: Galantamine hydrobromide ikhoza kukhala chinthu choyera kwambiri kudzera mu njira zopangira zinthu zoyengedwa bwino. Kuyera Kwambiri kumatanthauza kupezeka bwino kwa bioavailability komanso kuchepetsa zotsatirapo zoyipa.
(2) Chitetezo: Galantamine hydrobromide yatsimikiziridwa kuti ndi yotetezeka ku thupi la munthu.
(3) Kukhazikika: Galantamine hydrobromide ili ndi kukhazikika kwabwino ndipo imatha kusunga ntchito yake ndi mphamvu zake pansi pa malo osiyanasiyana komanso malo osungiramo zinthu zosiyanasiyana.
Mapulogalamu
Monga chowonjezera pazakudya, galantamine hydrobromide imatha kukonza kukumbukira, kuzindikira, komanso kugwira ntchito za tsiku ndi tsiku. Imagwira ntchito pobwezeretsa bwino zinthu zina zachilengedwe (ma neurotransmitters) muubongo, zomwe zimawonjezera liwiro la kukumbukira ndikusunga tsatanetsatane ndi mfundo. Kuphatikiza apo, galantamine hydrobromide imakhudza mwachindunji kapena mwanjira ina neuroplasticity. Imalimbikitsa synaptic plasticity mwa kuyambitsa microglia ndi astrocytes. Galantamine imapereka chitetezo cha antioxidant ku oxidative stress yomwe imachitika chifukwa cha ma free radicals.
